Results 51 to 60 of about 1,216 (196)

Beiträge zur Koordinationschemie der Aziridine, 2H-Azirine und Phosphirane [PDF]

, 2008
This thesis contributes to the coordination chemistry of aziridines, 2H-azirines and P-mesitylphosphirane as ligands towards transition metals. The focus is set on transition metal halides and organometallic complexes of electron rich transition metals ...
Rödel, Nicolas
core   +1 more source

Addition and Cycloaddition Reactions of Phosphinyl- and Phosphonyl-2H-Azirines, Nitrosoalkenes and Azoalkenes

Molecules, 2009
An overview of the use of 2H-azirines, conjugated nitrosoalkenes and conjugated azoalkenes bearing phosphorus substituents in addition and cycloaddition reactions is presented, focused on strategies for the synthesis of aminophosphonate and ...
Américo Lemos
doaj   +1 more source

Strain Release of 1‐Azabicyclo[1.1.0]butanes as a Gateway to Highly Functionalized Azetidines: New Strategies and Structural Motifs

Chemistry – A European Journal, Volume 32, Issue 31, 18 August 2026.
Over the past decade, the interest in azetidines has continuously risen, by virtue of their highly appealing pharmaceutical properties. Monocyclic, spirocyclic, and bridged azetidines can be accessed by leveraging 1‐azabicyclo[1.1.0]butanes as precursors.
Yuri Gelato, Philipp Natho, Marco Colella, Renzo Luisi   +3 more
wiley   +1 more source

Synthesis of 2-Aminonicotinonitriles via Photodecarboxylation of Azirine-2-Carboxylic Acids

Molbank
2-Aminonicotinonitriles represent an important class of heterocycles with diverse biological activities. Herein, we report an unexpected photochemical transformation of azirine-2-carboxylic acids leading to the formation of 2-aminonicotinonitrile ...
Julia I. Pavlenko, Mikhail S. Novikov, Anastasiya V. Agafonova   +2 more
doaj   +1 more source

Photochemistry of N‐Substituted, N′‐Tosyl Diphenyl Sulfondiimines

Journal of Physical Organic Chemistry, Volume 39, Issue 8, August 2026.
The irradiation of N‐substituted, N′‐tosyl diphenyl sulfondiimines with UV light induces the sequential photorelease of two different nitrenes. ABSTRACT Sulfondiimines are an emerging sulfur(VI) functional group with increasing use in synthesis and medicinal chemistry, yet their photochemical behavior has remained largely unexplored.
Bashar Aziz, Paul Danyi, John P. Carney, Ryan D. McCulla   +3 more
wiley   +1 more source

Funktionalisierung von Peptiden auf der festen Phase im späten Synthesestadium

Angewandte Chemie, Volume 138, Issue 31, 27 July 2026.
Peptidmodifikationen sind für die Kontrolle der Eigenschaften von Peptidwirkstoffen von entscheidender Bedeutung. Daher sind Strategien, die einen effizienten und schnellen Einbau nicht‐kanonischer Modifikationen in Peptide in Parallelformaten ermöglichen, sehr gefragt.
Marius Werner, Truc Lam Pham, Franziska Thomas   +2 more
wiley   +1 more source

Asymmetric Synthesis of 2H-Azirine 3-Carboxylates

, 2016
Dehydrochlorination of methyl 2-chloroaziridine 2-carboxylates generates the first examples of enantiopure 2-substituted 2H-azirine 3-carboxylates which undergo the aza Diels−Alder reaction with dienes to give bicyclic and tricyclic aziridines in good ...
Franklin A. Davis (2108398), Jianghe Deng (1463092)   +1 more
core   +2 more sources

Late‐Stage Functionalization of Peptides on the Solid Phase

Angewandte Chemie International Edition, Volume 65, Issue 31, 27 July 2026.
Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner, Truc Lam Pham, Franziska Thomas   +2 more
wiley   +1 more source

Synthesis of Azirinylammonium Salts via Alkylation of DABCO with 2-Halo-2H-azirines

Molbank
Tertiary (2H-azirin-2-yl)ammonium salts were prepared from methyl 2-halo-3-aryl-2H-azirine-2-carboxylates and 1,4-diazabicyclo[2.2.2]octane in very good to excellent yields. Both iodide and bromide salts are stable enough in crystalline form to be stored
Maksim A. Valiarovskii, Alexander V. Vorob’ev, Anastasiya V. Agafonova, Mikhail S. Novikov   +3 more
doaj   +1 more source

(2‐Phosphinophenyl)aluminum Dichloride Complexes as Intramolecular Al/P Frustrated Lewis Pairs for Ketone, Ester, and Imine Activation

Chemistry – A European Journal, Volume 32, Issue 28, 25 July 2026.
Three 2‐phosphinophenylaluminum dichloride complexes were synthesized and characterized as novel intramolecular FLPs. These FLP systems exhibit high Lewis acidity and effectively activate challenging substrates including aliphatic ketones, imines, and esters. DFT analysis revealed that strain release and Al–P dynamics govern their reactivity. Abstract (
Yoshihiro Nishimoto, Hirotaka Okamoto, Makoto Yasuda   +2 more
wiley   +1 more source