Results 31 to 40 of about 7,418 (226)

Nerve conduction models in myelinated and unmyelinated nerves based on three-dimensional electrostatic interaction

open access: yesNeural Regeneration Research, 2018
Until now, nerve conduction has been described on the basis of equivalent circuit model and cable theory, both of which supposed closed electric circuits spreading inside and outside the axoplasm.
Tetsuya Akaishi
doaj   +1 more source

Mechanical Surface Waves Accompany Action Potential Propagation [PDF]

open access: yes, 2014
Many studies have shown that a mechanical displacement of the axonal membrane accompanies the electrical pulse defining the Action Potential (AP). Despite a large and diverse body of experimental evidence, there is no theoretical consensus either for the
Hady, Ahmed El, Machta, Benjamin B.
core   +2 more sources

Schwann cell to axon transfer of ribosomes: toward a novel understanding of the role of glia in the nervous system [PDF]

open access: yes, 2008
Schwann cells play pivotal roles in the development and maintenance of the peripheral nervous system. Here, we show that intact sciatic nerve axons of mice contain a small population of ribosomes, which increases by several orders of magnitude when axons
Alvarez, J.   +4 more
core   +5 more sources

Alphaherpesviruses and the Cytoskeleton in Neuronal Infections

open access: yesViruses, 2011
Following infection of exposed peripheral tissues, neurotropic alphaherpesviruses invade nerve endings and deposit their DNA genomes into the nuclei of neurons resident in ganglia of the peripheral nervous system.
Gregory A. Smith   +2 more
doaj   +1 more source

The ultrastructure of nerve axoplasm [PDF]

open access: yesProceedings of the Royal Society of London. Series B - Biological Sciences, 1937
In previous papers on the micellar organization of the nerve fibre, attention has been directed almost entirely to the lipoid-containing sheaths. Polarized light and X-ray diffraction studies have emphasized the similarity of the architecture of these structures over a wide range of animal forms, from the highly myelinated nerves of vertebrates to the ...
Richard S. Bear   +2 more
openaire   +2 more sources

Effects of topiramate on the ultrastructure of synaptic endings in the hippocampal CA1 and CA3 sectors in the rat experimental model of febrile seizures: the first electron microscopy report

open access: yesFolia Neuropathologica, 2019
The present study aimed at exploring a potentially neuroprotective effect of topiramate (TPM), one of the most commonly used newer-generation, broad-spectrum, antiepileptic drugs against ultrastructural damage of hippocampal synaptic endings in the ...
Joanna Łotowska   +5 more
doaj   +1 more source

Regulation of Axonal Transport by Protein Kinases [PDF]

open access: yes, 2015
The intracellular transport of organelles, proteins, lipids, and RNA along the axon is essential for neuronal function and survival. This process, called axonal transport, is mediated by two classes of ATP-dependent motors, kinesins, and cytoplasmic ...
Gibbs, KL, Greensmith, L, Schiavo, G
core   +1 more source

A TSPO ligand is protective in a mouse model of multiple sclerosis. [PDF]

open access: yes, 2013
Local production of neurosteroids such as progesterone and allopregnanolone confers neuroprotection in central nervous system (CNS) inflammatory diseases.
Chechneva, Olga V   +5 more
core   +2 more sources

Neuropathogenic Forms of Huntingtin and Androgen Receptor Inhibit Fast Axonal Transport [PDF]

open access: yes, 2003
Huntington's and Kennedy's disease are autosomal dominant neurodegenerative diseases caused by pathogenic expansion of polyglutamine tracts. Expansion of glutamine repeats must in some way confer a gain of pathological function that disrupts an essential
Babcock, Alyssa   +10 more
core   +1 more source

Regulation of retinal axon growth by secreted Vax1 homeodomain protein

open access: yeseLife, 2014
Retinal ganglion cell (RGC) axons of binocular animals cross the midline at the optic chiasm (OC) to grow toward their synaptic targets in the contralateral brain. Ventral anterior homeobox 1 (Vax1) plays an essential role in the development of the OC by
Namsuk Kim   +9 more
doaj   +1 more source

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