Results 241 to 250 of about 448,604 (375)

Neural Circuits between Nodose Ganglion and Pulmonary Neuroendocrine Cells Regulate Lung Inflammatory Responses

Advanced Science, EarlyView.
TRPA1+αCGRP+ sensory neurons in the nodose ganglion detect external insults such as lipopolysaccharide (LPS) and interact directly with pulmonary neuroendocrine cells (PNECs), promoting their activation and proliferation. This neural‐epithelial interaction amplifies lung inflammation.
Jie Chen, Shitao Xie, Zhekai Lin, Caiqi Zhao, Rujia Tao, Yingying Ma, Xiaoyan Chen, Renlan Wu, Qingjian Han, Pengfei Sui, Sheng Wang, Hongbin Ji, Hai Song, Xiaoming Zhang, Yangang Sun, Yuanlin Song, Xiao Su   +16 more
wiley   +1 more source

Axonal structure-function relationships across experimental modalities. [PDF]

Imaging Neurosci (Camb)
Skoven CS, Andersson M, Torre MLB, Pizzolato M, Siebner HR, Dyrby TB.   +5 more
europepmc   +1 more source

Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization.

RNA: A publication of the RNA Society, 2011
Laura F. Gumy, G. Yeo, Y. C. Tung, Krishna H. Zivraj, Dianna E. Willis, G. Coppola, B. Lam, J. Twiss, C. Holt, J. Fawcett   +9 more
semanticscholar   +1 more source

Auditory Hair Cell Mechanotransduction Channels Dynamically Shape the Mechanical Properties of Their Membrane Environment

Advanced Science, EarlyView.
This work shows, for the first time, that the stereocilia membrane in cochlear hair cells is dynamically regulated by the mechanotransduction channel to impact the membrane mechanical properties. This work provides direct evidence that the opening and closing associated with the MET channel is regulating the membrane viscosity suggesting that the MET ...
Shefin S. George, Anthony J. Ricci
wiley   +1 more source

Repulsions instruct synaptic partner matching in an olfactory circuit. [PDF]

Nature
Li Z, Lyu C, Xu C, Hu Y, Luginbuhl DJ, Caspi-Lebovic AB, Priest JM, Özkan E, Luo L.   +8 more
europepmc   +1 more source

Axonal regeneration and development of de novo axons from distal dendrites of adult feline commissural interneurons after a proximal axotomy

, 2007
Keith K. Fenrich, Nicole Skelton, Victoria E. MacDermid, Claire Francesca Meehan, Stacey Armstrong, Monica Neuber‐Hess, P. K. Rose   +6 more
openalex   +1 more source

Nurr1 Orchestrates Claustrum Development and Functionality

Advanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan, Andrew G. Newman, Pauline Lange, Susanne Müller, Marco Foddis, Stefan Paul Koch, Philipp Böhm‐Sturm, Maron Mantwill, Carsten Finke, Penghui Deng, Melissa Long, Dietmar Schmitz, Victor Tarabykin   +12 more
wiley   +1 more source

CYFIP1 governs the development of cortical axons by modulating calcium availability. [PDF]

Nat Commun
Ricci C, Midroit MJ, Caicci F, Achsel T, Domínguez-Iturza N, Bagni C.   +5 more
europepmc   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Vesicular Rps6 Released by Astrocytes in an Experimental Model of AD Regulates Local Translation and Enhances Synaptic Integrity in Neurones. [PDF]

J Extracell Vesicles
Gamarra M, Cruz-Gambra A, Blanco-Urrejola M, González E, Azkargorta M, Elortza F, Falcón-Pérez JM, Baleriola J.   +7 more
europepmc   +1 more source