Results 1 to 10 of about 105,049 (336)
Marine Pyrrole Alkaloids [PDF]
Marine Drugs, 2021 Nitrogen heterocycles are essential parts of the chemical machinery of life and often reveal intriguing structures. They are not only widespread in terrestrial habitats but can also frequently be found as natural products in the marine environment.
Till Opatz
exaly +5 more sources
Therapeutic potential of pyrrole and pyrrolidine analogs: an update
Molecular Diversity, 2022 The chemistry of nitrogen-containing heterocyclic compound pyrrole and pyrrolidine has been a versatile field of study for a long time for its diverse biological and medicinal importance .
Jeelan Basha N
exaly +2 more sources
Bioactive pyrrole-based compounds with target selectivity
European Journal of Medicinal Chemistry, 2020 The discovery of novel synthetic compounds with drug-like properties is an ongoing challenge in medicinal chemistry. Natural products have inspired the synthesis of compounds for pharmaceutical application, most of which are based on N-heterocyclic ...
Giovanna Li Petri +2 more
exaly +2 more sources
National Science Review, 2022 Rationally utilizing and developing synthetic units is of particular significance for the design of high-performance non-fullerene small-molecule acceptors (SMAs).
Tao Liu, Yang Zou, Chuluo Yang
exaly +2 more sources
Pyrrole: An insight into recent pharmacological advances with structure activity relationship
European Journal of Medicinal Chemistry, 2018 Pyrrole is a heterocyclic ring template with multiple pharmacophores that provides a way for the generation of library of enormous lead molecules. Owing to its vast pharmacological profile, pyrrole and its analogues have drawn much attention of the ...
Muzaffar Iqbal +2 more
exaly +2 more sources
Pyrrole: An emerging scaffold for construction of valuable therapeutic agents
European Journal of Medicinal Chemistry, 2016 Somnath Gholap
exaly +2 more sources
Correlation between levels of 2, 5-hexanedione and pyrrole adducts in tissues of rats exposure to n-hexane for 5-days. [PDF]
PLoS ONE, 2013 The formation of pyrrole adducts might be responsible for peripheral nerve injury caused by n-hexane. The internal dose of pyrrole adducts would supply more information for the neurotoxicity of n-hexane.
Hongyin Yin +4 more
doaj +1 more source
Biological exposure indices of pyrrole adducts in serum and urine for hazard assessment of n-hexane exposure. [PDF]
PLoS ONE, 2014 BACKGROUND: Pyrrole adducts might be used as a biomarker for monitoring occupational exposure to n-hexane, but the Biological Exposure Indices of pyrrole adducts in serum and urine are still unknown.
Hongyin Yin +6 more
doaj +1 more source
Pyrrole as an Important Scaffold of Anticancer Drugs: Recent Advances.
Journal of Pharmacy & Pharmaceutical Sciences, 2022 With the significant increase of patients suffering from different types of cancer, it is evident that prompt measures in the development of novel and effective agents need to be taken.
E. Mateev, M. Georgieva, A. Zlatkov
semanticscholar +1 more source
Molecules, 2020 A convenient two-step preparation of NH-free 5-aryl-pyrrole-2-carboxylates is described. The synthetic route consists of catalytic borylation of commercially available pyrrole-2-carboxylate ester followed by Suzuki coupling without going through pyrrole ...
Saba Kanwal +8 more
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