Results 131 to 140 of about 68,755 (290)

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source

Long‐Term Effects of Xenotransplantation of Human Enteric Glia in an Immunocompetent Rat Model of Acute Brain Injury

Advanced Science, EarlyView.
Acute brain injuries are characterized by extensive tissue damage, resulting in debilitating deficits in patients. Despite considerable progress, cell‐based approaches have yet to identify an ideal candidate. This long‐term study explores the use of an untested cell source – human enteric glia – and a non‐invasive administration route – intranasal ...
Nina Colitti, Edwige Rice, Franck Desmoulin, Maylis Combeau, Mélissa Parny, Lorenne Robert, Etienne Buscail, Barbara Bournet, Nathalie Vergnolle, Isabelle Raymond‐Letron, Isabelle Loubinoux, Carla Cirillo   +11 more
wiley   +1 more source

Gene targeting of GAN in mouse causes a toxic accumulation of microtubule-associated protein 8 and impaired retrograde axonal transport [PDF]

, 2006
Jianqing Ding, K. Elizabeth Allen, Wei Wang, Angela Valle, Chengbiao Wu, Timothy Nardine, Bianxiao Cui, Jing Yi, Anne Marion Taylor, Noo Li Jeon, Steven Chu, Yuen T. So, Hannes Vogel, Ravi Tolwani, William C. Mobley, Yanmin Yang   +15 more
openalex   +1 more source

Delta Opioid Receptors within the Cortico‐Thalamic Circuitry Underlie Hyperactivity Induced by High‐Dose Morphine

Advanced Science, EarlyView.
Morphine activates the excitatory cingulate cortex–intermediate rostrocaudal division of zona incerta (Cg‐ZIm) pathway to drive hyperlocomotion in mice. Inhibiting the Cg‐ZIm pathway attenuates both acute and chronic morphine‐induced hyperlocomotion, while its activation mimics morphine's motor effects.
Chun‐Yue Li, Huiqian Huang, Xiao‐Fan Shen, Ke‐Lei Cao, Di Zheng, Yi Zhu, Shi‐Ze Xie, Xiao‐Dan Yu, Hao Wang, Jia‐Dong Chen, Jie Shi, Yue Li, Min Yan, Xiao‐Ming Li   +13 more
wiley   +1 more source

Subcellular localization and axonal transport of the survival motor neuron (SMN) protein in the developing rat spinal cord [PDF]

, 2000
Silvia Pagliardini
openalex   +1 more source

Cryopreserved Human Otic Neuronal Spheroids Self‐assemble for Functional Connectivity Analysis and Long‐term Ototoxicity Evaluation

Advanced Science, EarlyView.
This study establishes a robust and reproducible protocol for generating human otic neuronal spheroids (hONS) from cryopreserved hPSC‐derived pre‐placodal ectoderm cells. These hONS further differentiate into functional SGN‐like neurons, which extend neurite projections toward both murine hair cells and human cortical organoids, thereby forming ...
Gaoying Sun, Yukai Wang, Man Wang, Xinyue Wang, Mingming Tang, Da Li, Jianhuan Qi, Xue Wang, Shujuan Sun, Lei Chen, Weibin An, Ligang Kong, Anqi Suo, Haibo Wang, Wenwen Liu, Lei Xu   +15 more
wiley   +1 more source

Tau, microtubule dynamics, and axonal transport: New paradigms for neurodegenerative disease. [PDF]

Bioessays, 2023
Cario A, Berger CL.
europepmc   +1 more source

Inhibition of kinesin synthesis and rapid anterograde axonal transport in vivo by an antisense oligonucleotide

, 1993
Anil Amaratunga, Peter J. Morin, K S Kosik, Richard E. Fine   +3 more
openalex   +1 more source

Comment on ‘A method to quantify regional axonal transport blockade at the optic nerve head after short term intraocular pressure elevation in mice by A. Korneva et al. ’(Exp. Eye Res. doi: https://doi.org/10.1016/j.exer.2020.108035)

, 2020
Robert J. Casson, Glyn Chidlow, John P. M. Wood   +2 more
openalex   +2 more sources

Enhanced  -secretase processing alters APP axonal transport and leads to axonal defects [PDF]

, 2012
Elisandra Márcia Rodrigues, April M. Weissmiller, Lawrence S.B. Goldstein   +2 more
openalex   +1 more source