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Azelaic acid--biochemistry and metabolism.
Acta dermato-venereologica. Supplementum, 1989Medium chain length dicarboxylic acids (DA) from C8 to C13 are competitive inhibitors of tyrosinase in vitro. The introduction of electron acceptor groups or electron donor groups into the 2 and/or the 8 position of the molecule enhances or reduces respectively the inhibitory effects of DA.
Passi, S +4 more
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Pharmacology and toxicology of azelaic acid.
Acta dermato-venereologica. Supplementum, 1989The results of general pharmacological studies on metabolism, smooth muscles, renal function, cardiovascular and neurotropic effects do not contra-indicate the specific surface use of azelaic acid. From specific pharmacologic studies it is assumed that azelaic acid exerts its therapeutic effect in acne by an antimicrobial, probably bacteriostatic ...
M, Töpert, P, Rach, F, Siegmund
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The versatility of azelaic acid in dermatology
Journal of Dermatological Treatment, 2022Tamara Searle +2 more
exaly
Azelaic acid therapy for acne.
American family physician, 1997Azelaic acid is another option for the topical treatment of mild to moderate inflammatory acne vulgaris. It offers effectiveness similar to that of other agents without the systemic side effects of oral antibiotics or the allergic sensitization of topical benzoyl peroxide and with less irritation than tretinoin.
P S, Mackrides, A F, Shaughnessy
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The evolution of azelaic acid.
Cutis, 2006Azelaic acid (AzA) is a naturally occurring dicarboxylic acid that has a long and complex history in the treatment of skin disorders. We summarize research on AzA from the past 25 years and follow its progress from a treatment of hyperpigmentation to a therapy for acne vulgaris and inflammatory (papulopustular) rosacea.
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