Results 141 to 150 of about 228,091 (312)
F O, SCHMITT, N, GESCHWIND
openaire +2 more sources
Title on signature sheet: Axonopathy in peripheral myelin protein22 (pmp22) insufficiency
The role that various myelin membrane proteins play during development and disease processes is not well understood. To better understand their role in vivo we have crossed transgenic mice possessing a single truncated pmp22 gene with mice expressing ...
Zamani, Atiq
core
Representative TEM images of neurofilaments in axons.
6nm Au-nanoparticles, outlined in yellow, were used to measure areal density and spacing between neurofilaments for each image. (A-C) In Control axons, Au-nanoparticles are regularly spaced along the length of the axon and across the axon diameter. (D-F)
Arun Venkatesan (626378) +5 more
core +1 more source
Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes +14 more
wiley +1 more source
Neurofilament quantification in axons.
Each circle represents a single measure for the Control (blue) or Crushed (red) groups. Linear fits (solid lines) are shown to estimate the relationship between axon diameter and neurofilament metrics with 95% confidence intervals (dashed lines). (A-C) A
Arun Venkatesan (626378) +5 more
core +1 more source
A Critical Time Window of Neocortex Modulation for Remote Fear Memory in Rats and Humans
This study identifies a delayed consolidation window around 18 h after fear learning in the mPFC essential for remote fear memory. VTA dopaminergic input during this window sustains remote memory in rats, while non‐invasive stimulation of homologous human mPFC at the corresponding time selectively weakens remote but not recent fear memory, revealing a ...
Lu Cao +19 more
wiley +1 more source
This music score was submitted for the Kaleidoscope 2020 Call for Scores, an open access collaboration with the UCLA Music Library.
openaire +3 more sources
The structural and functional integrity of peripheral nerves depends on the glial-derived signal desert hedgehog [PDF]
We show that desert hedgehog ( dhh), a signaling molecule expressed by Schwann cells, is essential for the structural and functional integrity of the peripheral nerve.
Umehara, F +6 more
core
Activity-Dependent Development of Calcium Regulation in Growing Motor Axons
In cultured nerve cord explants from the crayfish (Procambarus clarkii), the normal impulse activity levels of growing motor axons determine their response to Ca2+influx.
Gregory A. Lnenicka +2 more
core +1 more source
Charting Endocrine Progenitors Across Species and Organs
Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing +21 more
wiley +1 more source

