Results 191 to 200 of about 7,418 (226)

Calcium and the Mechanism of Axoplasmic Transport

1978
Using desheathed cat peroneal nerves in in vitro studies, Ca2+ was recently shown to be required to maintain axoplasmic transport. Calmodulin was also shown to be present in nerve and to participate in transport. These findings open up new possibilities for a better understanding of the underlying mechanism of transport. In the transport filament model,
S. Ochs, S.-Y. Chan, R. Worth
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The Direct Effects of Graded Axonal Compression on Axoplasm and Fast Axoplasmic Transport

Journal of Neuropathology and Experimental Neurology, 1992
The direct effects of mechanical compression on axoplasm and fast axoplasmic transport were studied by video-enhanced differential interference microscopy. Single axons, isolated from the squid, were compressed with 0.5, 5, 20, or 100 gram (g) weights placed over a 1 millimeter (mm) length of axon.
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Axoplasmic transport of muscarinic receptors

Nature, 1980
The reality of axoplasmic transport is widely accepted; various neutrotransmitters, enzymes, labelled proteins and peptides are known to move rapidly along the axons of different nerve fibres. In the terminals of sympathetic nerves, noradrenaline release is controlled by various regulatory mechanisms which imply the occurrence of presynaptic receptors.
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Inhibition of fast axoplasmic transport by acrylamide

Environmental Research, 1978
The effect of acrylamide on fast axoplasmic transport in the cat sciatic nerve was studied in vivo and in vitro by the technique of isotope injection. [14C]leucine was injected into the lumbar dorsal root ganglia. In cats fed daily doses of acrylamide over 1 to 4 weeks, the rate of transport was 286 mm/day compared with 424 mm/day in controls. In vitro
Thomas N. Chase, George A. Glaubiger, Roger L. Weir   +2 more
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Pharmacology and toxicology of axoplasmic transport

1984
The organized movement of cytoplasmic constituents is now recognized as a physiological process vital to the normal functioning of all cells. The importance of the ‘flow of nutrients’ for the well being of neurons and their innervated tissues was inferred as early as the mid-18th century (see quote from Prochaska, title heading).
J. Alejandro Donoso, Fred E. Samson
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RAPID AXOPLASMIC TRANSPORT IN DYSTROPHIC MICE

Journal of Neurochemistry, 1977
Abstract— Rapid axoplasmic transport was studied in dystrophic mice of the 129/ReJ‐dy strain. Proteins transported in vivo through α‐motoneurons of the sciatic nerve were labeled by injections of [3H] or [35S] amino acids into the ventral horn of the lumbar spinal cord.
Mclane, J A, Mcclure, W O
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Axoplasmic transport with velocities induced by pargyline

Journal of Neuroscience Research, 1980
AbstractThe axoplasmic transport of proteins in spinal motor neurons is altered by pargyline, a drug that causes increased release of monoamines. Two new peaks of transported protein were detected in the sciatic nerves of rats treated with pargyline (75 mg/kg/day ip for three days).
Danny F. Watson, Fred E. Samson, J. Alejandro Donoso, Robert E. O'Neill   +3 more
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Axoplasmic asymmetry at the node of Ranvier

Journal of Neurocytology, 1983
The previously described unilateral condensation of axoplasmic organelles at the node of Ranvier of large diameter fibres in spinal nerve roots has been confirmed in a single normal rabbit. The tendency for this phenomenon to occur on the proximal (neuronal) side of the node, as implied in previous studies, could not be supported by numerical analysis ...
Anthony Masone, Cedric S. Raine, Howard Finch   +2 more
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Slow axoplasmic transport: a fiction?

Journal of Theoretical Biology, 1985
Ribosomes have not been observed in axoplasm. This had led to the notions that the perikaryon is the only source of neuronal proteins and that the axoplasm is supplied by a (slow) transport mechanism. However, we question these two notions because they are unable to give an account of real neurones in accordance with the body of biological knowledge ...
ALVAREZ, J, TORRES, JC
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Axoplasmic flow in myelinated and unmyelinated nerves

Brain Research, 1977
[14C]Leucine was injected into the floor of the IVth ventricle of rabbits in order to label the axoplasmic flow of proteins in the efferent fibres of the vagus nerve. At intervals from 6 h to 180 days after injection, the rabbits were sacrificed and the cervical and abdominal vagus and recurrent laryngeal nerves removed.
M. Somerville, Walter G. Bradley
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