Results 221 to 230 of about 448,604 (375)

Femtosecond‐Laser‐Fabricated 3D CYTOP Microfluidic Chips Enabling Super‐Resolution Live Imaging of Cell Behavior in Confined Microspaces

Advanced Materials Technologies, EarlyView.
Using two‐photon polymerization of SU‐8 together with mold processing allowed the creation of defect‐free, flexible 3D microfluidic structures with sub‐micrometer precision in CYTOP. The fabricated CYTOP microfluidic chips enabled super‐resolution imaging of cancer cells in the microchannels, clearly visualizing previously undetectable fine structural ...
Koji Sugioka, Mirai Hanzawa, Kotaro Obata, Sota Matsumoto, Masatoshi Takagi, Asako Sakaue‐Sawano, Asako Tosaki, Satoshi Shimozono, Felix Sima, Hiroyuki Kawano, Takuro Tojima, Daisuke Miyashiro, Kazunari Ozasa, Yasutaka Hanada, Godai Miyaji, Akihiko Nakano, Atsushi Miyawaki   +16 more
wiley   +1 more source

Regional heterogeneities of oligodendrocytes underlie biased Ranvier node spacing along single axons in sound localization circuit. [PDF]

Elife
Egawa R, Hiraga K, Matsui R, Watanabe D, Kuba H.   +4 more
europepmc   +1 more source

Wireless Power Transfer Modalities for Implantable Bioelectronics: Electromagnetic, Acoustic, and Magneto‐Dynamic Perspectives

Advanced Materials Technologies, EarlyView.
This review traces the evolution of wireless power transfer (WPT) for implantable medical devices, spanning electromagnetic, magnetoelectric, acoustic, and magneto‐dynamic systems. Quantitative comparisons of power, distance, and device scale highlight trade‐offs across modalities, while emerging hybrid mechanisms reveal strategies to overcome ...
Junyeop Kim, Yoonseok Park
wiley   +1 more source

Cortical white matter: no longer a silent partner. [PDF]

Front Neuroanat
Rockland KS, Rushmore RJ.
europepmc   +1 more source

Reviewer #2 (Public Review): Multiple Guidance Mechanisms Control Axon Growth to Generate Precise T-shaped Bifurcation during Dorsal Funiculus Development in the Spinal Cord

Bridget M Curran, Kelsey R Nickerson, Andrea R Yung, Lisa V Goodrich, Alexander Jaworski, Marc Tessier-Lavigne, Le Ma   +6 more
openalex   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

Advanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann, Theresa M. Wierschin, Stefanie Kretschmer, Banaja P. Dash, Aaron Held, Andrea Salzinger, Kevin Peikert, Anže Karlek, Hannes Glaß, Dajana Großmann, René Günther, Susanne Petri, Annekathrin Rödiger, David Brenner, Francisco Pan‐Montojo, Eleonora Aronica, Markus Kipp, Vitaly Zimyanin, Jared Sterneckert, Torsten Grehl, Noah D. Seebacher, Tobias M. Böckers, Alberto Catanese, Brian J. Wainger, Patrick Oeckl, Min Ae Lee‐Kirsch, Andreas Hermann   +26 more
wiley   +1 more source

Axonal Eif5a hypusination controls local translation and mitigates defects in FUS-ALS. [PDF]

Nat Neurosci
Piol D, Khalil B, Robberechts T, Killian T, Georgopoulou M, Partel G, Wouters D, Hecker N, Tziortzouda P, Verresen Y, Corthout N, Kint S, Vandereyken K, Van Damme P, Voet T, Davie K, Poovathingal S, Van Den Bosch L, Aerts S, Sifrim A, Da Cruz S.   +20 more
europepmc   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source

An epidermal membrane-associated periodic skeleton restricts endocytosis to stabilize neuron-epidermal attachment and preserve axons. [PDF]

Sci Adv
Coakley S, Bonacossa-Pereira I, Le D, Hilliard MA.   +3 more
europepmc   +1 more source

Long‐Term Effects of Xenotransplantation of Human Enteric Glia in an Immunocompetent Rat Model of Acute Brain Injury

Advanced Science, EarlyView.
Acute brain injuries are characterized by extensive tissue damage, resulting in debilitating deficits in patients. Despite considerable progress, cell‐based approaches have yet to identify an ideal candidate. This long‐term study explores the use of an untested cell source – human enteric glia – and a non‐invasive administration route – intranasal ...
Nina Colitti, Edwige Rice, Franck Desmoulin, Maylis Combeau, Mélissa Parny, Lorenne Robert, Etienne Buscail, Barbara Bournet, Nathalie Vergnolle, Isabelle Raymond‐Letron, Isabelle Loubinoux, Carla Cirillo   +11 more
wiley   +1 more source