Results 41 to 50 of about 17,027 (206)

3,4-Bisthiolated Pyrroles: Concise Construction and Their Electronic Properties [PDF]

open access: yes, 2022
3,4-Bisthiolated pyrroles constitute key cores in pyrrole-based semiconductors, and their electronic properties could be improved by the bisthio groups via the S-effect.
Jun Tian   +11 more
core   +1 more source

Cycloaddition of Benzyne with Alkoxy-Substituted Pyrroline-N-oxides­: Unexpected Rearrangement to an N-Phenylpyrrole

open access: yesSynOpen, 2018
Reaction of enantiopure 3,4-dialkoxy-pyrroline N-oxides with benzyne affords the expected tetrahydrobenzo[d]pyrrolo[1,2-b]isoxazoles along with an unexpected 2,3-disubstitued-N-phenyl-pyrrole derived from an unprecedented rearrangement of the adduct of ...
Franca M. Cordero   +3 more
doaj   +1 more source

Microwave-assisted polystyrene sulfonatecatalyzed synthesis of novel pyrroles [PDF]

open access: yes, 2012
Background: Pyrroles are widely distributed in nature and important biologically active molecules. The reaction of amines with 2,5-dimethoxytetrahydrofuran is a promising pathway for the synthesis of pharmacologically active pyrroles under microwave ...
Reddy, Ashwini   +4 more
core   +2 more sources

Synthesis and Pharmacochemistry of New Pleiotropic Pyrrolyl Derivatives

open access: yesMolecules, 2015
Within the framework of our attempts to synthesize pleiotropic anti-inflammatory agents, we have synthesized some chalcones and their corresponding 3,4-pyrrolyl derivatives. Chalcones constitute a class of compounds with high biological impact.
Markella Konstantinidou   +2 more
doaj   +1 more source

Antifungal Activity of Fibrate-Based Compounds and Substituted Pyrroles That Inhibit the Enzyme 3-Hydroxy-methyl-glutaryl-CoA Reductase of Candida glabrata (CgHMGR), Thus Decreasing Yeast Viability and Ergosterol Synthesis

open access: yesMicrobiology Spectrum, 2022
Due to the emergence of multidrug-resistant strains of yeasts belonging to the Candida genus, there is an urgent need to discover antifungal agents directed at alternative molecular targets.
Damián A. Madrigal-Aguilar   +10 more
doaj   +1 more source

The Synthesis of Pyrroles from Nitroolefins

open access: yesЖурнал органічної та фармацевтичної хімії
The synthesis of pyrroles occupies a key place in synthetic organic chemistry due to the numerous biological properties of pyrrole derivatives, in particular antimicrobial, antibacterial, antifungal, antimalarial, anticancer activities, etc.
Andrii H. Hotynchan   +2 more
doaj   +1 more source

Synthetic Approaches to the Lamellarins—A Comprehensive Review

open access: yesMarine Drugs, 2014
The present review discusses the known synthetic routes to the lamellarin alkaloids published until 2014. It begins with syntheses of the structurally simpler type-II lamellarins and then focuses on the larger class of the 5,6-saturated and -unsaturated ...
Dennis Imbri   +2 more
doaj   +1 more source

Recent Strides in the Transition Metal-Free Cross-Coupling of Haloacetylenes with Electron-Rich Heterocycles in Solid Media

open access: yesMolecules, 2020
The publications covering new, transition metal-free cross-coupling reactions of pyrroles with electrophilic haloacetylenes in solid medium of metal oxides and salts to regioselectively afford 2-ethynylpyrroles are discussed.
Lyubov’ N. Sobenina, Boris A. Trofimov
doaj   +1 more source

Direct Synthesisof Pyrroles by Decarboxylative Ethynyl Methylene Cyclic Carbamates (EMCCs) and Amines Catalyzed by a Binuclear Copper Complexe [PDF]

open access: yes
An efficient, facile and practical one-pot procedure for the synthesis of polysubstituted pyrroles catalyzed by a binuclear copper complexe using EMCCs as precursors for generating 2-aminoallyl cations was firstly demonstrated.
Shi-Wu, Li, Yujie, Zhao
core   +1 more source

Aroylation of Electron-Rich Pyrroles under Minisci Reaction Conditions [PDF]

open access: yes, 2020
The development of Minisci acylation on electron-rich pyrroles under silver-free neutral conditions has been reported featuring the regioselective monoacylation of (NH)-free pyrroles. Unlike conventional Minisci conditions, the avoidance of any acid that
Mandeep Kaur Hunjan (4236151)   +3 more
core   +1 more source

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