Results 41 to 50 of about 455 (164)

Push–Pull Ynamines and Push–Pull Ynamides: Synthesis, Structure, Reactivity, and Application

European Journal of Organic Chemistry, Volume 29, Issue 19, 22 May 2026.
Push–pull ynamines and push–pull ynamides, which carry an EWG and an amino or amido group as EDG, are highly interesting classes of EDG‐EWG alkynes that have been intensively studied due to their exceptional reactivity. In this review, the synthesis, structure, reactivity, and application of push–pull ynamines, push–pull ynecarbamates, push–pull ...
Hans‐Joachim Gais
wiley   +1 more source

Composite Single‐Reference and Explicitly Correlated Multireference Calculations on the Mechanism of Pyrrole Pyrolysis

Journal of Physical Organic Chemistry, Volume 39, Issue 4, April 2026.
New calculations have been applied to the pyrolysis of pyrrole under shock‐tube conditions and to the radical‐radical reaction between allyl and •CN at low temperature and pressure, using the same mechanistic scheme for both. ABSTRACT The pyrolysis of pyrrole has previously been studied in shock‐tube experiments and in jet‐stirred reactors. The results
Barry K. Carpenter
wiley   +1 more source

Synthesis of 2-Aminonicotinonitriles via Photodecarboxylation of Azirine-2-Carboxylic Acids

Molbank
2-Aminonicotinonitriles represent an important class of heterocycles with diverse biological activities. Herein, we report an unexpected photochemical transformation of azirine-2-carboxylic acids leading to the formation of 2-aminonicotinonitrile ...
Julia I. Pavlenko, Mikhail S. Novikov, Anastasiya V. Agafonova   +2 more
doaj   +1 more source

Recent Contributions of Organic Synthesis to Forensic Science

ChemPlusChem, Volume 91, Issue 2, February 2026.
Forensic science is a multidisciplinary field that plays a vital role in providing scientific evidence for criminal investigations. This review highlights advances and opportunities at the interface between organic synthesis and forensic science, with applications in drug identification, forensic toxicology, and latent fingerprint detection and ...
Gustavo dos Santos Martins, Mariana dos Santos Dupim, Rodrigo Garcia Agostinho, Fernanda Gadini Finelli   +3 more
wiley   +1 more source

2H-Pyrrole und Pyrrole aus 3-Phenyl-2H-azirinen

CHIMIA, 1976
Vinyl-phosphonium salts [2] and phenyl-vinyl-sulfone or divinylsulfone react with benzonitril-methylides a (which are photochemically generated from 3-phenyl-2H-azirines 1 and 2) to give, via the nonisolated intermediates of type b, 2H-pyrrole 4 and the
Ulrich Widmer, Nikolas Gakis, Bruno Arnet, Heinz Heimgartner, Hans Schmid   +4 more
doaj   +1 more source

Trapping an Aryl‐substituted Borete Intermediate in Catalyst‐free 1,5‐Diborocine Synthesis

European Journal of Inorganic Chemistry, Volume 29, Issue 4, February 1, 2026.
A transient aryl‐substituted borete was trapped as its adduct with 4‐(dimethylamino)pyridine (dmap) and fully characterised. While the dmap adduct is highly kinetically stable, the free borete could not be observed in the absence of dmap. Density‐functional calculations support a rapid dimerisation of the borete via (4 + 4) cycloaddition, yielding a 1 ...
Douglas Turnbull, Marc‐André Légaré
wiley   +1 more source

Development of a Copper‐Free Click Reaction for Asymmetric Rh Diene Catalysis Under Confinement

Advanced Synthesis &Catalysis, Volume 368, Issue 1, January 2026.
A copper‐free amino–yne click reaction enables the selective functionalization of chiral diene ligands with both soluble and immobilized amines. Substituent‐controlled stereoselectivity affords (E)‐ and (Z)‐enaminone ligands, which are converted into Rh complexes for asymmetric catalysis under homogeneous and heterogeneous conditions.
Manuel Kirchhof, Sanja Krause, Liam Rautenbach, Jakoba Wacker, Ann‐Katrin Beurer, Hoang‐Huy Nguyen, Wolfgang Frey, Yvonne Traa, Deven P. Estes, Anna Zens, Sabine Laschat   +10 more
wiley   +1 more source

Synthetic Strategies to Access Fluorinated Azoles

European Journal of Organic Chemistry, Volume 28, Issue 47, December 15, 2025.
This review highlights recent synthetic strategies for introducing fluorine groups (mono‐, di‐, and trifluoromethylation) into 11 major azole classes, identifying research gaps to inform future innovations in materials science, medicinal chemistry, and biomedical research.
Mohammed K. Abd El‐Gaber, Mario Djugovski, Tzu‐Yu Huang, Sweta Adhikari, Sudeshna Roy   +4 more
wiley   +1 more source

Von Sauerstoff zu Tellur: Der Einfluss des Chalkogenatoms auf die Nucleophilie und Basizität von Isochalkogenharnstoff‐basierten Katalysatoren

Angewandte Chemie, Volume 137, Issue 48, November 24, 2025.
Der Einbau verschiedener Chalkogenatome (O, S, Se oder Te) in häufig verwendete Isochalkogenharnstoff‐Organokatalysatoren ermöglicht die Feinabstimmung ihrer Nucleophilie und Basizität. Kinetische und thermodynamische Deskriptoren für die molekularen Eigenschaften der Katalysatoren werden als Werkzeuge zur Vorhersage ihrer Effizienz eingeführt und in ...
Lotte Stockhammer, Kevin Kasten, Andreas Eitzinger, Lukas S. Vogl, Magdalena Piringer, David Weinzierl, Armin R. Ofial, Andrew D. Smith, Mario Waser   +8 more
wiley   +1 more source

From Oxygen to Tellurium: The Impact of the Chalcogen on Nucleophilicities and Basicities of Isochalcogenourea Catalysts

Angewandte Chemie International Edition, Volume 64, Issue 48, November 24, 2025.
Incorporation of different chalcogen atoms allows for the fine‐tuning of nucleophilicity and basicity of commonly used isochalcogenourea organocatalyst scaffolds. Kinetic and thermodynamic descriptors for the molecular properties of the catalysts are introduced as tools to predict their efficiency and tested in acyl transfer and allenoate activation ...
Lotte Stockhammer, Kevin Kasten, Andreas Eitzinger, Lukas S. Vogl, Magdalena Piringer, David Weinzierl, Armin R. Ofial, Andrew D. Smith, Mario Waser   +8 more
wiley   +1 more source