Results 51 to 60 of about 2,127,716 (198)
Abstract Objective Little is known about amyotrophic lateral sclerosis (ALS)‐nonspecific cognitive deficits – most notably memory disturbance – and their biological underpinnings. We investigated the associations of the Alzheimer's disease (AD) genetic risk factor APOE and cerebrospinal fluid (CSF) biomarkers Aβ and tau proteins with cognitive and ...
Alessio Maranzano+22 more
wiley +1 more source
Some postmortem studies on patients with amyotrophic lateral sclerosis (ALS) disclosed tau pathology in the central nervous system. Since deregulated cyclin‐dependent kinase 5 (Cdk5) activity is closely correlated with tau pathology, Cdk5 inhibition in the ALS mouse model was performed in this study. Intrathecal injection of AAV9‐Cdk5‐shRNA in SOD1G93A
Ahwon Kim+2 more
wiley +1 more source
Knockdown of the lncRNA H19 significantly promotes recovery from traumatic brain injury (TBI) in mice, as evidenced by reduced neuroinflammation, attenuated tissue damage including gray and white matter, and improved neurological function. This neuroprotective effect was significantly mediated by activation of the Nrf2/HO‐1 signaling pathway, revealing
Qiankang Chen+10 more
wiley +1 more source
This study identifies the roles of TREK1 and TREK2 in prediabetic neuropathic pain and investigates the modulation of Sortilin within these channels. It suggests that Sortilin overexpression leads to a decrease in TREK1 and TREK2 expression, which in turn contributes to the modulation of neural hyperexcitability and nociceptive hypersensitivity in rats
Wei Sun+8 more
wiley +1 more source
The role of autophagy in odontogenesis, dental implant surgery, periapical and periodontal diseases
Abstract Autophagy is a cellular process that is evolutionarily conserved, involving the sequestration of damaged organelles and proteins into autophagic vesicles, which subsequently fuse with lysosomes for degradation. Autophagy controls the development of many diseases by influencing apoptosis, inflammation, the immune response and different cellular
Sevinç İnan, Emre Barış
wiley +1 more source
Research Progress of Nerve Mobilization in Basic and Clinical Rehabilitation
The purpose of this paper is to provide a systematic review of the literature concerning the theoretical basis, research advance and clinical status of nerve mobilization(NM)in various neuro-musculoskeletal conditions, which may provide important ...
Shuo LUAN+4 more
doaj
Rapid Axoplasmic Transport of Tyrosine Hydroxylase in Relation to Other Cytoplasmic Constituents [PDF]
Bevyn Jarrott, L. B. Geffen
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Biosynthesis and axoplasmic transport of neurophysins in the hypothalamo-neurohypophysial system of Rana pipiens [PDF]
AC Chang, HD Dellmann
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Rapid onset of neuronal death induced by blockade of either axoplasmic transport or action potentials in afferent fibers during brain development [PDF]
Marina Catsicas+2 more
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Vibration‐induced disruption of retrograde axoplasmic transport in peripheral nerve [PDF]
Ji‐Geng Yan+4 more
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