A catalyst-controlled selective synthesis of pyridines and pyrroles [PDF]
We have developed a dual reaction manifold that enables selective synthesis of both pyridines and pyrroles from common substrates ??-diazo oxime ethers.
Alvarez-Corral +55 more
core +1 more source
Detection of reactive oxygen and nitrogen species by electron paramagnetic resonance (EPR) technique [PDF]
During the last decade there has been growing interest in physical-chemical oxidation processes and the behavior of free radicals in living systems. Radicals are known as intermediate species in a variety of biochemical reactions.
Gurer-Orhan, H., Saso, L., Suzen, S.
core +2 more sources
Synthesis and Reactivity of New 1-Pentafluorophenyl-1Hpyrrole Derivatives
We present 1-pentafluorophenyl-1H-pyrrole and some of its electrophilic substitution reactions: formylation and acetylations. The 2-substituted products formed in these reactions are selectively and in high yield converted into 3-substituted products by ...
Daniel Végh +1 more
doaj +1 more source
A Novel Indium-Catalyzed Three-Component Reaction: General and Efficient One-Pot Synthesis of Substituted Pyrroles [PDF]
A convenient and general approach towards the synthesis of substituted pyrroles from propargylic acetates, silyl enol ethers, and primary amines was described. This novel transformation was catalyzed by indium trichloride in a one-pot synthesis, and high
Hao, Lu +4 more
core +1 more source
Diethyl pyrrole-2,5-dicarboxylate [PDF]
The title compound was obtained in moderate yield by a new and unexpected base-induced ring contraction from a 1,4-thiazine precursor. Its X-ray structure showing hydrogen bonded dimers was compared with those of other crystallographically characterised 2-acylpyrroles.
R. Alan Aitken +3 more
openaire +4 more sources
A one-step, three-component reaction between α-hydroxyketones, oxoacetonitriles, and primary amines gives N-substituted 2,3,5-functionalized 3-cyanopyrroles with complete selectivity in up to 90% isolated yields.
Mengxin Xia +2 more
doaj +1 more source
Synthesis of pi-conjugated systems bearing thiophene and pyrrole heterocycles through palladium catalyzed cross-coupling reactions. [PDF]
A series of thienylpyrroles and bithienylpyrroles together with their formyl derivatives 5aed were synthesized using commercially or readily available coupling components, through three different palladium catalyzed cross-coupling reactions (Suzuki ...
Castro, M. +2 more
core +1 more source
Synthesis of novel pyrroles and fused pyrroles as antifungal and antibacterial agents
Pyrroles and its fused forms possess antimicrobial activities, they can easily interact with biomolecules of living systems. A series of substituted pyrroles, and its fused pyrimidines and triazines forms have been synthesised, all newly synthesised ...
Rania Helmy Abd El-Hameed +5 more
doaj +1 more source
Development of Novel Pyrrole Derivatives and Their Cinnamic Hybrids as Dual COX-2/LOX Inhibitors
Molecular hybridization has emerged as a promising approach in the treatment of diseases exhibiting multifactorial etiology. With regard to this, dual cyclooxygenase-2/lipoxygenase (COX-2/LOX) inhibitors could be considered a safe alternative to ...
Viola Noti +2 more
doaj +1 more source
Methyl 2-amino-5-isopropyl-1,3-thiazole-4-carboxylate [PDF]
The title compound, C8H12N2O2S, forms a supramolecular network based on N-HN hydrogen-bonded centrosymmetric dimers that are linked in turn by N-HO ...
Kennedy, Alan R. +3 more
core +1 more source

