Results 91 to 100 of about 76,298 (277)

Expert Perspective: Toward Treat‐to‐Target Management in Adult Idiopathic Inflammatory Myopathies

Arthritis &Rheumatology, Accepted Article.
Treat‐to‐target (T2T) has transformed the management of several rheumatic diseases through predefined therapeutic goals, structured disease assessment, and timely treatment adjustment. Despite major advances in the understanding and treatment of idiopathic inflammatory myopathies (IIM), a formal T2T framework for adult IIM has not yet been established.
Shiri Keret, Nantakarn Pongtarakulpanit, Rohit Aggarwal   +2 more
wiley   +1 more source

Azathioprine in autologous serum skin test positive chronic urticaria: A case-control study in a tertiary care hospital of eastern India

Indian Dermatology Online Journal, 2015
Context: Urticaria, also referred to as hives or wheals is a common and distinctive reaction pattern characterized by spontaneous eruption of wheals.
Dulal Chandra Bhanja, Loknath Ghoshal, Sudip Das, Suchibrata Das, Alok Kumar Roy   +4 more
doaj   +1 more source

Azathioprine hypersensitivity mimicking Goodpasture's syndrome.

, 1994
Side effects due to azathioprine (the nitroimidazole derivative of 6-mercaptopurine) can be classified as toxic (myelosuppression, hepatotoxicity) and idiosyncratic (fever, rigors, arthralgias, pneumonitis, and gastrointestinal symptoms). While the toxic
Krapf R, Schmidl M, Stetter M
core   +1 more source

Oral vancomycin solution is superior to capsule in inducing clinical biomarker and endoscopic remission in children with atypical ulcerative colitis

British Journal of Clinical Pharmacology, EarlyView.
Aims Atypical colitis (presenting reverse gradient colitis, backwash ileitis or rectal sparing) is associated with primary sclerosing cholangitis–ulcerative colitis (PSC). Oral vancomycin has been used to manage paediatric atypical colitis with/without confirmed PSC. Different preparations had shown different efficacy.
Laura Räisänen, Fariha Balouch, Claire Reilly, Christopher Burgess, Peter Lewindon   +4 more
wiley   +1 more source

Current evidence and insights on single vs. double dose of basiliximab in adult solid organ transplant recipients: A systematic review

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this systematic review was to assess all available clinical data regarding the use of a single dose of basiliximab in solid organ transplantation compared to the standard double dosage, with particular interest in efficacy, safety and cost‐savings.
Alessio Provenzani, Braidon A. Lape, Anneliese M. Harp, Victoria Weisbrod, Lavinia Piazza   +4 more
wiley   +1 more source

Case Report - Azathioprine-induced shock: An uncommon, unpredictable and potentially fatal adverse effect of azathioprine [PDF]

, 2007
A 60 year-old male was initiated on azathioprine 50 mg/day for airborne contact dermatitis. As the patient showed a satisfactory response to this initial therapy, azathioprine dose was escalated to 100 mg/day after two weeks. However, the patient started
Pise, Gajanan A, Vetrichevvel, TP, Thappa, Devinder Mohan   +2 more
core   +1 more source

Effect of conversion from azathioprine to mycophenolate mofetil on renal function in stable kidney transplant recipients

Turkish Journal of Internal Medicine, 2019
Aim: This study investigated the effect of mycophenolate mofetil (MPA) treatment instead of azathioprine (AZA) on renal function after kidney transplantation.
Mehmet Usta, Yavuz Ayar, Alparslan Ersoy
doaj   +1 more source

Experts opinion on the practical use of azathioprine and 6-mercaptopurine in inflammatory bowel disease [PDF]

, 2016
The relevance of azathioprine and 6-mercaptopurine therapy in inflammatory bowel disease, Crohn's disease, and ulcerative colitis, has been challenged in recent publications.
Kessler-Brondolo, Vera, Seibold, F., Rogler, Gerhard, Juillerat, P., Mottet, Christian, Froehlich, Florian, Rogler, G., Seibold, Frank, Schoepfer, A.M., Froehlich, F., Michetti, P., Cosnes, Jacques, Vavricka, S.R., Juillerat, Pascal, Michetti, Pierre, Cosnes, J., Vavricka, Stephan R, Schoepfer, Alain M, Mottet, C., Kessler-Brondolo, V.   +19 more
core   +2 more sources

Precision medicine in paediatrics: Progress and priorities

British Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain, Claire Booth, Joseph F. Standing, Charlotte I. S. Barker   +3 more
wiley   +1 more source

Is breastfeeding safe with azathioprine?

, 2011
Background Azathioprine is commonly used as an immunosuppressant during pregnancy in the management of various conditions such as connective tissue disorders, inflammatory bowel disease and pregnant women with organ transplant.
Andrew Currie, Mandeep Singh, Jan Qualie, Manjiri M Khare, Edmund S Howarth   +4 more
core   +1 more source