Results 41 to 50 of about 18,411 (287)

Recent advances in the synthesis of pyrroles [PDF]

, 2020
Pyrroles are the most prevalent heterocyclic compounds, which are present as the basic cores in many natural products, such as vitamin B12, bile pigments like bilirubin and biliverdin, the porphyrins of heme, chlorophyll, chlorins, bacteriochlorins, and ...
Rasheed, Hina, Mukhtar, Asma, Awan, Rabiya Javed, Awan, Ramsha Javed, Iqbal, Sarosh, Moloney, Mark G   +5 more
core   +1 more source

[3+3]-Annulation of Cyclic Nitronates with Vinyl Diazoacetates: Diastereoselective Synthesis of Partially Saturated [1,2]Oxazino[2,3-b][1,2]oxazines and Their Base-Promoted Ring Contraction to Pyrrolo[1,2-b][1,2]oxazine Derivatives

Molecules, 2023
A rhodium(II)-catalyzed reaction of cyclic nitronates (5,6-dihydro-4H-1,2-oxazine N-oxides) with vinyl diazoacetates proceeds as a [3+3]-annulation producing bicyclic unsaturated nitroso acetals (4a,5,6,7-tetrahydro-2H-[1,2]oxazino[2,3-b][1,2]oxazines ...
Yulia A. Antonova, Yulia V. Nelyubina, Sema L. Ioffe, Andrey A. Tabolin   +3 more
doaj   +1 more source

Cycloaddition of Benzyne with Alkoxy-Substituted Pyrroline-N-oxides­: Unexpected Rearrangement to an N-Phenylpyrrole

SynOpen, 2018
Reaction of enantiopure 3,4-dialkoxy-pyrroline N-oxides with benzyne affords the expected tetrahydrobenzo[d]pyrrolo[1,2-b]isoxazoles along with an unexpected 2,3-disubstitued-N-phenyl-pyrrole derived from an unprecedented rearrangement of the adduct of ...
Franca M. Cordero, Bhushan B. Khairnar, Anna Ranzenigo, Alberto Brandi   +3 more
doaj   +1 more source

Synthesis and Pharmacochemistry of New Pleiotropic Pyrrolyl Derivatives

Molecules, 2015
Within the framework of our attempts to synthesize pleiotropic anti-inflammatory agents, we have synthesized some chalcones and their corresponding 3,4-pyrrolyl derivatives. Chalcones constitute a class of compounds with high biological impact.
Markella Konstantinidou, Alice Gkermani, Dimitra Hadjipavlou-Litina   +2 more
doaj   +1 more source

Antifungal Activity of Fibrate-Based Compounds and Substituted Pyrroles That Inhibit the Enzyme 3-Hydroxy-methyl-glutaryl-CoA Reductase of Candida glabrata (CgHMGR), Thus Decreasing Yeast Viability and Ergosterol Synthesis

Microbiology Spectrum, 2022
Due to the emergence of multidrug-resistant strains of yeasts belonging to the Candida genus, there is an urgent need to discover antifungal agents directed at alternative molecular targets.
Damián A. Madrigal-Aguilar, Adilene Gonzalez-Silva, Blanca Rosales-Acosta, Celia Bautista-Crescencio, Jossué Ortiz-Álvarez, Carlos H. Escalante, Jaime Sánchez-Navarrete, César Hernández-Rodríguez, Germán Chamorro-Cevallos, Joaquín Tamariz, Lourdes Villa-Tanaca   +10 more
doaj   +1 more source

The Synthesis of Pyrroles from Nitroolefins

Журнал органічної та фармацевтичної хімії
The synthesis of pyrroles occupies a key place in synthetic organic chemistry due to the numerous biological properties of pyrrole derivatives, in particular antimicrobial, antibacterial, antifungal, antimalarial, anticancer activities, etc.
Andrii H. Hotynchan, Olena M. Kovtun, Yuriy P. Kovtun   +2 more
doaj   +1 more source

Synthetic Approaches to the Lamellarins—A Comprehensive Review

Marine Drugs, 2014
The present review discusses the known synthetic routes to the lamellarin alkaloids published until 2014. It begins with syntheses of the structurally simpler type-II lamellarins and then focuses on the larger class of the 5,6-saturated and -unsaturated ...
Dennis Imbri, Johannes Tauber, Till Opatz   +2 more
doaj   +1 more source

Recent Strides in the Transition Metal-Free Cross-Coupling of Haloacetylenes with Electron-Rich Heterocycles in Solid Media

Molecules, 2020
The publications covering new, transition metal-free cross-coupling reactions of pyrroles with electrophilic haloacetylenes in solid medium of metal oxides and salts to regioselectively afford 2-ethynylpyrroles are discussed.
Lyubov’ N. Sobenina, Boris A. Trofimov
doaj   +1 more source

Spatial separation of pyrrole and pyrrole-water clusters [PDF]

Chemical Physics Letters, 2019
We demonstrate the spatial separation of pyrrole and pyrrole(H$_2$O) clusters from the other atomic and molecular species in a supersonically-expanded beam of pyrrole and traces of water seeded in high-pressure helium gas. The experimental results are quantitatively supported by simulations.
Johny, Melby, Onvlee, Jolijn, Kierspel, Thomas, Bieker, Helen, Trippel, Sebastian, Küpper, Jochen   +5 more
openaire   +5 more sources

Direct Synthesisof Pyrroles by Decarboxylative Ethynyl Methylene Cyclic Carbamates (EMCCs) and Amines Catalyzed by a Binuclear Copper Complexe [PDF]

An efficient, facile and practical one-pot procedure for the synthesis of polysubstituted pyrroles catalyzed by a binuclear copper complexe using EMCCs as precursors for generating 2-aminoallyl cations was firstly demonstrated.
Shi-Wu, Li, Yujie, Zhao
core   +2 more sources