Results 131 to 140 of about 436,100 (389)
Neural Regeneration Research, 2015 OBJECTIVE: To assess the efficacy and safety of cilostazol on the progression and regression of symptomatic intracranial artery stenosis. DATA RETRIVAL: We searched the main databases for eligible trials including Medline (from 1966 to June 2014), Embase
Wenhui Zhang, Fangfang Cai, Zhongmin Wen
doaj +1 more source
In vivo measurement of afferent activity with axon-specific calcium imaging. [PDF]
, 2018 In vivo calcium imaging from axons provides direct interrogation of afferent neural activity, informing the neural representations that a local circuit receives.
Broussard, Gerard Joey +8 more
core
Localization of α-synuclein in teleost central nervous system: immunohistochemical and Western blot evidence by 3D5 monoclonal antibody in the common carp, Cyprinus carpio [PDF]
, 2015 Alpha synuclein (α-syn) is a 140 amino acid vertebrate-specific protein, highly expressed in the human nervous system and abnormally accumulated in Parkinson's disease and other neurodegenerative disorders, known as synucleinopathies.
CASINI, Arianna +6 more
core +1 more source
Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury
Advanced Functional Materials, EarlyView.After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen +9 more
wiley +1 more source
Robust Regeneration of Adult Sensory Axons in Degenerating White Matter of the Adult Rat Spinal Cord
Journal of Neuroscience, 1999 We have recently reported that minimally disturbed adult CNS white matter can support regeneration of adult axons by using a novel microtransplantation technique to inject minute volumes of dissociated adult rat dorsal root ganglion neurons directly into
S. Davies +3 more
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu +7 more
wiley +1 more source
Tetrodotoxin Blockage of Sodium Conductance Increase in Lobster Giant Axons
The Journal of General Physiology, 1964 Previous studies suggested that tetrodotoxin, a poison from the puffer fish, blocks conduction of nerve and muscle through its rather selective inhibition of the sodium-carrying mechanism.
T. Narahashi, JOHN W. Moore, W. R. Scott
semanticscholar +1 more source
Proceedings of the National Academy of SciencesAlready in the late 19th / early 20th century, neuroscientists such as Wilhelm His, Ross Granville Harrison, and Paul Weiss, discussed the role of mechanical signals in neuronal development (1-4). A few decades later, in two seminal papers, Dennis Bray showed that extending neuronal processes (‘neurites’) are under tension, and that the external ...
openaire +3 more sources
3D‐Printed Scaffolds Promote Enhanced Spinal Organoid Formation for Use in Spinal Cord Injury
Advanced Healthcare Materials, EarlyView.3D‐printed organoid scaffolds with microscale channels are developed to enhance spinal cord injury recovery by guiding region‐specific spinal neural progenitor cells. These scaffolds promote axonal growth, cell maturation, and neuronal network formation.
Guebum Han +8 more
wiley +1 more source
Frontiers in Cellular Neuroscience, 2018 Recent advances in fast volumetric imaging have enabled rapid generation of large amounts of multi-dimensional functional data. While many computer frameworks exist for data storage and analysis of the multi-gigabyte Ca2+ imaging experiments in neurons ...
Iaroslav Savtchouk +2 more
doaj +1 more source