Results 21 to 30 of about 17,027 (206)
Selectively reductive amination of levulinic acid with aryl amines to N-substituted aryl pyrroles
Green Energy & Environment, 2023 Synthesizing nitrogen (N)-containing molecules from biomass derivatives is a new strategy for production of this kind of chemicals. Herein, for the first time we present the synthesis of N-substituted aryl pyrroles via reductive amination/cyclization of ...
Cailing Wu +7 more
doaj +1 more source
Atom Economical Multi-Substituted Pyrrole Synthesis from Aziridine
Molecules, 2022 Multi-substituted pyrroles are synthesized from regiospecific aziridine ring-opening and subsequent intramolecular cyclization with a carbonyl group at the γ-position in the presence of Lewis acid or protic acid.
Lingamurthy Macha +3 more
doaj +1 more source
Synthesis of Tetrasubstituted Pyrroles from Terminal Alkynes and Imines [PDF]
, 2013 Tetrasubstituted pyrroles can be obtained via the reaction of terminal alkynes and Imines using (BuLi)-Bu-n as the base In one step with high chemoselectivity (method 1).
Wu, Fan +5 more
core +1 more source
Electrochemically Induced N-Alkylation of Pyrroles [PDF]
, 1999 Electrochemically generated tetraethylammonium peroxy- corresponding N-alkylated pyrroles in high yields. C- Alkylated pyrroles have not been isolated in any casedicarbonate (TEAPC) and tetraethylammonium carbonate (TEAC) react under very mild ...
FEROCI, Marta +3 more
core +3 more sources
Effect of Substituents of Cerium Pyrazolates and Pyrrolates on Carbon Dioxide Activation
Molecules, 2021 Homoleptic ceric pyrazolates (pz) Ce(RR’pz)4 (R = R’ = tBu; R = R’ = Ph; R = tBu, R’ = Me) were synthesized by the protonolysis reaction of Ce[N(SiHMe2)2]4 with the corresponding pyrazole derivative.
Uwe Bayer +4 more
doaj +1 more source
Photocatalytic Alkylation of Pyrroles and Indoles with α-Diazo Esters [PDF]
, 2019 This article describes direct photoalkylation of electron-rich aromatic compounds with diazo compoiunds. C-2 alkylated indoles and pyrroles are obtained with good yields even though the photocatalyst (Ru(bpy)3Cl2) loading is as low as 0.075 mol %.
Jakub, Durka +2 more
core +1 more source
Cancer Medicine, 2023 Background Activating mutations of the KRAS occurs in >90% of pancreatic ductal adenocarcinoma (PDAC) cases. However, direct pharmacological targeting of the activated KRAS protein has been challenging.
Akiko Tsujimoto +10 more
doaj +1 more source
Pharmaceuticals, 2021 Nocodazole is an antineoplastic agent that exerts its effects by depolymerizing microtubules. Herein we report a structural analog of nocodazole, a (1H-pyrrol-1-yl)methyl-1H-benzoimidazole carbamate ester derivative, named RDS 60.
Alice Nicolai +14 more
doaj +1 more source
Identification of damaged proteins in human serum using modified Ehrlich's reagent to target protein-bound pyrroles [PDF]
, 2010 Peer ...
Rucklidge, Garry Jonathan +4 more
core +1 more source
Molecules, 2023 A simple and concise three-component synthesis of a key pyrrole framework was developed from the reaction between α-hydroxyketones, oxoacetonitriles, and anilines.
Mengxin Xia +3 more
doaj +1 more source