Results 51 to 60 of about 133,046 (390)

Influence of probiotics and deoxycholate on azathioprine transport in the PAMPA model: insights into pharmacomicrobiomics and interindividual variability in drug response

Frontiers in Pharmacology
IntroductionInterindividual variability in drug response presents a major clinical challenge, necessitating a deeper understanding of contributing factors.
Maja Đanić, Nebojša Pavlović, Natalija Dedić, Dragana Zaklan, Slavica Lazarević, Bojan Stanimirov, Momir Mikov   +6 more
doaj   +1 more source

Azathioprine and Risk of Skin Cancer in Organ Transplant Recipients: Systematic Review and Meta‐Analysis

American Journal of Transplantation, 2016
Azathioprine, a purine antimetabolite immunosuppressant, photosensitizes the skin and causes the production of mutagenic reactive oxygen species. It is postulated to increase the risk of squamous cell carcinoma (SCC) and other skin cancers in organ ...
Z. Jiyad, Z. Jiyad, C. M. Olsen, C. M. Olsen, M. Burke, N. Isbel, Adèle C. Green, Adèle C. Green   +7 more
semanticscholar   +1 more source

Treatment of Psoriasis with Azathioprine [PDF]

BMJ, 1974
Azathioprine treatment benefited 19 (66%) out of 29 patients suffering from severe psoriasis. Haematological complications were not troublesome and results of biochemical liver function tests remained normal. Minimal cholestasis was seen in two cases and portal fibrosis of a reversible degree in eight.
Dowling D. Munro, Julian Verbov, Anthony du Vivier   +2 more
openaire   +3 more sources

Acute-onset Alopecia in a Child: A Surrogate Marker of Azathioprine-induced Myelotoxicity

Indian Journal of Paediatric Dermatology, 2023
Azathioprine (AZA) is a widely used immunosuppressive which when not monitored cautiously can lead to life-threatening complications like myelotoxicity. In resource-limited countries, acute hair loss starting as early as 2 weeks after drug initiation can
Vibhu Mendiratta, Akanksha Agarwal, Smita Singh   +2 more
doaj   +1 more source

Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis.

Cochrane Database of Systematic Reviews, 2016
BACKGROUND Maintenance of remission is a major issue in inflammatory bowel disease. In ulcerative colitis, the evidence for the effectiveness of azathioprine and 6-mercaptopurine for the maintenance of remission is still controversial.
A. Timmer, P. Patton, N. Chande, J. McDonald, J. Macdonald   +4 more
semanticscholar   +1 more source

Brain Characteristics in Patients With Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disorder by 7.0 Tesla MRI

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) can radiographically mimic multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD). The disease hallmarks cortical lesion, central vein sign (CVS) and paramagnetic rim lesions identified in MS have not yet been comprehensively investigated in ...
Lei Su, Joseph Kuchling, Chenyang Gao, Thoralf Niendorf, Carsten Finke, Zhe Zhang, Ai Guo, Jing Jing, De‐Cai Tian, Yu‐Jing Li, Mengting Zhang, Xiaoyu Shi, Xinyao Liu, Huabing Wang, Yaou Liu, Claudia Chien, Michael Levy, Yunyun Duan, Friedemann Paul, Fu‐Dong Shi   +19 more
wiley   +1 more source

Effect of conversion from azathioprine to mycophenolate mofetil on renal function in stable kidney transplant recipients

Turkish Journal of Internal Medicine, 2019
Aim: This study investigated the effect of mycophenolate mofetil (MPA) treatment instead of azathioprine (AZA) on renal function after kidney transplantation.
Mehmet Usta, Yavuz Ayar, Alparslan Ersoy
doaj   +1 more source

A Real-World Experience of Azathioprine Versus First-Line Disease-Modifying Therapy in Relapsing-Remitting Multiple Sclerosis—A Prospective Cohort Study

Brain Sciences, 2023
Azathioprine (AZA) has demonstrated efficacy in multiple randomized control trials (RCTs) for Relapsing-Remitting Multiple Sclerosis (RRMS). However, we still need comparative real-world data with other first-line disease-modifying therapies (DMTs).
Arpit Agrawal, M. V. Padma Srivastava, Rohit Bhatia, Vinay Goyal, Mamta Bhushan Singh, Venugopalan Y. Vishnu, Anuj Prabhakar   +6 more
doaj   +1 more source

Second cadaver kidney transplants: Improved graft survival in secondary kidney transplants using cyclosporin A [PDF]

, 1984
A total of 42 patients who failed prior renal transplantation underwent repeat cadaveric transplantation cyclosporin A and low dose immunosuppression. Patient survival at 1 year was 100 per cent.
Caine, Ferguson, Flechner, Gifford, Opelz, Starzl, Starzl, Sutherland   +7 more
core   +1 more source

Azathioprine or 6-mercaptopurine for induction of remission in Crohn's disease.

Cochrane Database of Systematic Reviews, 2016
BACKGROUND The results from controlled clinical trials investigating the efficacy of azathioprine and 6-mercaptopurine for the treatment of active Crohn's disease have been conflicting and controversial.
N. Chande, C. Townsend, C. Parker, J. Macdonald   +3 more
semanticscholar   +1 more source