Results 21 to 30 of about 26,582 (202)

Synthesis and Recognition Properties of Higher Order Tetrathiafulvalene (Ttf) Calix N Pyrroles (N=4-6) [PDF]

, 2012
Two new benzoTTF-annulated calix[n]pyrroles (n = 5 and 6) were synthesized via a one-step acid catalyzed condensation reaction and fully characterized via single crystallographic analyses.
Bejger, Christopher, Jana, Atanu, Jeppesen, Jan O., Kim, Dongho, Larsen, Karina R., Lynch, Vincent M., Nielsen, Kent A., Park, Jung Su, Sessler, Jonathan L.   +8 more
core   +1 more source

Effect of Substituents of Cerium Pyrazolates and Pyrrolates on Carbon Dioxide Activation

Molecules, 2021
Homoleptic ceric pyrazolates (pz) Ce(RR’pz)4 (R = R’ = tBu; R = R’ = Ph; R = tBu, R’ = Me) were synthesized by the protonolysis reaction of Ce[N(SiHMe2)2]4 with the corresponding pyrazole derivative.
Uwe Bayer, Adrian Jenner, Jonas Riedmaier, Cäcilia Maichle-Mössmer, Reiner Anwander   +4 more
doaj   +1 more source

Counterion effects in iminium-activated electrophilic aromatic substitutions of pyrroles. [PDF]

, 2011
Electrophilic substitution of pyrroles by a,b-unsaturated iminium ions is slow in acetonitrile when only weakly basic counterions are present. When the reactions are carried out in the presence of KCF3CO2, fast deprotonation of the intermediate r-adducts
Albert, Almaşi, Benfatti, Brazier, Brazier, Brown, Capdevila, Cozzi, Erkkilä, Fleischer, Gordillo, Groselj, Groselj, Herbert Mayr, Lakhdar, Lakhdar, Lakhdar, Lelais, List, Mayr, Mayr, Mayr, Mayr, Mayr, Nigst, Paras, Sami Lakhdar, Seayad, Seebach, Seebach, Sparr, Sparr, Terrasson, Tsogoeva   +33 more
core   +1 more source

Anti-Tumoral Effects of a (1H-Pyrrol-1-yl)Methyl-1H-Benzoimidazole Carbamate Ester Derivative on Head and Neck Squamous Carcinoma Cell Lines

Pharmaceuticals, 2021
Nocodazole is an antineoplastic agent that exerts its effects by depolymerizing microtubules. Herein we report a structural analog of nocodazole, a (1H-pyrrol-1-yl)methyl-1H-benzoimidazole carbamate ester derivative, named RDS 60.
Alice Nicolai, Valentina Noemi Madia, Antonella Messore, Daniela De Vita, Alessandro De Leo, Davide Ialongo, Valeria Tudino, Elisabetta Tortorella, Luigi Scipione, Samanta Taurone, Tiziano Pergolizzi, Marco Artico, Roberto Di Santo, Roberta Costi, Susanna Scarpa   +14 more
doaj   +1 more source

Flexible synthesis of polyfunctionalised 3-fluoropyrroles [PDF]

, 2016
An efficient and selective approach for the synthesis of polyfunctionalised 3-fluoropyrroles has been developed starting from commercial aldehydes.
Cogswell, Thomas J., Donald, Craig S., Marquez, Rodolfo   +2 more
core   +1 more source

Lower levels of damaged protein biomarkers in the plasma of overweight type 2 diabetic men following supplementation with a standardised bilberry extract [PDF]

, 2012
Peer reviewedPublisher ...
Campbell, F. M., Cruickshank, M., Hoggard, N., Moar, K-M., Nicol, P. F.   +4 more
core   +1 more source

Use of DNA‐alkylating pyrrole‐imidazole polyamides for anti‐cancer drug sensitivity screening in pancreatic ductal adenocarcinoma

Cancer Medicine, 2023
Background Activating mutations of the KRAS occurs in >90% of pancreatic ductal adenocarcinoma (PDAC) cases. However, direct pharmacological targeting of the activated KRAS protein has been challenging.
Akiko Tsujimoto, Niina Matsuo, Xiaoyi Lai, Takahiro Inoue, Hiroyuki Yoda, Jason Lin, Yoshinao Shinozaki, Takayoshi Watanabe, Nobuko Koshikawa, Atsushi Takatori, Hiroki Nagase   +10 more
doaj   +1 more source

A Concise Synthesis of Pyrrole-Based Drug Candidates from α-Hydroxyketones, 3-Oxobutanenitrile, and Anilines

Molecules, 2023
A simple and concise three-component synthesis of a key pyrrole framework was developed from the reaction between α-hydroxyketones, oxoacetonitriles, and anilines.
Mengxin Xia, Mardi Santoso, Ziad Moussa, Zaher M. A. Judeh   +3 more
doaj   +1 more source

Regioselective Formation of α-Vinylpyrroles from the Ruthenium-Catalyzed Coupling Reaction of Pyrroles and Terminal Alkynes Involving C–H Bond Activation [PDF]

, 2010
The cationic ruthenium catalyst Ru3(CO)12/NH4PF6 was found to be highly effective for the intermolecular coupling reaction of pyrroles and terminal alkynes to give gem-selective α-vinylpyrroles.
Gao, Ruili, Yi, Chae S.
core   +2 more sources

Remarkable Iodine-Catalyzed Synthesis of Novel Pyrrole- Bearing N-Polyaromatic β-Lactams

Molecules, 2010
Because of their interesting biological properties various methods for the synthesis of substituted pyrroles are described in the literature. However, synthesis of pyrroles fused with a β-lactam ring has not been reported.
Bimal K. Banik, Hector Aguilar, Isabel Salinas, Gildardo Rivera, Debasish Bandyopadhyay   +4 more
doaj   +1 more source