Results 91 to 100 of about 15,577 (237)

Multicenter, open-label study of the sustained-release formulation of azithromycin (azithromycin SR) for treatment of acute bronchitis and secondary infection of chronic respiratory disease

, 2009
マクロライド系抗菌薬であるazithromycin（AZM）の新剤型，経口懸濁液用の徐放性製剤（単回投与製剤）の急性気管支炎および慢性呼吸器疾患の二次感染患者を対象とした第3相，多施設共同，非盲検非対照試験を実施し，AZM単回投与製剤2 g単回経口投与時の有効性および安全性を検討した。　主要評価項目である臨床効果解析対象集団の第8日目の臨床効果（有効率）は，全体で93.3％（42/45例）であり，疾患別では急性気管支炎が97.0％（32/33例），慢性呼吸器疾患の二次感染が83.3％（10/12例 ...
渡辺, 彰, 二木, 芳人, 青木, 信樹, 河野, 茂   +3 more
core  

Nail Toxicities Associated With Anticancer Therapies in Children

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail toxicities are a frequent yet often underrecognized component of dermatologic adverse events in children receiving anticancer therapies. Both conventional cytotoxic chemotherapy and newer targeted agents can affect the nail matrix, nail bed and periungual tissues, producing a broad spectrum of clinical manifestations that range from ...
Luca Rapparini, Michela Starace
wiley   +1 more source

A case of clinical and microbiological failure of azithromycin therapy in Salmonella enterica serotype Typhi despite low azithromycin MIC

International Journal of Infectious Diseases, 2017
Typhoid fever remains a serious problem in many developing countries. Due to resistance to multiple first line drugs, azithromycin has evolved as an important drug in the treatment of typhoid.
Abi Manesh, Veeraraghavan Balaji, Devanga Ragupathi Naveen Kumar, Priscilla Rupali   +3 more
doaj   +1 more source

Review of nutrition management of pediatric intestinal pseudo‐obstruction

Nutrition in Clinical Practice, EarlyView.
Abstract Chronic intestinal pseudo‐obstruction (CIPO) is a rare, heterogeneous, and debilitating disorder characterized by profound intestinal dysmotility and severe nutrition challenges. Its presentation resembles that of mechanical bowel obstruction, but CIPO occurs in the absence of luminal obstruction.
Senthilkumar Sankararaman, Raisa Rani James, Bushra El‐Amaireh, Andrea Adler, Kadakkal Radhakrishnan, Sujithra Velayuthan   +5 more
wiley   +1 more source

Outcomes associated with azithromycin use among patients hospitalized with non-severe community-acquired pneumonia

Antimicrobial Stewardship & Healthcare Epidemiology
Introduction: Community-acquired pneumonia (CAP) is the leading infectious cause for hospitalization. Guidelines recommend use of a macrolide antibiotic with a beta-lactam for coverage of atypical organisms; however, data supporting macrolide coverage ...
Ashwin Gupta, Emily Walzl, David Ratz, Jennifer Horowitz, Elizabeth McLaughlin, Tejal Gandhi, Lindsay Petty, Anurag Malani, David Paje, Preeti Misra, Scott Kaatz, Steven Bernstein, Mariam Younas, Scott Flanders, Valerie Vaughn   +14 more
doaj   +1 more source

Topical azithromycin or ofloxacin for endophthalmitis

, 2012
Michael W Stewart, Michael L StewartDepartment of Ophthalmology, Mayo Clinic, Jacksonville, FL, USAThe recently published study by Romero-Aroca et al1 raises interesting questions regarding the effect of choice of topical antibiotic (azithromycin versus ...
Stewart MW, Stewart ML
core  

Evidence‐based guideline for clinical practice in the diagnosis, treatment, management, and prevention of recurrent wheezing in infants and toddlers in China

Pediatric Investigation, EarlyView.
ABSTRACT Wheezing is a common respiratory symptom in infants and toddlers, and recurrent wheezing is a significant respiratory disorder affecting this age group. Given the multifactorial etiology of recurrent wheezing, clinical practice lacks standardized diagnostic and therapeutic protocols. Recent years have witnessed substantial progress in clinical
Committee of Pediatrics, China Medical Education Association, Cooperative Group of Asthma, the Subspecialty Group of Respiratory, the Society of Pediatrics, Chinese Medical Association, Pediatric Respiratory Work Committee, Society of Pulmonologists, Chinese Medical Doctor Association, Committee of Pediatrics, Chinese Research Hospital Association, Pediatric Professional Committee of the Chinese Non‐public Medical Institutions Association, Professional Committee of Children's Health and Pharmaceutical Research, China Association of Traditional Chinese Medicine, Children's Safe Medication Branch of China News of Drug Information Association, Pediatric Expert Committee of China Primary Health Care Foundation, China International Medical Foundation   +16 more
wiley   +1 more source

Azithromycin use before and during the COVID- 19 pandemic and the impact of implementing national evidence-based guidelines in Qatar

Clinical Epidemiology and Global Health
Background: Initial small, uncontrolled studies suggested a beneficial effect of azithromycin in individuals with COVID-19. However, subsequent studies have not confirmed its effectiveness. We assessed azithromycin usage before and during the pandemic in
Adeel A. Butt, Sherin Shams, Hanaa Nafady-Hego, Zain Bhutta, Atika Jabeen, Aimon B. Malik, Anil G. Thomas, Samah Saleem, Aftab M. Azad, Muna Almaslamani, Abdullatif Alkhal, Abdul-Badi Abou-Samra   +11 more
doaj   +1 more source

Chiropractic spinal manipulative therapy versus physical therapist‐led exercise and the risk of cauda equina syndrome in adults with lumbar disc herniation, stenosis, or radiculopathy

PM&R, EarlyView.
Abstract Background Cauda equina syndrome is a surgical emergency often caused by lumbar disc herniation. Spinal manipulative therapy is commonly used for lumbar spine disorders, but case reports have raised concerns it may precipitate cauda equina syndrome. One cohort study suggested no increased risk, although it did not focus on patients with lumbar
Robert J. Trager, Anthony N. Baumann, Romeo‐Paolo T. Perfecto, Christine M. Goertz   +3 more
wiley   +1 more source

No increased risk of spinal cerebrospinal fluid leak after spinal manipulative therapy: A retrospective cohort study

PM&R, EarlyView.
Abstract Background Spinal cerebrospinal fluid (CSF) leaks, a rare but debilitating condition, have been described following spinal manipulative therapy (SMT) in case reports. However, the nature of the potential association between SMT and CSF leak is uncertain, and symptoms such as neck pain or headache may reflect preexisting leaks rather than ...
Robert J. Trager, Collin M. Labak, Anthony N. Baumann, Tyler H. Snodgrass, Zachary A. Cupler   +4 more
wiley   +1 more source