Results 71 to 80 of about 5,363,495 (332)
The aim of this study was to identify new compounds active againstPlasmodium falciparum based on our previous research carried out on 3-phenylquinoxaline-2-carbonitrile 1,4-di-N-oxide derivatives.
Antonio Monge +10 more
doaj +1 more source
The factors that affect the kinetics of the aza-Bergman cyclization of aza-enediynes (C,N-dialkynyl imines) have not previously been elucidated. Here we report our kinetic studies of the aza-Bergman reactions of a series of 6-triisopropylsilyl and 6 ...
Dalip Kumar (467427) +2 more
core +1 more source
Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro +6 more
wiley +1 more source
Phenylsulfonylacetonitrile (1) when reacted with α,β-unsaturated nitriles (2a,b) and/or 2-hydroxynaphthaldehyde yields pyridine derivatives (3a,b) and / or the iminochromene derivative (4) respectively.
M. E. A. Zaki +2 more
doaj +1 more source
Ab Initio Investigation of the 3-Aza-Cope Reaction
The energies of reaction and activation for three archetypal aliphatic 3-aza-Cope reactions have been investigated by MP4/6-31G*//MP2/6-31G* calculations.
Michael A. Walters (486126)
core +1 more source
Objective The objective of this study was to evaluate the real‐world effectiveness and safety of secukinumab in giant cell arteritis (GCA) patients. Methods This multicentre retrospective study included patients with GCA who received secukinumab at 14 Italian centres with at least 6 months of follow‐up.
Luca Iorio +29 more
wiley +1 more source
Chemo- and Stereoselective Reduction of Polyfunctional Carbonyl Compounds by Mucor rouxii
Several polyfunctional carbonyl compounds, such as α- and β-ketoesters, were chemo- and stereoselectively reduced by Mucor rouxii cultures in water and in organic solvents.
Constanza P. Mangone +3 more
doaj +1 more source
High‐Efficiency Deep Blue Single‐Gaussian Europium(II) Emitters and Their Emitter‐Host Interactions
Crown‐ether ligands and carborate anions enable vacuum‐processable Eu(II) emitters with efficient single‐Gaussian deep‐blue luminescence. Combined photophysical and computational analyses reveal that excited‐electron confinement and steric shielding of the europium center jointly govern compatibility with OLED host materials, establishing molecular ...
Mahmoud Soleimani +8 more
wiley +1 more source
Immunomodulatory Effect of Aza-Spirocyclic Frameworks
Background: Immunomodulators play a central role in the treatment of cancer and immune-mediated disorders. Small-molecule immunomodulators are particularly attractive due to their structural diversity, pharmacological versatility, and ...
Anjali Prajapati +3 more
doaj +1 more source
Two New Flavonol Glycosides from Sarcopyramis bodinieri var. delicate
Detailed chemical investigation of the herb Sarcopyramis bodinieri var. delicate resulted in the isolation of two new flavonol glycosides, namely, isorhamnetin-3-O-(6′′-OE- feruloyl)-β-D-glucopyranoside (1) and isorhamnetin-3-O-(6′â ...
Yan Qiu +3 more
doaj +1 more source

