Results 61 to 70 of about 7,418 (226)
Purpose: To evaluate the ultrastructure of the choriocapillaris, retina and optic nerve (ON) in citicoline-treated versus non-treated rabbits at the late time point after inducing non-infectious anterior and intermediate uveitis.
V. Ulianov, I. Horianova, N. Molchaniuk
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While the peripheral nervous system has regenerative ability, restoration of sufficient function remains a challenge. Vimentin has been shown to be localized in axonal growth fronts and associated with nerve regeneration, including myelination ...
Travis B Sullivan+8 more
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Regulation of motor proteins, axonal transport deficits and adult-onset neurodegenerative diseases [PDF]
© The Author(s), 2017. This is the author's version of the work and is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Neurobiology of Disease 105 (2017): 273-282, doi:10.1016/j.nbd.2017.04.
Brady, Scott T., Morfini, Gerardo A.
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Colloid osmotic parameterization and measurement of subcellular crowding [PDF]
© The Author(s), 2019. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Mitchison, T. J. (2019).
Mitchison, Timothy J.
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Abstract Purpose To compare MR axon radius estimation in human white matter using a multiband spiral sequence combined with field monitoring to the current state‐of‐the‐art echo‐planar imaging (EPI)‐based approach. Methods A custom multiband spiral sequence was used for diffusion‐weighted imaging at ultra‐high b$$ b $$‐values.
Marten Veldmann+6 more
wiley +1 more source
Amyotrophic lateral sclerosis (ALS) is characterized by massive loss of motor neurons. Data from ALS patients and experimental models indicate that mitochondria are severely damaged within dying or spared motor neurons.
Gianfranco eNatale+7 more
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Mitochondrial plasticity and synaptic plasticity crosstalk; in health and Alzheimer's disease
The mechanism of mitochondrial transport within the neuron is mediated on the cytoskeleton. The retrograde (−) motion deployed the movement of mitochondria toward the cell body with the help of dynein, TRAK1/2, and Mrio1/2 protein. While anterograde (+) motion causes the movement toward the axon with the assistance of kinesin, TRAK1/2, and Miro1/2 ...
Fatemeh Sayehmiri+8 more
wiley +1 more source
Slow axoplasmic transport under scrutiny [PDF]
The origin of axoplasmic proteins is central for the biology of axons. For over fifty years axons have been considered unable to synthesize proteins and that cell bodies supply them with proteins by a slow transport mechanism. To allow for prolonged transport times, proteins were assumed to be stable, i.e., not degraded in axons. These are now textbook
Court, Felipe A, Álvarez, Jaime
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The unusual microtubule polarity in teleost retinal pigment epithelial cells. [PDF]
In cells of the teleost retinal pigment epithelium (RPE), melanin granules disperse into the RPE cells long apical projections in response to light onset, and aggregate toward the base of the RPE cell in response to dark onset.
BURNSIDE, Beth, Troutt, L
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Maintenance and degradation of proteins in intact and severed axons: Implications for the mechanism of long-term survival of anucleate crayfish axons [PDF]
Protein maintenance and degradation are examined in the severed distal (anucleate) portions of crayfish medial giant axons (MGAs), which remain viable for over 7 months following axotomy.
Bittner, George D.+2 more
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