Results 41 to 50 of about 7,418 (226)

On axoplasmic pressure waves and their possible role in nerve impulse propagation

, 2010
It is suggested that the propagation of the action potential is accompanied by an axoplasmic pressure pulse propagating in the axoplasm along the axon length.
Rvachev, Marat M.
core   +1 more source

Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS. [PDF]

, 2010
Many mutations confer one or more toxic function(s) on copper/zinc superoxide dismutase 1 (SOD1) that impair motor neuron viability and cause familial amyotrophic lateral sclerosis (FALS).
A Durazo, A Gruzman, A Kerman, A Tiwari, AG Estévez, AK Svensson, AL Ström, Benjamin A Fontaine, C Vande Velde, Daryl A Bosco, DE Bredesen, Diane McKenna-Yasek, E Kabashi, F Gros-Louis, Francois Gros-Louis, G Morfini, G Morfini, GA Morfini, GA Morfini, Gerardo Morfini, HN Liu, Holly Goolsby, Jean-Pierre Julien, Jeffrey N Agar, JF Collard, JS Beckman, JS Valentine, KJ De Vos, KS Molnar, L Banci, L Munoz, L Wang, LI Bruijn, LJ Hayward, LR Fischer, M Chattopadhyay, M Prudencio, M Urushitani, M Urushitani, M Watanabe, MA Fabian, Matthew P Frosch, MJ Lindberg, N Fujiwara, N Murat Karabacak, N Shibata, N Shibata, Nathan Lemay, P Pasinelli, Piera Pasinelli, PN Valdmanis, Q Wang, R Rakhit, R Rakhit, R Rakhit, R Tandan, Robert H Brown, RW Strange, SA Ezzi, Scott T Brady, ST Brady, ST Brady, TL Williamson, Y Furukawa, Yuyu Song   +64 more
core   +2 more sources

Mitochondrial Transport and Turnover in the Pathogenesis of Amyotrophic Lateral Sclerosis

Biology, 2019
Neurons are high-energy consuming cells, heavily dependent on mitochondria for ATP generation and calcium buffering. These mitochondrial functions are particularly critical at specific cellular sites, where ionic currents impose a large energetic burden,
Veronica Granatiero, Giovanni Manfredi
doaj   +1 more source

Modelling selective activation of small myelinated nerve fibres using a monopolar point electrode [PDF]

, 1995
The aim of this study is to investigate theoretically the possibility for activation of small myelinated nerve fibres without activating larger ones when stimulating a nerve fibre bundle using a monopolar point electrode.
Debruyne, F.M.J., Holsheimer, J., Rijkhoff, N.J.M., Rijkhoff, N.J.M., Wijkstra, H.   +4 more
core   +3 more sources

Allograft pretreatment for the repair of sciatic nerve defects: green tea polyphenols versus radiation

Neural Regeneration Research, 2015
Pretreatment of nerve allografts by exposure to irradiation or green tea polyphenols can eliminate neuroimmunogenicity, inhibit early immunological rejection, encourage nerve regeneration and functional recovery, improve tissue preservation, and minimize
Sheng-hu Zhou, Ping Zhen, Shen-song Li, Xiao-yan Liang, Ming-xuan Gao, Qi Tian, Xu-sheng Li   +6 more
doaj   +1 more source

Increased expression of matrix metalloproteinase-9 in patients with temporal lobe epilepsy [PDF]

, 2014
Aim: The molecular mechanism of epileptogenesis in temporal lobe epilepsy is still unclear. Experimental studies have suggested that matrix metalloproteinases have important roles in this process, but human studies are limited.
Acar, Feridun, Acar, Göksemin, Demir, R., Tanriover, G.   +3 more
core   +1 more source

Estimation of presynaptic calcium currents and endogenous calcium buffers at the frog neuromuscular junction with two different calcium fluorescent dyes

Frontiers in Synaptic Neuroscience, 2015
At the frog neuromuscular junction, under physiological conditions, the direct measurement of calcium currents and of the concentration of intracellular calcium buffers—which determine the kinetics of calcium concentration and neurotransmitter release ...
Dmitry eSamigullin, Dmitry eSamigullin, Dmitry eSamigullin, Nijaz eFatikhov, Eduard eKhaziev, Eduard eKhaziev, Andrei eSkorinkin, Andrei eSkorinkin, Evgeny eNikolsky, Evgeny eNikolsky, Evgeny eNikolsky, Ellya eBukharaeva, Ellya eBukharaeva   +12 more
doaj   +1 more source

Alterations in Sub-Axonal Architecture Between Normal Aging and Parkinson’s Diseased Human Brains Using Label-Free Cryogenic X-ray Nanotomography

Frontiers in Neuroscience, 2020
Gaining insight to pathologically relevant processes in continuous volumes of unstained brain tissue is important for a better understanding of neurological diseases.
Hung Tri Tran, Esther H. R. Tsai, Amanda J. Lewis, Tim Moors, J. G. J. M. Bol, Iman Rostami, Ana Diaz, Allert J. Jonker, Manuel Guizar-Sicairos, Joerg Raabe, Henning Stahlberg, Wilma D. J. van de Berg, Mirko Holler, Sarah H. Shahmoradian   +13 more
doaj   +1 more source

Squid giant axon contains neurofilament protein mRNA but does not synthesize neurofilament proteins [PDF]

, 2016
Author Posting. © The Author(s), 2016. This is the author's version of the work. It is posted here by permission of Springer for personal use, not for redistribution. The definitive version was published in Cellular and Molecular Neurobiology 37 (2017):
Chin, Hemin, Gainer, Harold, House, Shirley, Kim, Dong Sun, Pant, Harish C.   +4 more
core   +1 more source

Investigating the role of SARM1 in central nervous system

Ibrain, EarlyView.
Sterile‐α and Toll/interleukin 1 receptor (TIR) motif‐containing protein 1 (SARM1) is a pivotal molecule that has garnered extensive attention in neuroscience. As an intracellular molecule, SARM1 possesses various crucial biological functions in the nervous system.
Junjie Wang, Yuhang Shi, Jinglei Tian, Liming Tang, Fang Cao   +4 more
wiley   +1 more source