Results 31 to 40 of about 133,046 (390)

Combination therapy with infliximab and azathioprine is superior to monotherapy with either agent in ulcerative colitis.

Gastroenterology, 2014
BACKGROUND & AIMS The comparative efficacy and safety of infliximab and azathioprine therapy alone or in combination for ulcerative colitis (UC) have not been evaluated previously.
R. Panaccione, Subrata Ghosh, S. Middleton, J. Marquez, B. Scott, Laurence Flint, H. van Hoogstraten, Annie C Chen, Hanzhe Zheng, S. Danese, P. Rutgeerts   +10 more
semanticscholar   +1 more source

Azathioprine Hypersensitivity Syndrome: Two Cases of Febrile Neutrophilic Dermatosis Induced by Azathioprine

Case Reports in Dermatology, 2017
Background: Azathioprine is an immunosuppressive agent used in the treatment of immune-mediated diseases. Azathioprine hypersensitivity syndrome is a rare adverse reaction occurring a few days to weeks after the administration of azathioprine.
Majed Aleissa, Perrine Nicol, Marion Godeau, Emilie Tournier, Frederic de Bellissen, Marie-Angèle Robic, Cristina Bulai Livideanu, Juliette Mazereeuw-Hautier, Carle Paul   +8 more
doaj   +1 more source

Prednisone, azathioprine, and N-acetylcysteine for pulmonary fibrosis.

New England Journal of Medicine, 2012
BACKGROUND A combination of prednisone, azathioprine, and N-acetylcysteine (NAC) has been widely used as a treatment for idiopathic pulmonary fibrosis. The safety and efficacy of this three-drug regimen is unknown.
G. Raghu, K. Anstrom, T. King, J. Lasky, F. Martinez   +4 more
semanticscholar   +1 more source

Liver dysfunction in patients with IBD under immunosuppressive treatment: do we need to fear? [PDF]

, 2010
International ...
Beaugerie, Laurent, Gerbes, Alexander L.
core   +3 more sources

Rituximab versus azathioprine for maintenance in ANCA-associated vasculitis.

New England Journal of Medicine, 2014
BACKGROUND The combination of cyclophosphamide and glucocorticoids leads to remission in most patients with antineutrophil cytoplasm antibody (ANCA)-associated vasculitides.
L. Guillevin, C. Pagnoux, A. Karras, C. Khouatra, O. Aumaître, P. Cohen, F. Maurier, O. Decaux, J. Ninet, P. Gobert, T. Quéméneur, C. Blanchard-Delaunay, P. Godmer, X. Puéchal, P. Carron, P. Hatron, N. Limal, M. Hamidou, M. Ducret, E. Daugas, T. Papo, B. Bonnotte, A. Mahr, P. Ravaud, L. Mouthon   +24 more
semanticscholar   +1 more source

Azathioprine favourably influences the course of malaria

Malaria Journal, 2009
Background Azathioprine triggers suicidal erythrocyte death or eryptosis, characterized by cell shrinkage and exposure of phosphatidylserine at the erythrocyte surface. Eryptosis may accelerate the clearance of Plasmodium-infected erythrocytes.
Huber Stephan M, Föller Michael, Geiger Corinna, Koka Saisudha, Bobbala Diwakar, Lang Florian   +5 more
doaj   +1 more source

Effects of oral administration of 5 immunosuppressive agents on activated T‐cell cytokine expression in healthy dogs

Journal of Veterinary Internal Medicine, 2020
Background Dogs are often adminstered >1 immunosuppressive medication when treating immune‐mediated diseases, and determining whether these different medications affect IL‐2 expression would be useful when performing pharmacodynamic monitoring during ...
Todd M. Archer, Charlee Mulligan, Lakshmi Narayanan, Caitlin Riggs, Claire Fellman, John M. Thomason, Robert W. Wills, Dawn M. Boothe, Crisanta Cruz‐Espindola, Roy Harmon, Andrew J. Mackin   +10 more
doaj   +1 more source

Azathioprine shock [PDF]

Postgraduate Medical Journal, 1986
Summary Azathioprine has been used as an immunosuppressant for over 20 years in cancer chemotherapy, organ transplantation and diseases with confirmed or suspected immune mechanisms. A hypersensitivity reaction manifesting as fever, rash, myalgia and a neutrophil leucocytosis occurring about 2 weeks after exposure is well documented and ...
openaire   +2 more sources

Utility of Maternal 6-Thioguanine Nucleotide Levels in Predicting Neonatal Pancytopenia

American Journal of Perinatology Reports, 2013
An infant with pancytopenia was born to a mother who used the common immunosuppressant azathioprine (AZA). Maternal and neonatal blood levels of 6-thioguanine nucleotides (6TGN; metabolite of AZA) were 1890 and 1480 pmol/8 × 108 red blood cells ...
Hidehiko Maruyama, Katsuhiko Tada, Takuzo Fujiwara, Kosuke Ota, Misao Kageyama   +4 more
doaj   +1 more source

Immunoglobulin G4-Hepatopathy with Acute Hepatitis-Like Onset and Marked Centrilobular Necrosis: Clinicopathologically Unique Pattern of Hepatic Injury Related to Immunoglobulin G4-Related Disease

Case Reports in Gastroenterology, 2021
A 69-year-old man presented with jaundice and appetite loss. Blood analyses showed elevated aminotransferase levels, hyperbilirubinemia, positivity for antinuclear antibody, elevated immunoglobulin (Ig) G4 levels, and negativity for hepatitis virus ...
Kaori Mukai, Tsutomu Nishida, Shiro Adachi, Kengo Matsumoto, Naoto Osugi, Aya Sugimoto, Dai Nakamatsu, Masashi Yamamoto, Koji Fukui, Hiromi Tamura, Masami Inada   +10 more
doaj   +1 more source