Results 1 to 10 of about 8,726 (224)

Preparation and Evaluation of Azelaic Acid Topical Microemulsion Formulation: In Vitro and In Vivo Study [PDF]

Pharmaceutics, 2021
The aim of this study was to design oil in water (O/W) microemulsion formulations for the topical administration of azelaic acid. The permeability of azelaic acid through rat skin and the anti-inflammatory activities of the formulations were conducted to
Wan-Hsuan Hung, Ping-Kang Chen, Chih-Wun Fang, Ying-Chi Lin, Pao-Chu Wu   +4 more
doaj   +2 more sources

Effect of Azelaic Acid on Psoriasis Progression Investigated Based on Phosphatidylinositol 3-Kinase (PI3K)/Protein Kinase B (AKT) Signaling Pathway [PDF]

Clinical, Cosmetic and Investigational Dermatology, 2022
Licui Li,1,2 Huixiu Lu,1,3 Yanli Zhang,4 Qian Li,4 Shaomin Shi,4 Yaling Liu1,4 1Department of Dermatology and Venereology, Hebei Medical University, Shijiazhuang, People’s Republic of China; 2Department of Dermatology, Shijiazhuang Gaocheng People’s ...
Li L, Lu H, Zhang Y, Li Q, Shi S, Liu Y
doaj   +2 more sources

The efficacy and safety of minocycline, metronidazole, ivermectin, and azelaic acid in moderate-to-severe papulopustular rosacea: A systematic review and network meta-analysisCapsule Summary [PDF]

JAAD International
Background: There are multiple topical agents for papulopustular rosacea (PPR), but the most effective for the management of moderate-to-severe PPR remains unknown.
Esraa A. Shaheen, MD, Yara E. Aljefri, MD, Abdullah A. Ghaddaf, MD, Khalid M. Alshareef, MD, Abeer K. Alhindi, MD, Narin F. Alanazi, MD, Anwar R. Alrashidi, MD, Abdulhadi Jfri, MD, MSc   +7 more
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New insights into the anti-inflammatory and anti-melanoma mechanisms of action of azelaic acid and other Fusarium solani metabolites via in vitro and in silico studies [PDF]

Scientific Reports
Metabolites exploration of the ethyl acetate extract of Fusarium solani culture broth that was isolated from Euphorbia tirucalli root afforded five compounds; 4-hydroxybenzaldehyde (1), 4-hydroxybenzoic acid (2), tyrosol (3), azelaic acid (4), malic acid
Mona Ismail, Marwa H. A. Hassan, Enas I. A. Mohamed, Ahmed F. Azmy, Abeer Moawad, Rabab Mohammed, Mohamed A. Zaki   +6 more
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Formulation, in silico, in vitro characterization, cytotoxicity and cellular uptake of cyclodextrin complexes and ion pairing/salt formation with functional excipients (azelaic acid, tartaric acid, and arginine) with raloxifene [PDF]

International Journal of Pharmaceutics: X
With advancements in drug repurposing, the search for effective and less harmful anticancer agents remains a critical endeavor. Raloxifene, although not a typical anticancer drug, holds promise in this context.
Hamdy Abdelkader, Adel Al-Fatease, Ali H. Alamri, Mai E. Shoman, Hend Mohamed Abdel-Bar, Zeinab Fathalla   +5 more
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Ozonated Sunflower Oil Embedded within Spray-Dried Chitosan Microspheres Cross-Linked with Azelaic Acid as a Multicomponent Solid Form for Broad-Spectrum and Long-Lasting Antimicrobial Activity [PDF]

Pharmaceutics
Multicomponent solid forms for the combined delivery of antimicrobials can improve formulation performance, especially for poorly soluble drugs, by enabling the modified release of the active ingredients to better meet therapeutic needs.
Roberto Spogli, Caterina Faffa, Valeria Ambrogi, Vincenzo D’Alessandro, Gabriele Pastori   +4 more
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Development and Evaluation of Azelaic Acid-Loaded Microemulsion for Transfollicular Drug Delivery Through Guinea Pig Skin: A Mechanistic Study [PDF]

Advanced Pharmaceutical Bulletin, 2020
Purpose: Azelaic acid is a natural keratolytic, comedolytic, and antibacterial drug that is used to treat acne. The topical application of azelaic acid is associated with problems such as irritation and low permeability.
Anayatollah Salimi, Behzad Sharif Makhmal Zadeh, Salar Godazgari, Abbas Rahdar   +3 more
doaj   +1 more source

A COMPARISON OF EFFICACY OF INTRADERMAL TRANEXAMIC ACID WITH TOPICAL 20% AZELAIC ACID IN THE TREATMENT OF MELASMA

Pakistan Armed Forces Medical Journal, 2021
Objective: To compare the efficacy of Intradermal Tranexamic acid and topical 20% Azelaic acid cream in the treatment of melasma. Study Design: Comparative prospective study.
Sayyida Komal, Asher Ahmed Mashhood, Muhammad Farooq, Nida Qayyum   +3 more
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Azelaic acid stimulates catalase activation and promotes hair growth through upregulation of Gli1 and Gli2 mRNA and Shh protein [PDF]

Avicenna Journal of Phytomedicine, 2020
Objective: Although azelaic acid is effective for treatment of acne and rosacea, the biological activity of azelaic acid and the effect of its combination therapy with minoxidil were not elucidated with regard to hair growth.
Elham Amirfakhryan, Nowruz Najafzadeh, Behzad Davarnia, Farhad Jeddi   +3 more
doaj   +1 more source

Determination of azelaic acid and potassium azeloycinate diglycinate in cosmetics by HPLC

Shanghai yufang yixue, 2022
ObjectiveAn HPLC method was established for the determination of azelaic acid and potassium azeloycinate diglycinate in cosmetics.MethodsThe samples were extracted with 60 mmol·L-1 sodium hydroxide water solution-methyl alcohol.
XU Yong, HAN Jing, YU Ling, HUI Taicheng, HUANG Jun, PENG Xingsheng, ZHENG Rong   +6 more
doaj   +1 more source