Characterization of the binding properties and retrograde axonal transport of a monoclonal antibody directed against the rat nerve growth factor receptor. [PDF]
, 1985 Megumi Taniuchi, E. Marshall Johnson
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Rational Design of Inner Ear Drug Delivery Systems
Advanced Science, EarlyView.Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu +5 more
wiley +1 more source
Localization of axonally transported 125I-wheat germ agglutinin beneath the plasma membrane of chick retinal ganglion cells. [PDF]
, 1983 The distribution of 125I-wheat germ agglutinin (WGA) transported by axons of chick retinal ganglion cells to layer d of the optic tectum was studied by electron microscopic autoradiography.
LaVail, JH, McDonald, DM, Sugino, IK
core
Fast axonal transport of foreign synaptic vesicles in squid axoplasm. [PDF]
, 1985 Trina A. Schroer +2 more
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Axonal transport and the eye. [PDF]
British Journal of Ophthalmology, 1976 Tavistock Square, Wc H, London
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Cryptic Splicing of GAP43 mRNA is a Novel Hallmark of TDP‐43‐Associated ALS and AD
Advanced Science, EarlyView.TDP‐43 dysfunction disrupts RNA processing, inducing cryptic exon 4a1 inclusion in GAP43 and reducing its protein levels. This aberrant splicing impairs axonal regeneration and contributes to neurodegeneration in ALS and AD. RNA‐seq of patient brains reveals GAP43 downregulation and 4a1 upregulation, identifying cryptic exon 4a1 as a potential ...
Mingming Yang +9 more
wiley +1 more source
Advanced Science, EarlyView.Nonsyndromic orofacial clefts (NSOFCs) are the most common craniofacial defects. Exome sequencing of 214 sporadic cases sheds new light on its genetic architecture and identifies many candidate pathogenic variants. Furthermore, functional studies establish BOC as a novel causal gene and reveal an unusual two‐locus model of inheritance via the epistatic
Qing He +16 more
wiley +1 more source
Older but not slower: aging does not alter axonal transport dynamics of signalling endosomes in vivo [PDF]
, 2016 Efficient bi-directional axonal transport is critical for the function and survival of neurons. Defects in this process have been identified in early stages of several late-onset neurological disease models.
Schiavo, G, Sleigh, J
core
Slow axonal transport in acrylamide neuropathy: different abnormalities produced by single-dose and continuous administration [PDF]
, 1985 BG Gold, JW Griffin, DL Price
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Blockage of axonal transport induced by acute, graded compression of the rabbit vagus nerve. [PDF]
, 1980 Björn Rydevik +3 more
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