Results 41 to 50 of about 3,434 (226)
Synthesis of Z-Protected Aib- and Phe(2Me)-Containing Pentapeptides and Their Crystal Structures [PDF]
A series of pentapeptide derivatives containing alpha,alpha-disubstituted alpha-amino acids have been prepared by a combination of the 'azirine/oxazolone method' and segment condensations.
Arnhold, Franziska S +2 more
core +1 more source
Bildung eines Azacyclols durch transanulare Ringkontraktion
Reaction of 3-dimethylamino-2,2-dimethyl-2H-azirine (1) with phthalimide (8) in polar solvents yields the (1:1)-adduct 2-dimethylamino-9b-hydroxy-3,3-dimethyl-5,9b-dihydro-3H-imidazo[2,1-a]isoindol-5-one (10).
Marlise Schläpfer-Dähler +4 more
doaj +1 more source
2-Methylsulfanylbenzo[f]isoquinoline [PDF]
S-Methylation of a 4-(naphth-2-yl)-β-thiolactam gives an intermediate 4-(naphth-2-yl) substituted 1-azetine which undergoes a [2+2] ring-opening followed by electrocyclic ring closure of the resulting 2-azadiene to give a benzo[f ...
Hemming, Karl +2 more
core +2 more sources
3-Dimethylamino-2,2-dimethyl-2H-azirine (1) and 5-trifluoromethyl-1,3,4- oxadiazol-2(3H)-on (9) in 2-propanol react already at room temperature to give the dipolar compound 10 in reasonable yield (Scheme 4).
Roland Prewo +2 more
doaj +1 more source
Benzene derivatives produced by Fusarium graminearum — Short communication [PDF]
Using NMR spectroscopy benzene derivatives were detected in mycelia of Fusarium graminearum, a pathogen of wheat and maize. In previous studies F. graminearum was found to cause cancer to humans and benzene derivatives were detected in breath of cancer ...
Ntushelo, Khayalethu +1 more
core +1 more source
Primary sclerosing cholangitis (PSC) is a chronic inflammatory disease of the bile ducts that has been associated with diverse metabolic carboxylic acids. Mass spectrometric techniques are the method of choice for their analysis.
Weifeng Lin +5 more
semanticscholar +1 more source
Neuere Methoden zur Ringerweiterung organischer Verbindungen
The actual interest in the construction of cyclic compounds via ring expansion reactions is demonstrated in the first chapter by means of typical examples.
Heinz Heimgartner
doaj +1 more source
CuH-Catalyzed Regioselective Intramolecular Hydroamination for the Synthesis of Alkyl-Substituted Chiral Aziridines [PDF]
This report details a general and enantioselective means for the synthesis of alkyl-substituted aziridines. This protocol offers a direct route for the synthesis of alkyl-substituted chiral aziridines from achiral starting materials.
Wang, Haoxuan +2 more
core +1 more source
Kristallstruktur eines 2-Dimethylamino-3,3-dimethyl-4(3H)-pyridons
3-Dimethylamino-2,2-dimethyl-2H-azirine (1) reacts with alkyl phenyl substituted cyclopropenones 2 in benzene at 130 °C to give a mixture of the two isomeric 4(3H)-pyridones 3 and 4, resulting from a nucleophilic attack at C(2) and C(1) of the ...
Jost H. Bieri +2 more
doaj +1 more source
Global membrane protein interactome analysis using in vivo crosslinking and MS-based protein correlation profiling [PDF]
We present a methodology using in vivo crosslinking combined with HPLC-MS for the global analysis of endogenous protein complexes by protein correlation profiling. Formaldehyde crosslinked protein complexes were extracted with high yield using denaturing
Andersen +52 more
core +2 more sources

