Results 71 to 80 of about 2,385 (114)

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, Volume 19, Issue 11, Page 3409-3426, November 2025.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

B lymphocytes and tertiary lymphoid structures have a prognostic impact on penile squamous cell carcinoma

The Journal of Pathology: Clinical Research, Volume 11, Issue 6, November 2025.
Abstract Several prognostic markers, including tumor‐infiltrating lymphocytes, which have been recently identified in penile squamous cell carcinoma (pSCC), have focused mostly on T cells. The prognostic role of B cells and tertiary lymphoid structures (TLSs) has not yet been sufficiently described. We examined whole tissue sections histopathologically
Nicolette Zavillová, Petr Waldauf, Michaela Kendall Bártů, David Čapka, Jan Hojný, Zuzana Prouzová, Radoslav Matěj, Roman Zachoval, Jan Hrudka   +8 more
wiley   +1 more source

Manejo e controle de azevém resistente ao glifosato. [PDF]

, 2017
Fatores responsáveis por aplicações ineficientes de herbicidas. Herbicidas graminicidas e não-seletivos que controlam azevém resistente e sensível ao glifosato.
VARGAS, L., KARAM, D., GAZZIERO, D. L. P.   +2 more
core   +3 more sources

Philadelphia chromosome‐positive acute lymphoblastic leukaemia in children and adolescents: A changing treatment landscape and a methodological challenge

British Journal of Haematology, Volume 208, Issue 3, Page 1127-1132, March 2026.
Adriana Balduzzi, Maria Grazia Valsecchi, Thai Hoa Tran, Jan Zuna, Veronica Leoni, Gunnar Cario, Grazia Fazio, Virginie Gandemer, Sarah K. Tasian, Inge M. van der Sluis, Nicolò Peccatori, Rosanna Parasole, Stefania Monterisi, Mignon L. Loh, Meenakshi Devidas, Stephen P. Hunger, John A. Kairalla, Paola De Lorenzo, Lewis B. Silverman, Andrea Biondi   +19 more
wiley   +1 more source

Treatment Cessation in Chronic Myeloid Leukemia: Evidence and Uncertainties

Hematological Oncology, Volume 43, Issue 6, November 2025.
ABSTRACT Testing to discontinue imatinib already started some years after the advent of this new CML therapy. Since that time, despite many trials and studies in this field, there are still significant gaps, and many fundamental questions remain unanswered. Probably the most intriguing is the persistence of minimal residual disease, which does not lead
Jiří Mayer
wiley   +1 more source

Pigmentos fotossintéticos em azevém suscetível e resistente ao herbicida glyphosate [PDF]

, 2014
O objetivo deste trabalho foi quantificar o teor de pigmentos fotossintéticos em biótipos de azevém (Lolium multiflorum) suscetíveis e resistentes ao glyphosate, por dois diferentes métodos, bem como, estabelecer uma correlação entre o índice de ...
Isabel Bellinaso Pagliarini, Carlos Alberto Gonsiorkiewicz Rigon, Fabiane Pinto Lamego, Tiago Edu Kaspary, Sabrina Tolotti Peruzzo   +4 more
core   +1 more source

Electrical Remodeling of Pressure Overloaded Rat Heart Is Attenuated if Imposed During Proliferative Cardiac Growth

Acta Physiologica, Volume 241, Issue 11, November 2025.
ABSTRACT Aim Left ventricular pressure overload (LVPO) in adults is associated with adverse electrical remodeling, characterized by reduced conduction velocity (CV). However, the progression of LVPO differs when imposed during the proliferative phase of cardiac development.
Eva Nekvindova, Jaroslav Hrdlicka, Almos Boros, Michaela Slegrova, Alena Kvasilova, Vojtech Skop, Jan Halberstat, Kristyna Holzerova, Jan Neckar, David Sedmera, Veronika Olejnickova   +10 more
wiley   +1 more source

Morfogênese e estrutura de azevém anual submetido a três intensidades de pastejo - doi: 10.4025/actascianimsci.v32i4.8657

Acta Scientiarum: Animal Sciences, 2010
Estudaram-se características morfogênicas e estruturais de azevém (Lolium multiflorum Lam.) sob intensidades de pastejo. O delineamento experimental foi inteiramente casualizado, com quatro repetições (transectas) e três tratamentos constituídos por ...
Anna Carolina Cerato Confortin, Fernando Luiz Ferreira de Quadros, Marta Gomes da Rocha, Daniele Gindri de Camargo, Carine Lisete Glienke, Bruno Castro Kuinchtner   +5 more
doaj   +1 more source

OMIP‐117: 40‐Parameter/37‐Color Spectral Cytometry Panel for Robust Immunoprofiling of Human Lymphoid Subsets in Cancer Patients

Cytometry Part A, Volume 107, Issue 10, Page 641-648, October 2025.
ABSTRACT The analysis of immune cell compartments in cancer patients is crucial to predict treatment efficacy and relapse. We introduce a robust 40‐parameter, 37‐channel spectral cytometry panel designed to profile human lymphoid subsets and CAR‐T cell expansion, with the capability to assess exhaustion status by profiling immune checkpoints and ...
Ondrej Venglar, Eva Radova, Lucie Broskevicova, Roman Hajek, Tomas Jelinek   +4 more
wiley   +1 more source

Produção de forragem de cultivares de aveia no planalto catarinense [PDF]

, 2015
TCC (graduação)- Universidade Federal de Santa Catarina. Campus Curitibanos. Agronomia.A aveia é uma gramínea de inverno amplamente utilizada na região sul, que possui grande diversidade de cultivares disponíveis no mercado.
Moraes, Renata Franciéli
core