Results 131 to 140 of about 76,298 (277)

Intersection of systemic lupus erythematosus and autoimmune thyroid disease: Shared pathophysiology, epidemiology, diagnosis, and management

Rheumatology &Autoimmunity, EarlyView.
A proposed mechanistic framework of systemic lupus erythematosus (SLE) and autoimmune thyroid disease (AITD) pathogenesis. In Stage 1, genetically susceptible individuals harbor risk variants within major histocompatibility complex (HLA) and non‐HLA loci that impair central and peripheral immune tolerance mechanisms within the thymic and peripheral ...
Elisa Elisa, Awalia Awalia, Deasy Ardiany, Henry Sutanto   +3 more
wiley   +1 more source

Contemporary Fibrotic Interstitial Lung Disease Outcomes: A Multicentre National Cohort Study

Respirology, EarlyView.
This study determined contemporary transplant‐free survival in fibrotic interstitial lung disease (ILD), identified baseline factors associated with death or transplant, and assessed performance of the ILD‐GAP (Gender, Age, Physiology) index in a contemporary cohort.
Tyler Pitre, Christopher J. Ryerson, Shaun Ong, Kerri A. Johannson, Deborah Assayag, Veronica Marcoux, Martin Kolb, Helene Manganas, Daniel‐Costin Marinescu, Jolene H. Fisher   +9 more
wiley   +1 more source

Contemporary Concise Review 2025: Interstitial Lung Disease

Respirology, EarlyView.
ABSTRACT Multidisciplinary discussion remains the cornerstone of ILD diagnosis and management, with recent advances further strengthening the integration of clinical, radiological, pathological, and molecular information. Updated ILD nomenclature and classification better align disease terminology with underlying morphology and pathobiology.
Tonia Magrì, Luca Richeldi
wiley   +1 more source

Assessment of Major Adverse Cardiovascular Event Across Diverse Racial Groups of Psoriasis Patients on Biologic Therapy: A Retrospective Cohort Study

The Journal of Dermatology, EarlyView.
ABSTRACT Psoriasis is associated with an increased risk of major adverse cardiovascular events (MACE), and biologic therapy may reduce this risk by targeting systemic inflammation. However, limited data exist on whether long term MACE risk differs by biologic class or across racial groups. We conducted a retrospective cohort study to assess the risk of
Chunghwan Ro, Ana Ormaza Vera, Waleed Adawi, Clinton W. Enos   +3 more
wiley   +1 more source

Azathioprine Hypersensitivity Syndrome – Two Case Reports of Autoimmune Bullous Dermatoses

Azathioprine is a widely used immunosuppressant for autoimmune bullous dermatoses, valued for its steroid-sparing properties. However, it can rarely precipitate azathioprine hypersensitivity syndrome, an idiosyncratic reaction presenting with fever ...
Svetlana Popadić, Iva Maširević Mudrić, Marko Demenj, Anđela Kovčić, Branislav Lekić   +4 more
core   +1 more source

Diagnostic Delay in Eosinophilic Granulomatosis With Polyangiitis: Clinical Predictors and Implications for Earlier Recognition

Allergy, EarlyView.
This study aimed to assess diagnostic delay among patients with eosinophilic granulomatosis with polyangiitis (EGPA) and identify clinical characteristics associated with delayed recognition. EGPA diagnosis was delayed by nearly five years from symptom onset in this single‐center cohort.
Vani Mulkareddy, Kalena Liu, Shreya Mandloi, Kelsey Limage, Samuel R. Shing, Gurston G. Nyquist, Jessica Most, David Kennedy, Elina Toskala, Damaris Pena‐Evertz   +9 more
wiley   +1 more source

Effectiveness of Sulfasalazine Therapy Following Mesalazine Treatment Failure in Children with Ulcerative Colitis. [PDF]

Pediatr Gastroenterol Hepatol Nutr
Ruška P, Doder I, Pavić AM, Mišak Z, Kolaček S, Hojsak I.   +5 more
europepmc   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

Endoscopic Activity Prediction in Ulcerative Colitis Using Hemogram-Derived Inflammatory Indices: Impact of Azathioprine Use on Diagnostic Performance. [PDF]

J Clin Med
Kaya M, Evren G, Durak İ, Düzenli T, Köseoğlu H, Sadeçolak M.   +5 more
europepmc   +1 more source

Opsoclonus‐Myoclonus‐Ataxia Revealing Underlying Neuromyelitis Optica Spectrum Disorder

Movement Disorders Clinical Practice, EarlyView.
Ana Silvia Sobreira Lima Verde, Flávia de Paiva Santos Rolim, Amanda Vale Catunda, José Orlando Ferreira Tomé Filho, Milena Sales Pitombeira, Fernanda Martins Maia Carvalho, Paula Camila Alves de Assis Pereira Matos   +6 more
wiley   +1 more source