Mitigation of nociception via transganglionic degenerative atrophy: possible mechanism of vinpocetine-induced blockade of retrograde axoplasmic transport [PDF]
I Sverige har ett förväntat ökande gap mellan tillgängliga resurser och ökade behandlingsmöjligheter satt fokus på evidensbaserad prioritering. Problem har emellertid konstaterats inom områden med svag evidensgrund och oklar eller kontroversiell ...
Csillik, Bertalan +4 more
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Effect of vinpocetine on retrograde axoplasmic transport [PDF]
Många avancerade och komplexa system används idag run-tom i världen och flera av dem är väldigt viktiga att de fungerar och fortsätter göra det. För att inte förstöra dessa system så kan en dry-run användas om någonting behöver uppdateras eller ändras ...
Knyihár-Csillik, Erzsébet +6 more
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The Progress in Exploratory Studies of Peripheral Blood Single Nucleated Cells as Seed Cells in Peripheral Nerve Repair. [PDF]
Peripheral nerve injury (PNI) represents a prevalent clinical condition, often resulting from mechanical trauma or tumor resection, which frequently induces persistent sensory deficits, motor impairment, neuropathic pain, or paralysis. Consequently, substantial socioeconomic burdens are imposed on affected individuals.
Chen Y, Wen Y, Zhang M, Nie J, Sun G.
europepmc +2 more sources
We investigated the occurrence of mesenchymal stem cell (MSC)-derived exosome uptake and retrograde transport at peripheral nerve endings using bone marrow MSCs (bMSCs) transduced with recombinant CD63-green fluorescent protein (GFP) lentiviral plasmid ...
Rui Ren +12 more
doaj +1 more source
Pathological classification of equine recurrent laryngeal neuropathy [PDF]
Recurrent Laryngeal Neuropathy (RLN) is a highly prevalent and predominantly left‐sided, degenerative disorder of the recurrent laryngeal nerves (RLn) of tall horses, that causes inspiratory stridor at exercise because of intrinsic laryngeal muscle ...
Draper, A C E, Piercy, R J
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Nicotinamide and WLDS Act Together to Prevent Neurodegeneration in Glaucoma
Glaucoma is a complex neurodegenerative disease characterized by progressive visual dysfunction leading to vision loss. Retinal ganglion cells are the primary affected neuronal population, with a critical insult damaging their axons in the optic nerve ...
Simon W. M. John +6 more
doaj +1 more source
Tangles, toxicity, and tau secretion in AD – new approaches to a vexing problem
When the microtubule-associated protein tau is not bound to axonal microtubules (MTs), it becomes hyperphosphorylated and vulnerable to proteolytic cleavage and other changes typically seen in the hallmark tau deposits (neurofibrillary tangles) of tau ...
Kerry eGendreau, Garth F Hall
doaj +1 more source
The amyloid precursor protein of Alzheimer’s disease clusters at the organelle/microtubule interface on organelles that bind microtubules in an ATP dependent manner [PDF]
© The Author(s), 2016. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in PLoS One 11 (2016): e0147808, doi:10.1371/journal.pone.0147808.The amyloid precursor protein (APP) is
Conaty, Eliza A. +6 more
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Analysis of optic disc damage by optical coherence tomography in terms of therapy in non-arteritic anterior ischemic optic neuropathy [PDF]
K
Balogh, Zsuzsa +7 more
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Rescue of tau-induced synaptic transmission pathology by paclitaxel
Behavioral and electrophysiological studies of Alzheimer’s disease (AD) and other tauopathies have revealed that the onset of cognitive decline correlates better with synaptic dysfunctions than with hallmark pathologies such as extracellular amyloid-β ...
Hdas eErez, Or A Shemesh, Micha E. Spira
doaj +1 more source

