Results 71 to 80 of about 1,216 (196)

Composite Single‐Reference and Explicitly Correlated Multireference Calculations on the Mechanism of Pyrrole Pyrolysis

Journal of Physical Organic Chemistry, Volume 39, Issue 4, April 2026.
New calculations have been applied to the pyrolysis of pyrrole under shock‐tube conditions and to the radical‐radical reaction between allyl and •CN at low temperature and pressure, using the same mechanistic scheme for both. ABSTRACT The pyrolysis of pyrrole has previously been studied in shock‐tube experiments and in jet‐stirred reactors. The results
Barry K. Carpenter
wiley   +1 more source

Cycloaddition of methyl 2-(2,6-dichorophenyl)-2H-azirine-3-carboxylate to electron rich 2-azadienes [PDF]

, 2003
Tert-Butyldimethylsililoxy-2-aza-1,3-butadienes react with 2H-azirine 3 leading to Diels-Alder cycloadducts in moderate yields. The reactions are endo- and regio- selective with the azirine being added by its less hindered face. There is only one product
Alves, M. José, Fortes, A. Gil, A. Gil Fortes, Durães, M. Miguel, M. Miguel Duraes, M. Jose Alves   +5 more
core   +1 more source

Synthesis of trifluoromethylated 2H-azirines through Togni reagent-mediated trifluoromethylation followed by PhIO-mediated azirination

Beilstein Journal of Organic Chemistry, 2018
The reaction of enamine compounds with the Togni reagent in the presence of CuI afforded β-trifluoromethylated enamine intermediates, which were converted directly to biologically interesting trifluoromethylated 2H-azirines by an iodosobenzene (PhIO ...
Jiyun Sun, Xiaohua Zhen, Huaibin Ge, Guangtao Zhang, Xuechan An, Yunfei Du   +5 more
doaj   +1 more source

Methyl (1aRS,7aSR)-7-formyl-1a-phenyl-1,1a-dihydroazirino[2,3-b]benzo[e][1,4]thiazine-7a(7H)-carboxylate

Molbank
The first representative of the aziridine-fused benzo[e][1,4]thiazine series was synthesized from methyl 2-bromo-2-phenyl-2H-azirine-2-carboxylate and benzo[d]thiazole in 74% yield.
Ilya P. Filippov, Anastasiya V. Agafonova, Nikolai V. Rostovskii, Mikhail S. Novikov   +3 more
doaj   +1 more source

Functionalized azirine based scaffolds as endothelin inhibitors for the selective anti-angiogenic activity

NoAnti-angiogenic therapy has long been used as an adjunct therapy for the resolution of tumor burden. The current findings describe the synthesis of novel marine-based azirine-containing compounds that exhibit anti-angiogenic mediated anti-tumor ...
Singh, A., Satish, N., Babu, T.R., Yadav, B., Siddiqui, M.I., Sudhakar, G., Singh, S.K., Wahajuddin, Singh, H., Jagavelu, K.   +9 more
core   +1 more source

Asymmetric radical additions of trialkylboranes to 2H-azirine-3-carboxylates

, 2004
Asymmetric additions of alkyl radicals, generated from R3B, to chiral 2H-azirine-3-carboxylates offer a new entry to enantio-enriched aziridines, and proceed with high diastereoselectivity when using 8-phenylmenthol as chiral auxiliary.
Fischer, Andreas,, Somfai, Peter,, Risberg, Erik,   +2 more
core   +1 more source

Nucleophile-Induced Rearrangement of 2H‑Azirine-2-carbonyl Azides to 2‑(1H‑Tetrazol-1-yl)acetic Acid Derivatives

, 2021
2H-Azirine-2-carbonyl azides undergo a rearrangement into derivatives of 2-(1H-tetrazol-1-yl)­acetic acid when interacting with O- and S-nucleophiles at room temperature. The reaction is catalyzed by tertiary amines or hydrazoic acid.
Dar’ya V. Spiridonova, Alexander F. Khlebnikov (1537960), Mikhail S. Novikov, Mikhail S. Novikov (1537957), Alexander F. Khlebnikov, Olesya A. Tomashenko (4241359), Olesya A. Tomashenko, Nikita I. Efimenko, Nikita I. Efimenko (11267198), Dar’ya V. Spiridonova (11267201)   +9 more
core   +1 more source

Diels–alder reactions of alkyl 2H-azirine-3-carboxylates with furans [PDF]

, 2001
Methyl 2-(2,6-dichlorophenyl)-2H-azirine-3-carboxylate 1 and furan give the aziridine 2 by a Diels–Alder cycloaddition reaction. The hydrolysis of compound 2 leads to a dihydrofuranol 11 by cleavage of a C–N bond.
Azóia, Nuno G., Alves, M. José, Bickley, Jamie F., Fortes, A. Gil, Gilchrist, Thomas L., Mendonça, Ricardo   +5 more
core   +1 more source

Asymmetric Synthesis of 2H-Azirine Carboxylic Esters by an Alkaloid-Mediated Neber Reaction

, 2016
Asymmetric Synthesis of 2H-Azirine Carboxylic Esters by an Alkaloid-Mediated Neber ...
Gerry J. A. Ariaans (2726719), Mariëlle M. H. Verstappen (2997459), Binne Zwanenburg (2529067)   +2 more
core   +1 more source

Non-natural 2H-azirine-2-carboxylic acids: an expedient synthesis and antimicrobial activity

, 2019
Non-natural 2H-azirine-2-carboxylic acids were obtained in high yields by FeCl2-catalyzed isomerization of 5-chloroisoxazoles to azirine-2-carbonyl chlorides followed by their hydrolysis.
Rogacheva, Elizaveta V., Kraeva, Liudmila A., Sakharov, Pavel A., Tennikova, Tatiana B., Sharoyko, Vladimir V., Rostovskii, Nikolai V., Koronatov, Alexander N., Khlebnikov, Alexander F., Novikov, Mikhail S., Glukharev, Artem G.   +9 more
core   +1 more source