Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS. [PDF]
, 2010 Many mutations confer one or more toxic function(s) on copper/zinc superoxide dismutase 1 (SOD1) that impair motor neuron viability and cause familial amyotrophic lateral sclerosis (FALS).
A Durazo +64 more
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Directional instability of microtubule transport in the presence of kinesin and dynein, two opposite polarity motor proteins. [PDF]
, 1992 Kinesin and dynein are motor proteins that move in opposite directions along microtubules. In this study, we examine the consequences of having kinesin and dynein (ciliary outer arm or cytoplasmic) bound to glass surfaces interacting with the same ...
Brown, D, Malik, F, Vale, RD
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Research Progress of Nerve Mobilization in Basic and Clinical Rehabilitation
康复学报, 2019 The purpose of this paper is to provide a systematic review of the literature concerning the theoretical basis, research advance and clinical status of nerve mobilization(NM)in various neuro-musculoskeletal conditions, which may provide important ...
Shuo LUAN +4 more
doaj
Glaucoma: the retina and beyond [PDF]
, 2016 Over 60 million people worldwide are diagnosed with glaucomatous optic neuropathy, which is estimated to be responsible for 8.4 million cases of irreversible blindness globally.
Cordeiro, MF +4 more
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High voltage electron microscopy studies of axoplasmic transport in neurons: a possible regulatory role for divalent cations. [PDF]
, 1982 Mark E. Stearns
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Radial optic neurotomy: a new surgical approach for glaucoma treatment? [PDF]
, 2012 Glaucoma is a leading cause of blindness worldwide, characterised by specific visual field defects due to the degeneration of retinal ganglion cells and damage to the optic nerve head (ONH).
Belforte, Nicolás Adalberto +1 more
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Endogenous axoplasmic proteins and proteins containing nuclear localization signal sequences use the retrograde axonal transport/nuclear import pathway in Aplysia neurons [PDF]
, 1993 Robert Schmied +4 more
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Changes in the cholinergic system of rat sciatic nerve and skeletal muscle following suspension induced disuse [PDF]
Muscle disused induced changes in the cholinergic system of sciatic nerve, slow twitch soleus (SOL) and fast twitch extensor digitorum longus (EDL) muscle were studied in rats. Rats with hindlimbs suspended for 2 to 3 weeks showed marked elevation in the
Dettbarn, W. D. +2 more
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