Results 71 to 80 of about 78,921 (263)

Should azithromycin be used to treat COVID-19? A rapid review

BJGP Open, 2020
Background: There are no established effective treatments for COVID-19. While novel drugs are being developed, azithromycin has been identified as a candidate treatment in the interim.
Kome Gbinigie, Kerstin Frie
doaj   +1 more source

Pediatric Use of Off-Label Medicines and Nonevidence-Based Supplements for COVID-19: Findings From the 2015 Pelotas Birth Cohort Study (Brazil). [PDF]

Pharmacoepidemiol Drug Saf
ABSTRACT Purpose Pediatric off‐label medicine use increased during the COVID‐19 pandemic, exposing children to nonevidence‐based treatments. We described the use of nonevidence‐based COVID‐19 medicines and supplements among children from the 2015 Pelotas Birth Cohort, according to sociodemographic and health‐related characteristics.
Bertoldi AD, Guimarães FS, Boing AC, Silveira MPT, Hallal PC, da Silveira MF.   +5 more
europepmc   +2 more sources

Gas chromatography–mass spectrometry analysis and comprehensive evaluation of antibacterial, antioxidant and anti‐inflammatory properties of Thymus capitatus extracts from Libya

JSFA reports, EarlyView.
Abstract Background The emergence of multidrug‐resistant bacteria necessitates the development of alternative therapeutic approaches. Thymus capitatus, a Mediterranean medicinal plant, has been traditionally used to treat various ailments, but its bioactive potential from Libyan origins remains underexplored.
Ahmed Saeed Kabbashi, Taher Issa Shailabi, Ahlam Mohamed Keshar, Amel Mahmoud Abdrabo, Ahmed Ali Mustafa, Bushray Salih Jabullah, Rama Burhan Hasan, Mona Rafea Mosa, Esraa Radwan Ibrahim, Maryam Mohammed Ibrahim   +9 more
wiley   +1 more source

Intermittent preventive treatment of malaria in pregnancy: at the crossroads of public health policy.

, 2011
The intermittent preventive treatment of malaria in pregnancy (IPTp) with sulphadoxine-pyrimethamine (SP) has been a key component of the focused antenatal care package for nearly a decade, reducing the burden of low birthweight attributable to malaria ...
Chandramohan, Daniel, Chico, R Matthew, Daniel Chandramohan, R. Matthew Chico   +3 more
core   +1 more source

Nail Toxicities Associated With Anticancer Therapies in Children

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail toxicities are a frequent yet often underrecognized component of dermatologic adverse events in children receiving anticancer therapies. Both conventional cytotoxic chemotherapy and newer targeted agents can affect the nail matrix, nail bed and periungual tissues, producing a broad spectrum of clinical manifestations that range from ...
Luca Rapparini, Michela Starace
wiley   +1 more source

NKX2‐1 Downstream Regulatory Structural Variants Explain a Substantial Proportion of Molecular Diagnoses in Patients With Benign Hereditary Chorea

Movement Disorders, EarlyView.
Abstract Background NKX2‐1–related disorders (NKX2‐1‐RDs) classically present with a triad of neurological, endocrine, and pulmonary manifestations, including benign hereditary chorea. However, in a fraction of patients, NKX2‐1 coding variants are not detected, and variants outside the NKX2‐1 locus have been reported.
Robin Wijngaard, Lucy Dougherty‐de Miguel, German Demidov, Galuh Astuti, Amaia Lasa‐Aranzasti, Ana Cueto‐González, Marta Correa‐Vela, Carlos Lázaro‐Hernández, Charlotte A. Haaxma, Clara D.M. van Karnebeek, David Gómez‐Andrés, Ignacio Iglesias‐Serrano, Jiddeke M. van de Kamp, Jolanda Schieving, Laura Trujillano, Marc Engelen, Beatriz Muñoz‐Cabello, Roderick P.P.W.M. Maas, Thatjana Gardeitchik, Victoria Gonzalez, Annemarie de Vreugd, Cristina Pérez‐Sanchez, Elisabet Lloveras, Erik‐Jan Kamsteeg, Maartje Pennings, Natalia Rey‐Viñets, Javier Sánchez, Ronald van Beek, Antonio Moreno‐Galdó, Lisenka E.L.M. Vissers, Kornelia Neveling, Anna Marcé‐Grau, Machteld M. Oud, Belén Pérez‐Dueñas   +33 more
wiley   +1 more source

A new plasmid carrying mphA causes prevalence of azithromycin resistance in enterotoxigenic Escherichia coli serogroup O6

BMC Microbiology, 2020
Background At present, azithromycin has become an effective treatment for severe diarrhea caused by Enterotoxigenic Escherichia coli (ETEC) infection. However, enterobacteria have begun to develop resistance to azithromycin and have attracted attention ...
Ying Xiang, Feng Wu, Yinghui Chai, Xuebin Xu, Lang Yang, Sai Tian, Haoran Zhang, Yinxia Li, Chaojie Yang, Hongbo Liu, Shaofu Qiu, Hongbin Song, Yansong Sun   +12 more
doaj   +1 more source

Feasibility of eliminating ocular Chlamydia trachomatis with repeat mass antibiotic treatments. [PDF]

, 2004
CONTEXT: Mass antibiotic administrations for ocular chlamydial infection play a key role in the World Health Organization's trachoma control program. Mathematical models suggest that it is possible to eliminate trachoma locally with repeat mass treatment,
Lee, David Chung, Yi, Elizabeth H, Lietman, Thomas M, Alemayehu, Wondu, Whitcher, John P, Gaynor, Bruce D, Melese, Muluken, Chidambaram, Jaya Devi, Saidel, Michael, Zhou, Zhaoxia, Cevallos, Vicky, Donnellan, Cathy   +11 more
core   +1 more source

Design and baseline data of a randomized trial to evaluate coverage and frequency of mass treatment with azithromycin: the Partnership for Rapid Elimination of Trachoma (PRET) in Tanzania and The Gambia.

, 2011
OBJECTIVES: Trachoma is the principal cause of infectious blindness. As part of its strategy to eliminate trachoma, the World Health Organization recommends annual mass antibiotic treatment for at least 3 years with an 80% population coverage target ...
Stare, Dianne, Emma Harding-Esch, Mabey, David, Harding-Esch, Emma, Munoz, Beatriz, Holland, Martin, Sheila West, Gaydos, Charlotte, Dianne Stare, West, Sheila, Charlotte Gaydos, Bailey, Robin, null null, Beatriz Munoz, David Mabey, Martin Holland, Robin Bailey   +16 more
core   +1 more source

Genome Analysis of Corynebacterium ulcerans Isolates Chronologically Recovered From the Same Cat for Two Years: Circulation in a Cat Shelter

Microbiology and Immunology, EarlyView.
ABSTRACT Toxigenic Corynebacterium ulcerans, a zoonotic pathogen, was isolated repeatedly from a cat in an in‐house group in Japan. Although the cat was cured once by antibiotic treatment, clonal isolates of the original pathogenic strain were recovered repeatedly during a 2‐year course.
Ryoko Jikihara, Miyuki Kimura, Hyun Kim, Tsuyoshi Sekizuka, Masatomo Morita, Makoto Kuroda, Akihiko Yamamoto, Mitsutoshi Senoh, Masaaki Iwaki   +8 more
wiley   +1 more source