Results 141 to 150 of about 2,792 (191)

Catalytic Transformations of Aza-Cyclobutenes, Fused Cyclobutenes, and Cyclobutenones. [PDF]

Chem Rec
Aziz A, Yang Z.
europepmc   +1 more source

Minoxidil Sulfate Regulates JAK/STAT Signalling and Mitochondrial Function in Alopecia Areata. [PDF]

Exp Dermatol
Shin JM, Go B, Jung KE, Kim CD, Seo YJ, Lee Y.   +5 more
europepmc   +1 more source

Formal Markovnikov Hydroazolation of Alkenes via Reductive Activation of Alkylthianthrenium Salts. [PDF]

J Am Chem Soc
Matthews AD, Lorenz JR, Wickens ZK.
europepmc   +1 more source

Pharmaceutical Research - Academic Collaborations: An Insider's Perspective. [PDF]

ACS Med Chem Lett
Djuric SW.
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Ring opening of photogenerated azetidinols as a strategy for the synthesis of aminodioxolanes. [PDF]

Beilstein J Org Chem
Maag H, Lemcke DJ, Wahl JM.
europepmc   +1 more source

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Divergent Functionalizations of Azetidines and Unsaturated Azetidines

Asian Journal of Organic Chemistry, 2019
AbstractAzetidines are unusual heterocyclic motifs that comprise key components of biologically active molecules and provide desirable structural properties for drug discovery. While a variety of methods have been designed for the synthesis of azetidines, screening and optimization studies often require systematic and versatile strategies for varying ...
Laura L Anderson, Tyler W Reidl
exaly   +2 more sources

Selective Reductive Elimination at Alkyl Palladium(IV) by Dissociative Ligand Ionization: Catalytic C(sp3)−H Amination to Azetidines [PDF]

Angewandte Chemie - International Edition, 2018
A palladium(II)-catalyzed γ-C-H amination of cyclic alkyl amines to deliver highly substituted azetidines is reported. The use of a benziodoxole tosylate oxidant in combination with AgOAc was found to be crucial for controlling a selective reductive ...
Manuel Nappi, Matthew J. Gaunt, Chuan He
exaly   +3 more sources

Azetidines of pharmacological interest

Archiv der Pharmazie, 2021
AbstractAzetidines are almost unexplored among nitrogen‐containing saturated heterocycles due to difficulties associated with their synthesis. However, over the past few years, attempts have been made by scientists to advance their synthetic feasibility.
Deepa R. Parmar, Jigar Y. Soni, Ramakrishna Guduru, Rahul H. Rayani, Rakesh V. Kusurkar, Anand G. Vala   +5 more
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Synthesis of Azetidines

Journal of Pharmaceutical Sciences, 1971
The synthesis of 3-amino-2-phenylazetidine and the p-chloro analog is reported. The reduction of azetidinones with diborane was investigated and found successful with N-unsubstituted systems. 3-Amino-2-phenylazetidine was found active in vitro against monoamine oxidase.
J N, Wells, O R, Tarwater
openaire   +2 more sources

Facile Synthesis of Azetidine Nitrones and Diastereoselective Conversion into Densely Substituted Azetidines

Angewandte Chemie - International Edition, 2017
AbstractAn electrocyclization route to azetidine nitrones from N‐alkenylnitrones was discovered that provides facile access to these unsaturated strained heterocycles. Reactivity studies showed that these compounds undergo a variety of reduction, cycloaddition, and nucleophilic addition reactions to form highly substituted azetidines with excellent ...
Donald J. Wink, Laura L Anderson, Jongwoo Son   +2 more
exaly   +5 more sources