Results 131 to 140 of about 71,298 (290)

Azathioprine dose escalation in inflammatory bowel disease

, 2004
The definitive version is available at www.blackwell-synergy.comBackground: Forty per cent of patients with inflammatory bowel disease fail to respond to standard dose azathioprine (2 mg/kg/day).
Kamm, M., Rayner, C., Emmanuel, A., Hart, A., Hayward, C.   +4 more
core   +1 more source

Voclosporin‐induced gingival enlargement: A case report

Clinical Advances in Periodontics, EarlyView.
Abstract Background Drug‐influenced gingival enlargement (DIGE) is a recognized adverse effect of certain medications, particularly immunosuppressants like cyclosporin and tacrolimus. However, there have been no documented cases of DIGE associated with voclosporin, a newer calcineurin inhibitor used primarily to treat lupus nephritis.
Francesca Racca, Jessica M. Greco, Dimitris N. Tatakis   +2 more
wiley   +1 more source

Azathioprine treatment in systemic Lupus Erythematosus: a double edged sword

, 2015
Extremely severe pancytopenia induced by low dosage of azathioprine in systemic lupus erythematosus patients is rare. A 40-year-old Chinese female was diagnosed with systemic lupus erythematosus.
Farah Nadhirah
core   +2 more sources

Surgical management of persistent gingival recession after sepsis‐associated gingival necrosis in a patient with systemic lupus erythematosus: A case report

Clinical Advances in Periodontics, EarlyView.
Abstract Background Sepsis‐associated gingival necrosis is an uncommon oral manifestation that may result in extensive gingival recession after the resolution of the acute phase. Methods This report presents the 2‐year follow‐up of periodontal management in a 38‐year‐old woman with systemic lupus erythematosus, who developed septic shock accompanied by
Risako Mikami, Koji Mizutani, Ruriko Mizuno, Yuji Kabasawa, Koichiro Matsuo   +4 more
wiley   +1 more source

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

Food Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso, A. M. Abd El‐Aty, Kwaku Amoah, Xianghong Ju   +3 more
wiley   +1 more source

Applying Machine Learning Models to Predict Medication Nonadherence in Crohn’s Disease Maintenance Therapy

Patient Preference and Adherence, 2020
Lei Wang,1,* Rong Fan,1,* Chen Zhang,1 Liwen Hong,1 Tianyu Zhang,1 Ying Chen,2 Kai Liu,2 Zhengting Wang,1 Jie Zhong1 1Department of Gastroenterology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People’s Republic of ...
Wang L, Fan R, Zhang C, Hong L, Zhang T, Chen Y, Liu K, Wang Z, Zhong J   +8 more
doaj  

Successful Treatment of Amegakaryocytic Thrombocytopenia with Azathioprine

, 2011
Acquired amegakaryocytic thrombocytopenia (AAMT) is an entity characterized by severe thrombocytopenia with a significantly reduced number of megakaryocytes in the bone marrow. AAMT is rare and poorly defined.
Tzung-Chih Tang, Hung Chang
core   +1 more source

Infliximab, azathioprine, or combination therapy for Crohn's disease

, 2010
BACKGROUND: The comparative efficacy and safety of infliximab and azathioprine therapy alone or in combination for Crohn's disease are unknown. METHODS: In this randomized, double-blind trial, we evaluated the efficacy of infliximab monotherapy ...
Sandborn, W.J. (William), Broussard, DL, Sandborn, WJ, Rutgeerts, Paul, Colombel, JF, Rutgeerts, P, Broussard, Delma, L., Reinisch, Walter, Tang, KL, van Der Woude, Janneke, C., Diamond, Robert,, Kornbluth, A, Tang, K.L. (Kezhen ), Kornbluth, A. (Asher), Lichtiger, S. (Simon), Diamond, RH, Mantzaris, Gerassimos, J., Rachmilewitz, Daniel, Broussard, Delma,, Tang, Kezhen, L., D'Haens, G. (Geert), Lichtiger, Simon, Kornbluth, Asher, Reinisch, W, Rachmilewitz, D. (Daniel), d'Haens, Geert, Diamond, Robert, H., Broussard, D.L. (Delma ), Mantzaris, G.J. (Gerassimos ), Rutgeerts, P. (Paul), Rachmilewitz, D, Colombel, Jean Frédéric, Sandborn, William, J., Woude, C.J. (Janneke) van der, Reinisch, W. (Walter), van der Woude, C.J., Colombel, J.F. (Jean Frédéric), van Der Woude, Janneke,, Lichtiger, S, D'Haens, G, Mantzaris, Gerassimos,, Tang, Kezhen,, Mantzaris, GJ, Diamond, R.H. (Robert), Sandborn, William,   +44 more
core   +1 more source

Preparation and characterization of azathioprine microspheres for colon specific delivery

, 2019
The objective of the present study is to develop colon targeted drug delivery system using dextrin (polysaccharide) as a carrier for Azathioprine.  Microspheres containing azathioprine, dextrin and various excipients were prepared by solvent ...
Kori, Mohan Lal, Gonekar, Rinku
core   +1 more source

Upper and small bowel Crohn's disease in Brazilian children: Phenotypic characteristic and surgical risk

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Upper and small bowel Crohn's disease (U‐SBCD) represents a clinically aggressive phenotype with high complication rates yet remains diagnostically challenging. In low‐ and middle‐income countries (LMICs), limited inflammatory bowel disease (IBD) awareness contributes to diagnostic delays, but their impact on U‐SBCD outcomes remains
Jane Oba, Carlos Walter Sobrado, Elizete Aparecida Lomazi, Mariana Deboni, Michela Cynthia da Rocha Marmo, Vanessa Adriana Scheeffer, Silvio da Rocha Carvalho, Adérson Omar Mourão Cintra Damião, Matheus Freitas Cardoso de Azevedo, Carlos Frederico Sparapan Marques, Eytan Wine, Artur Figueiredo Delgado, Clovis Artur Almeida da Silva Full   +12 more
wiley   +1 more source