Results 61 to 70 of about 71,298 (290)

Experts opinion on the practical use of azathioprine and 6-mercaptopurine in inflammatory bowel disease [PDF]

, 2016
The relevance of azathioprine and 6-mercaptopurine therapy in inflammatory bowel disease, Crohn's disease, and ulcerative colitis, has been challenged in recent publications.
Kessler-Brondolo, Vera, Seibold, F., Rogler, Gerhard, Juillerat, P., Mottet, Christian, Froehlich, Florian, Rogler, G., Seibold, Frank, Schoepfer, A.M., Froehlich, F., Michetti, P., Cosnes, Jacques, Vavricka, S.R., Juillerat, Pascal, Michetti, Pierre, Cosnes, J., Vavricka, Stephan R, Schoepfer, Alain M, Mottet, C., Kessler-Brondolo, V.   +19 more
core   +1 more source

Anti‐CD19 CAR T Cells in Autoimmune Encephalitis: Inflammation Controlled, Neurodegeneration Unchecked?

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos, Marwa Al‐Dubai, Denise Walther, Dominic Borie, Jan D. Lünemann, Marc Pawlitzki, Sven G. Meuth, Solveig Henneicke, Stefan Vielhaber, Stefanie Schreiber   +9 more
wiley   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Proactive pharmacogenomics in azathioprine-treated pediatric inflammatory bowel disease at a Chinese tertiary hospital

Frontiers in Pharmacology
BackgroundDespite the emergence of numerous innovative targeted therapies for the management of pediatric inflammatory bowel disease (IBD), azathioprine continues to be a pivotal first-line therapeutic agent.
Cai-Yun Long, Ying Huang
doaj   +1 more source

Hypersensitivity Reaction to Azathioprine

, 1998
Adverse drug reactions can vary from a simple rash to anaphylactic shock. While certain medications including the penicillins are well known to cause such reactions, other drugs are not as commonly recognized. Azathioprine hypersensitivity reactions tend
RYLAND P. BYRD, Roy, Thomas M., CHERYL L. FIELDS, Byrd, Ryland P., Robinson, Jeffrey W., JEFFREY W. ROBINSON, MIGUEL A. OSSORIO, THOMAS M. ROY, Ossorio, Miguel A., Fields, Cheryl L.   +9 more
core   +1 more source

Efficacy of Inebilizumab in N‐MOmentum Trial Participants With or Without Prior Immunosuppressants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This post hoc analysis examined the impact of prior immunosuppressants on the long‐term efficacy and safety of inebilizumab, a cluster of differentiation 19+ B‐cell–depleting monoclonal antibody, in participants with aquaporin‐4–seropositive neuromyelitis optica spectrum disorder from the N‐MOmentum trial (NTC02200770).
Bruce A. C. Cree, Beatrice Suero, Sarah Walsh, Romain Marignier, John W. Lindsey, Ho Jin Kim, Dewei She, Daniel Cimbora, Dustin Cavida, Friedemann Paul   +9 more
wiley   +1 more source

Azathioprine-lnduced Fever in Sarcoidosis

, 2011
Objective: To report a case of drug-induced fever associated with azathioprine treatment in a patient with sarcoidosis. Case Summary: A 52-year-old man with pulmonary sarcoidosis presented to the emergency department with a 1 -day history of fever ...
Carlos Rojas, Sarah McBane
core   +1 more source

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah, Sangmee S. Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

Phagocytosis and Epithelial Cell Invasion by Crohn’s Disease-Associated Adherent-Invasive Escherichia coli Are Inhibited by the Anti-inflammatory Drug 6-Mercaptopurine

Frontiers in Microbiology, 2018
Adherent-invasive Escherichia coli (AIEC) strains are overrepresented in the dysbiotic microbiota of Crohn’s disease (CD) patients, and contribute to the onset of the chronic inflammation typical of the disease.
Federica Migliore, Raffaella Macchi, Paolo Landini, Moira Paroni   +3 more
doaj   +1 more source

Neuropsychiatric Outcome of Children Born to Women With Systemic Lupus Erythematosus and Exposed in Utero to Azathioprine: A Case-Control Study

Frontiers in Pharmacology, 2020
Objective: The long-term outcome of children born to SLE mothers still represents a controversial topic in literature, with some studies reporting a possible increased prevalence of different neurologic and psychiatric diseases (NPD), including ...
Maria-Grazia Lazzaroni, Maria-Grazia Lazzaroni, Laura Andreoli, Laura Andreoli, Francesca Crisafulli, Francesca Crisafulli, Francesco Tamborini, Irene Debeni, Valentina Binda, Cecilia Nalli, Jessica Galli, Jessica Galli, Elisa Fazzi, Elisa Fazzi, Gabriella Moroni, Franco Franceschini, Franco Franceschini, Angela Tincani, Angela Tincani, Angela Tincani   +19 more
doaj   +1 more source