Results 121 to 130 of about 66,254 (246)

Long-Term Follow-up of Azathioprine-Induced Portosinusoidal Vascular Disease in a Patient With Crohn's Disease. [PDF]

open access: yesACG Case Rep J
Azizi F   +6 more
europepmc   +1 more source

Revisiting Ferritin‐IgG Score to Predict Complete Biochemical Response in Autoimmune Hepatitis

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
The ferritin‐IgG score failed external validation in a large Spanish multicentre cohort. However, baseline IgG ≥ 1.89×ULN independently predicted both complete biochemical response and biochemical response (defined as transaminase normalization), identifying patients less likely to achieve timely remission with standard therapy.
Álvaro Díaz‐González   +20 more
wiley   +1 more source

Corticosteroid Exposure in Autoimmune Hepatitis: Early Toxicity, Cumulative Burden and Associations With Long‐Term Patient‐Reported Outcomes

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In a patient‐reported cohort of 565 adults with autoimmune hepatitis, 96.6% reported corticosteroid‐related side effects within 6 months and long‐term toxicity increased with cumulative exposure. The findings support earlier tapering, toxicity monitoring, lower induction dosing when appropriate and selective budesonide use in carefully chosen non ...
Elizabeth Gentry   +4 more
wiley   +1 more source

Pulmonary hypertension secondary to IgG4-related disease: a case report and literature review. [PDF]

open access: yesOxf Med Case Reports
Alkhanafsa M   +5 more
europepmc   +1 more source

Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes   +7 more
wiley   +1 more source

Primary Cutaneous Gamma‐Delta T‐Cell Lymphoma Complicating Long‐Standing Immunosuppressed Dermatomyositis

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Primary cutaneous gamma‐delta T‐cell lymphoma (PCGD‐TCL) is a rare cytotoxic lymphoma with key oncogenic drivers in the JAK/STAT pathway. Also primarily involving the subcutaneous adipose tissue, subcutaneous panniculitis‐like T‐cell lymphoma (SPTCL) is more frequently encountered in scenarios of autoimmune disorders.
Bennett Christie‐Nguyen   +6 more
wiley   +1 more source

Aberrant Expression of Multiple T‐Cell Markers in Primary Cutaneous Follicle Center Lymphoma: A Rare Case Report

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Aberrant expression of T‐cell markers in B‐cell lymphomas is rare and can pose diagnostic challenges. We report a case of a 65‐year‐old man presenting with newly developed scalp nodules. Histopathology revealed nodular lymphoid infiltrates composed of large centrocytes and centroblasts.
V. Pfefferle   +4 more
wiley   +1 more source

Cyclophosphamide is associated with long‐term treatment‐free remission in patients with pemphigus

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objective Pemphigus treatment has seen significant advancements, yet long‐term remission remains a challenge. Comparative data on the long‐term effectiveness of available therapies are limited. We compared 10‐year relapse rates in pemphigus patients treated with azathioprine or cyclophosphamide plus high‐dose IV corticosteroids ...
Bettina Santler   +5 more
wiley   +1 more source

Effectiveness of Sulfasalazine Therapy Following Mesalazine Treatment Failure in Children with Ulcerative Colitis. [PDF]

open access: yesPediatr Gastroenterol Hepatol Nutr
Ruška P   +5 more
europepmc   +1 more source

A single‐center prospective observational study evaluating the efficacy and safety of tirbanibulin 1% in actinic keratoses in immunosuppressed patients: the ESTIMATE study

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Actinic keratoses (AKs) are common precursors to squamous cell carcinoma and pose a heightened risk in immunosuppressed patients, such as organ transplant recipients (OTRs). Patients and methods This prospective, monocentric, single‐arm observational study investigated the safety and efficacy of topical tirbanibulin 1% ointment in ...
Elisa Zavattaro   +4 more
wiley   +1 more source

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