Results 1 to 10 of about 18,845 (239)
Environmentally Friendly Synthesis of Polysubstituted Pyrroles in Ionic Liquid via Gold-Catalyzed Propargylic Substitution/Hydration/Amination/Cycloisomerization Sequence [PDF]
MoleculesAn environmentally friendly synthesis of polysubstituted pyrroles in ionic liquid was achieved via a gold-catalyzed propargylic substitution/hydration/amination/cycloisomerization sequence. Treatment of propargylic alcohols, 1,3-dicarbonyl compounds, and
Hitomi Chiaki +3 more
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Silver-catalyzed anionic [3 + 2] cycloaddition of benzyl isocyanides with polyfluoroalkylchromones and pyrones: direct synthesis of 2-arylpyrroles [PDF]
Beilstein Journal of Organic ChemistryA silver-catalyzed anionic [3 + 2] cycloaddition of benzyl isocyanides has been developed, providing direct one-pot access to 2-arylpyrroles – a privileged scaffold pervasive in medicinal chemistry and functional materials.
Ivan A. Kochnev, Alexey Yu. Barkov
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Synthesis of Novel Pyrroles and Fused Pyrroles as Antifungal and Antibacterial Agents
Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 Pyrroles and its fused forms possess antimicrobial activities, they can easily interact with biomolecules of living systems. A series of substituted pyrroles, and its fused pyrimidines and triazines forms have been synthesised, all newly synthesised ...
Zainab M Khoder +1 more
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Regioselective Stepwise Synthesis of Unsymmetrical 1,2,5-Triarylpyrroles via Palladium-Catalyzed Decarboxylative Cross-Coupling and C–H Arylation [PDF]
MoleculesPyrrole derivatives are natural organic molecules that are important to the pharmaceutical industry due to their occurrence in nature and their use in a wide range of medical applications. In general, non-symmetric, 1,2,5-triaryl-substituted pyrroles are
Cindy Buonomano +6 more
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Recent advances in the syntheses of pyrroles
Green Synthesis and Catalysis, 2023 The pyrrole moiety is an important structural motif in functional materials, natural products, and pharmaceuticals. More and more synthetic strategies toward pyrroles have emerged, where various efficient building blocks are developed and these synthons ...
Tao Shi +7 more
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Results in Chemistry, 2022 The first zinc-catalyzed simple and convenient protocol for the synthesis of N-substituted pyrroles through a modified Clauson-Kaas reaction without co-catalyst, ligand, base and solvent has been described.
C.M.A. Afsina, K.R. Rohit, G. Anilkumar
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Molecules, 2022 Herein, we describe the synthesis and characterization of fused pyrroles in cholestane and norcholestane side chains derived from kryptogenin and diosgenin, respectively.
María G. De los Santos +7 more
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An Easy Synthesis of Monofluorinated Derivatives of Pyrroles from β-Fluoro-β-Nitrostyrenes
Molecules, 2021 The catalyst-free conjugate addition of pyrroles to β-Fluoro-β-nitrostyrenes was investigated. The reaction was found to proceed under solvent-free conditions to form 2-(2-Fluoro-2-nitro-1-arylethyl)-1H-pyrroles.
Alexander S. Aldoshin +3 more
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BMJ Open Diabetes Research & Care, 2020 Introduction Progressive distal symmetrical axonal neuropathy, a complication of diabetes mellitus (DM), has an unknown cause. Normal physiological metabolism and diabetic dysmetabolism are associated with the generation of γ-diketones.
Wenting Feng +3 more
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Beilstein Journal of Organic Chemistry, 2021 The rhodium-catalyzed transannulation of N-perfluoroalkyl-1,2,3-triazoles with aromatic and aliphatic terminal alkynes under microwave heating conditions afforded N-perfluoroalkyl-3,4-disubstituted pyrroles (major products) and N-fluoroalkyl-2,4 ...
Olga Bakhanovich +3 more
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