Results 51 to 60 of about 17,027 (206)

Tetrasubstituted Pyrrole Derivative Mimetics of Protein–Protein Interaction Hot-Spot Residues: A Promising Class of Anticancer Agents Targeting Melanoma Cells

open access: yesMolecules, 2023
A new series of tetrasubstituted pyrrole derivatives (TSPs) was synthesized based on a previously developed hypothesis on their ability to mimic hydrophobic protein motifs.
Marco Persico   +12 more
doaj   +1 more source

Synthesis and Anti-Tuberculosis Activity of Substituted 3,4-(dicoumarin-3-yl)-2,5-diphenyl Furans and Pyrroles

open access: yesEngineering Proceedings, 2022
Increasing rates of multi-drug resistant (MDR) and extremely-drug resistant (XDR) cases of tuberculosis (TB) strains are alarming, and eventually hampered an effective control of the pathogenic disease. In the present study, nine derivatives of 2,3-bis(2-
Bhagwat Jadhav   +2 more
doaj   +1 more source

Alkylation of β-(Hydroxymethyl)pyrroles:  A New Synthesis of Porphobilinogen and Other Trisubstituted Pyrroles for Photodynamic Therapy [PDF]

open access: yes, 2016
Alkylation of β-(Hydroxymethyl)pyrroles:  A New Synthesis of Porphobilinogen and Other Trisubstituted Pyrroles for Photodynamic ...
Bruce Ganem (2198635)   +1 more
core   +1 more source

Copper-Catalyzed Cycloisomerization of Cyclopropenylimine for Synthesis of Pyrroles [PDF]

open access: yes, 2019
Copper-catalyzed cycloisomerization of 3-iminocyclopropenes for synthesis of pyrroles has been developed. The reaction allows regioselective construction of pyrroles with various substitution patterns, including fully substituted pyrroles. The method was
Okiko Miyata (1883341)   +5 more
core   +1 more source

Phosphate complexes of calix[4]pyrroles [PDF]

open access: yes, 2020
This bachelor’s thesis is about the structure and the properties of different calix[4]pyrroles. Specifically, the binding of calix[4]pyrroles with different phosphate-containing molecules is assessed.
Naulapää, Julia
core  

Spatial separation of pyrrole and pyrrole-water clusters [PDF]

open access: yesChemical Physics Letters, 2019
Chemical physics letters 721, 149 - 152 (2019).
Johny, Melby   +5 more
openaire   +5 more sources

Physical properties of alkyl pyrroles and their salts [PDF]

open access: yes, 1959
The structures of the ions formed by several alkyl pyrroles in hydrochloric acid are deduced from proton resonance spectra. Basicity values for three alkyl pyrroles are determined from ultraviolet spectra of their salts in buffer solutions. An attempt is
Bullock, E.   +5 more
core   +1 more source

Synthesis and practical applications of 2-(2-nitroalkyl)pyrroles [PDF]

open access: yes, 2020
Functionalization of pyrroles introducing a 2-nitroalkyl moiety allows the formation of nitro-containing compounds to be used as pivotal intermediates for the synthesis of bioactive compounds.
Palmieri, A, Petrini, M
core   +1 more source

Substituent-Dependent Divergent Synthesis of 2-(3-Amino-2,4-dicyanophenyl)pyrroles, Pyrrolyldienols and 3-Amino-1-acylethylidene-2-cyanopyrrolizines via Reaction of Acylethynylpyrroles with Malononitrile

open access: yesMolecules, 2022
An efficient method for the synthesis of pharmaceutically and high-tech prospective 2-(3-amino-2,4-dicyanophenyl)pyrroles (in up to 88% yield) via the reaction of easily available substituted acylethynylpyrroles with malononitrile has been developed. The
Maxim D. Gotsko   +4 more
doaj   +1 more source

Synthesis and reactivity of 2-thionoester pyrroles: a route to 2-formyl pyrroles [PDF]

open access: yes, 2019
2-Functionalised pyrroles exhibit considerable synthetic utility. Herein, the synthesis and reactivity of 2-thionoester (-C(S)OR) pyrroles is reported. 2-Thionoester pyrroles were synthesized using a Knorr-type approach from aliphatic starting materials.
Kim, Min Joon   +4 more
core  

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