Results 91 to 100 of about 63,105 (214)

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Efficacy of Azithromycin and Meropenem in Pediatric XDR Salmonella Typhi: A Retrospective Study from Abbottabad, Pakistan

Journal of the Dow University of Health Sciences
Objective: To evaluate the efficacy of azithromycin as a first-line therapy and the combination of meropenem and azithromycin as the second-line therapy in treating pediatric patients with extensively drug-resistant (XDR) Salmonella Typhi in Abbottabad,
Khyal Muhammad, Kalsoom, Amna Khan, Anis Ur Rehman, Khadija Bibi   +4 more
doaj   +4 more sources

Characterization of azithromycin-resistant Shigella flexneri serotype 2a isolates using whole genome sequencing in Ontario from 2016 to 2018

Microbiology Spectrum
Azithromycin-resistant shigellosis is increasing globally. This retrospective analysis of Shigella flexneri serotype 2a isolates from 2016 to 2018 in Ontario found nearly half were azithromycin (47.7%, 72/151) and ciprofloxacin (50.7%, 77/152) resistant.
Alefiya Neemuchwala, Karen Johnson, Kirby Cronin, Sandra Zittermann, Analyn Peralta, Vanessa G. Allen, Samir N. Patel   +6 more
doaj   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Outcomes of a Routine Screening Protocol to Prevent Metamycoplasma and Ureaplasma Infection in Lung Transplant Recipients

Transplant Infectious Disease, EarlyView.
This study analyzed outcomes of an early Mollicute (Mycoplasma hominis and Ureaplasma spp.) screening protocol using BAL PCR with preemptive treatment and ammonia monitoring in lung transplant recipients. This appears to be a practical and reasonably effective approach for preventing early Mollicute infection and hyperammonemia syndrome.
Lalithaa Thirunavukarasu Murugan, Anika Sasidharan Nair, Marie M. Budev, Maureen Converse, Nabin K. Shrestha, Christine E. Koval   +5 more
wiley   +1 more source

Age‐Related and Seasonal Variation in Malaria and Other Causes of Fever and Their Association With Clinical Outcomes in Southern Angola: A Hospital‐Based Study

Tropical Medicine &International Health, EarlyView.
ABSTRACT Background Acute febrile illnesses in sub‐Saharan Africa are often attributed to malaria, yet many patients test negative for malaria parasites. The aetiology of nonmalarial fevers remains understudied. Here, we examine likely causes of febrile illnesses and their association with poor clinical outcomes in Angola.
Helga E. M. Gonçalves, Maria Lina Antunes, Jorge Seixas, Marcelo U. Ferreira   +3 more
wiley   +1 more source

Prevalence of Antimicrobial Use in Small Animal Dermatology Referral Practices in the United States

Veterinary Dermatology, EarlyView.
ABSTRACT Background Antimicrobial resistance is a critical global health concern driven by antimicrobial use. Dermatological conditions are common reasons for antimicrobial prescriptions in small animal practice, yet data on prescribing patterns in veterinary dermatology referral settings are lacking. Hypothesis/Objectives To characterise the frequency,
Domenico Santoro, Emma R. Bollig, Jennifer L. Granick   +2 more
wiley   +1 more source

A Standards‐Based, Cloud‐Hosted CDS System for Gonorrhea Treatment and HIV Screening

Learning Health Systems, Volume 10, Issue 4, October 2026.
ABSTRACT Objective Neisseria gonorrhoeae (or gonococcus, GC) infections have increased in incidence and antibiotic resistance, prompting updates to management guidelines. Additionally, patients with recent GC infections have been identified as a target population for human immunodeficiency virus (HIV) screening and prevention. With the rapidly changing
Edna Shenvi, Aziz Boxwala, Sarah Shaw, Andre Berro, Saugat Karki, Matthew Pooser, Jane E. Yang, Gema Dumitru, Jeanne Ocampo, Amrita Tailor, Sanjat Kanjilal, Carlos Paredes, Ritche Hao, Nitu Kashyap, David Liebovitz, Alejandro Pérez   +15 more
wiley   +1 more source

The Role of the Gut Microbiota in Allogeneic Hematopoietic Cell Transplantation

American Journal of Hematology, Volume 101, Issue 8, Page 1980-1996, August 2026.
ABSTRACT Allogeneic hematopoietic cell transplantation (allo‐HCT) is an effective treatment for patients with high‐risk hematologic malignancies. Over the last decade, gut microbiota composition during allo‐HCT has been associated with patients' outcomes.
Wenjing Hao, Nicolas Stocker, Béatrice Gaugler, Mohamad Mohty, Florent Malard   +4 more
wiley   +1 more source

Harnessing Repurposed Drugs to Enhance Temozolomide Efficacy in Glioblastoma

Cancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Glioblastoma (GB) is the most aggressive primary malignant brain tumor in adults and remains associated with poor survival despite surgical resection followed by radiotherapy and temozolomide (TMZ) chemotherapy. Intrinsic and acquired resistance to TMZ, including MGMT‐dependent DNA repair and activation of pro‐survival pathways ...
Ali Nakhaei, Atefeh Taghavi, Amir R. Afshari, Farzaneh Davoudi, Elaheh Gheybi, Mohammad Jalili‐Nik   +5 more
wiley   +1 more source