Results 21 to 30 of about 18,845 (239)

Remarkable Iodine-Catalyzed Synthesis of Novel Pyrrole- Bearing N-Polyaromatic β-Lactams

Molecules, 2010
Because of their interesting biological properties various methods for the synthesis of substituted pyrroles are described in the literature. However, synthesis of pyrroles fused with a β-lactam ring has not been reported.
Bimal K. Banik, Hector Aguilar, Isabel Salinas, Gildardo Rivera, Debasish Bandyopadhyay   +4 more
doaj   +1 more source

A Concise Synthesis of Pyrrole-Based Drug Candidates from α-Hydroxyketones, 3-Oxobutanenitrile, and Anilines

Molecules, 2023
A simple and concise three-component synthesis of a key pyrrole framework was developed from the reaction between α-hydroxyketones, oxoacetonitriles, and anilines.
Mengxin Xia, Mardi Santoso, Ziad Moussa, Zaher M. A. Judeh   +3 more
doaj   +1 more source

[3+2] Cycloaddition of Tosylmethyl Isocyanide with Styrylisoxazoles: Facile Access to Polysubstituted 3-(Isoxazol-5-yl)pyrroles

Molecules, 2017
A facile access to polysubstituted 3-(isoxazol-5-yl)pyrroles was developed through [3+2] cycloaddition of tosylmethyl isocyanide (TosMIC) and styrylisoxazoles.
Xueming Zhang, Xianxiu Xu, Dawei Zhang
doaj   +1 more source

Novel Structural Hybrids of Pyrrole and Thiazole Moieties: Synthesis and Evaluation of Antibacterial and Antifungal Activities

Acta Chimica Slovenica, 2021
One of the best ways to design new biocidal agents is synthesizing hybrid molecules by combining two or more bioactive moieties in a single molecular scaffold.
Mohamed Salem, Samir Abbas, Marwa El-Sharief, Mohamed Helal, Moustafa Gouda, Mohammed Assiri, Mohammed Assiri, Tarik Ali, Tarik Ali   +8 more
doaj   +1 more source

An Efficient Synthesis of Aryl-Substituted Pyrroles by the Suzuki–Miyaura Coupling Reaction of SEM-Protected Pyrroles

Molecules, 2019
An efficient arylation of SEM-protected pyrroles by the Suzuki–Miyaura coupling reaction has been developed. The reaction can be carried out under mild conditions to provide aryl-substituted pyrroles in moderate to excellent yields.
Keli Cui, Meng Gao, Hongyi Zhao, Dongfeng Zhang, Hong Yan, Haihong Huang   +5 more
doaj   +1 more source

Cycloaddition of Benzyne with Alkoxy-Substituted Pyrroline-N-oxides­: Unexpected Rearrangement to an N-Phenylpyrrole

SynOpen, 2018
Reaction of enantiopure 3,4-dialkoxy-pyrroline N-oxides with benzyne affords the expected tetrahydrobenzo[d]pyrrolo[1,2-b]isoxazoles along with an unexpected 2,3-disubstitued-N-phenyl-pyrrole derived from an unprecedented rearrangement of the adduct of ...
Franca M. Cordero, Bhushan B. Khairnar, Anna Ranzenigo, Alberto Brandi   +3 more
doaj   +1 more source

Synthesis and Pharmacochemistry of New Pleiotropic Pyrrolyl Derivatives

Molecules, 2015
Within the framework of our attempts to synthesize pleiotropic anti-inflammatory agents, we have synthesized some chalcones and their corresponding 3,4-pyrrolyl derivatives. Chalcones constitute a class of compounds with high biological impact.
Markella Konstantinidou, Alice Gkermani, Dimitra Hadjipavlou-Litina   +2 more
doaj   +1 more source

[3+3]-Annulation of Cyclic Nitronates with Vinyl Diazoacetates: Diastereoselective Synthesis of Partially Saturated [1,2]Oxazino[2,3-b][1,2]oxazines and Their Base-Promoted Ring Contraction to Pyrrolo[1,2-b][1,2]oxazine Derivatives

Molecules, 2023
A rhodium(II)-catalyzed reaction of cyclic nitronates (5,6-dihydro-4H-1,2-oxazine N-oxides) with vinyl diazoacetates proceeds as a [3+3]-annulation producing bicyclic unsaturated nitroso acetals (4a,5,6,7-tetrahydro-2H-[1,2]oxazino[2,3-b][1,2]oxazines ...
Yulia A. Antonova, Yulia V. Nelyubina, Sema L. Ioffe, Andrey A. Tabolin   +3 more
doaj   +1 more source

The Synthesis of Pyrroles from Nitroolefins

Журнал органічної та фармацевтичної хімії
The synthesis of pyrroles occupies a key place in synthetic organic chemistry due to the numerous biological properties of pyrrole derivatives, in particular antimicrobial, antibacterial, antifungal, antimalarial, anticancer activities, etc.
Andrii H. Hotynchan, Olena M. Kovtun, Yuriy P. Kovtun   +2 more
doaj   +1 more source

Synthetic Approaches to the Lamellarins—A Comprehensive Review

Marine Drugs, 2014
The present review discusses the known synthetic routes to the lamellarin alkaloids published until 2014. It begins with syntheses of the structurally simpler type-II lamellarins and then focuses on the larger class of the 5,6-saturated and -unsaturated ...
Dennis Imbri, Johannes Tauber, Till Opatz   +2 more
doaj   +1 more source