Results 11 to 20 of about 1,216 (196)

A Novel Class of "Super-Strained" Spiro Heterocycles: Gateway to 1-Azaspiro[3.3]heptane Derivatives, and Biological Validation. [PDF]

Angew Chem Int Ed Engl
A new class of “super‐strained” spiro heterocycles—spirocyclic 1‐azabicyclo[1.1.0]butanes—was synthesized via insertion of cyclobutane‐, oxetane‐, and azetidine‐containing sulfonium reagents into substituted azirines. The stability of this new class of compounds was studied.
Natho P, Vicenti A, Colella M, Pasca F, Romanazzi G, Niso M, Abate C, Mesto E, Schingaro E, Luisi R.   +9 more
europepmc   +3 more sources

<i>Hj</i>-aggregates of quinoline-fused boron-dipyrromethene nanoparticles for near-infrared dualmodal photodynamic and photothermal therapy. [PDF]

Smart Mol
A novel quinoline‐fused cyclic pyrrole is synthesized via lithium diisopropylamide‐catalyzed [3 + 2] cyclization, enabling the construction of a symmetrical boron‐dipyrromethene photosensitizer that forms Hj‐aggregates upon nanoparticle encapsulation.
Zhang B, Du C, Yang Y, Xu D, Jiang XD, Liu HX, Qin G.   +6 more
europepmc   +2 more sources

A Chemical Framework for Engineering Extracellular Vesicles' Biointerface to Advance Precision Therapeutics. [PDF]

Adv Mater
Extracellular vesicles (EVs) are cell‐derived nanoparticles that mediate intercellular communication through their dynamic biointerfaces. Owing to their intrinsic biological functions, EVs have emerged as promising platforms for biomedical applications.
Pourtalebi Jahromi L, Geng F, Frenzke JN, Fuhrmann G.   +3 more
europepmc   +2 more sources

Synthesen und Reaktionen neuer Brückenkopf-Azirine [PDF]

, 2009
In der vorliegenden Arbeit wird die Darstellung einer Vielzahl neuer, hochreaktiver Brückenkopf-Azirine dokumentiert. Diese können ausschließlich photochemisch aus den entsprechenden, zum Teil ebenfalls unbekannten carbocyclischen Vinylaziden erzeugt ...
Penk, Enrico
core   +3 more sources

Structure, spectroscopic signatures, and formation of hydroxy-azirine: a potential interstellar prebiotic molecule [PDF]

, 2023
Producción CientíficaHydroxy-azirine (C2H3NO) is a -OH derivative of azirine (C2H3N), molecule that has been the subject of several unfruitful searches in space.
Barrientos Benito, María Carmen, Redondo Cristóbal, María del Pilar, Sanz Novo, Miguel, Largo Cabrerizo, Antonio   +3 more
core   +1 more source

Synthesis of α-Aminophosphonic Acid Derivatives Through the Addition of O- and S-Nucleophiles to 2H-Azirines and Their Antiproliferative Effect on A549 Human Lung Adenocarcinoma Cells

Molecules, 2020
This work reports a straightforward regioselective synthetic methodology to prepare α-aminophosphine oxides and phosphonates through the addition of oxygen and sulfur nucleophiles to the C–N double bond of 2H-azirine derivatives. Determined by the nature
Victor Carramiñana, Ana M. Ochoa de Retana, Francisco Palacios, Jesús M. de los Santos   +3 more
doaj   +1 more source

Photochemische Cycloaddition von 3-Phenyl-2H-azirinen mit Ketenen

CHIMIA, 1972
Irradiation of 2,2-dimethyl-3-phenyl- (1c) and 2,3-diphenyl-2H-azirine (1d) in benzene solution in the presence of ketene (5) yields 2,2-dimethyl-4-phenyl- (6) and 2,4-diphenyl-5-methylen-3-oxazoline (7), respectively. Similar cycloadducts (9a to d) are
H. Heimgartner, P. Gilgen, U. Schmid, H.-J. Hansen, H. Schmid, K. Pfoertner, K. Bernauer   +6 more
doaj   +1 more source

Access to highly substituted oxazoles by the reaction of α-azidochalcone with potassium thiocyanate

Beilstein Journal of Organic Chemistry, 2020
The reactivity of α-azidochalcones has been explored for the preparation of highly substituted oxazoles via a 2H-azirine intermediate. The azidochalcones, when treated with potassium thiocyanate in the presence of potassium persulfate, lead to 2,4,5 ...
Mysore Bhyrappa Harisha, Pandi Dhanalakshmi, Rajendran Suresh, Raju Ranjith Kumar, Shanmugam Muthusubramanian   +4 more
doaj   +1 more source

Copper(II)-Catalyzed (3+2) Cycloaddition of 2H-Azirines to Six-Membered Cyclic Enols as a Route to Pyrrolo[3,2-c]quinolone, Chromeno[3,4-b]pyrrole, and Naphtho[1,8-ef]indole Scaffolds

Molecules, 2022
A method for the [2+3] pyrroline annulation to the six-membered non-aromatic enols using 3-aryl-2H-azirines as annulation agents is developed in the current study.
Pavel A. Sakharov, Nikolai V. Rostovskii, Alexander F. Khlebnikov, Mikhail S. Novikov   +3 more
doaj   +1 more source

Electrochemically Induced Synthesis of Imidazoles from Vinyl Azides and Benzyl Amines

Molecules, 2022
An electrochemically induced synthesis of imidazoles from vinyl azides and benzyl amines was developed. A wide range of imidazoles were obtained, with yields of 30 to 64%.
Vera A. Vil’, Sergei S. Grishin, Alexander O. Terent’ev   +2 more
doaj   +1 more source