Results 61 to 70 of about 15,577 (237)

Upregulation of outer membrane porin gene ompC contributed to enhancement of azithromycin susceptibility in multidrug-resistant Escherichia coli

Microbiology Spectrum
The outer membrane (OM) in gram-negative bacteria contains proteins that regulate the passive or active uptake of small molecules for growth and cell function, as well as mediate the emergence of antibiotic resistance.
Xing-Wei Luo, Peng-Liang Li, Ya-Jun Zhai, Yu-Shan Pan, Gong-Zheng Hu, Dan-Dan He   +5 more
doaj   +1 more source

Synthesis and Glycosidase Inhibition Studies of Novel Exoglycals Targeting GH3 Family Enzymes: Insights from Comparative Analysis with Macrolide Antibiotics

Chemistry – A European Journal, EarlyView.
A series of structurally diverse exoglycals was synthesized using a modified Julia‐olefination approach from sugar‐derived precursors. These glycosidase transition‐state mimics were further diversified via CuAAC chemistry to yield triazole‐conjugated analogues.
Elisa Ospanow, Oscar L. Alferez, David L. Jakeman   +2 more
wiley   +1 more source

Concerns and Considerations Regarding Azithromycin Use by Physicians

Journal of the Pakistan Medical Association
Dear Editor, Azithromycin is a macrolide antibiotic that targets a wide range of bacteria. It inhibits the growth of many Gram-positive and Gram-negative bacteria, as well as other pathogens like Mycoplasma pneumoniae and Mycobacterium avium complex ...
Nimra Razaque Arain
doaj   +1 more source

A new plasmid carrying mphA causes prevalence of azithromycin resistance in enterotoxigenic Escherichia coli serogroup O6

BMC Microbiology, 2020
Background At present, azithromycin has become an effective treatment for severe diarrhea caused by Enterotoxigenic Escherichia coli (ETEC) infection. However, enterobacteria have begun to develop resistance to azithromycin and have attracted attention ...
Ying Xiang, Feng Wu, Yinghui Chai, Xuebin Xu, Lang Yang, Sai Tian, Haoran Zhang, Yinxia Li, Chaojie Yang, Hongbo Liu, Shaofu Qiu, Hongbin Song, Yansong Sun   +12 more
doaj   +1 more source

Tracheal wash culture is not associated with bronchial infection, remodelling or inflammation in horses with asthma

Equine Veterinary Journal, EarlyView.
Abstract Background Antimicrobials are commonly prescribed for the treatment of equine asthma, despite limited evidence supporting their use. Tracheal wash (TW) bacterial culture results are known to influence antimicrobial prescription decisions. Objectives To determine whether a positive TW bacterial culture in horses with asthma is associated with ...
Laurence Leduc, Guillaume St‐Jean, Jean‐Pierre Lavoie   +2 more
wiley   +1 more source

Design and baseline data of a randomized trial to evaluate coverage and frequency of mass treatment with azithromycin: the Partnership for Rapid Elimination of Trachoma (PRET) in Tanzania and The Gambia.

, 2011
OBJECTIVES: Trachoma is the principal cause of infectious blindness. As part of its strategy to eliminate trachoma, the World Health Organization recommends annual mass antibiotic treatment for at least 3 years with an 80% population coverage target ...
Stare, Dianne, Emma Harding-Esch, Mabey, David, Harding-Esch, Emma, Munoz, Beatriz, Holland, Martin, Sheila West, Gaydos, Charlotte, Dianne Stare, West, Sheila, Charlotte Gaydos, Bailey, Robin, null null, Beatriz Munoz, David Mabey, Martin Holland, Robin Bailey   +16 more
core   +1 more source

Feasibility of eliminating ocular Chlamydia trachomatis with repeat mass antibiotic treatments. [PDF]

, 2004
CONTEXT: Mass antibiotic administrations for ocular chlamydial infection play a key role in the World Health Organization's trachoma control program. Mathematical models suggest that it is possible to eliminate trachoma locally with repeat mass treatment,
Lee, David Chung, Yi, Elizabeth H, Lietman, Thomas M, Alemayehu, Wondu, Whitcher, John P, Gaynor, Bruce D, Melese, Muluken, Chidambaram, Jaya Devi, Saidel, Michael, Zhou, Zhaoxia, Cevallos, Vicky, Donnellan, Cathy   +11 more
core   +1 more source

Acceleration of Singlet Oxygen Evolution by Sonopiezoelectric Charge Transfer Over SrTiO3‐TiO2 Heterojunction for Selective Oxidation

Exploration, EarlyView.
A sonopiezo‐triggered singlet oxygen evolution system by S‐scheme SrTiO3‐TiO2 heterojunction was rationally designed to selectively remove electron‐rich pollutants from water. ABSTRACT Sonopiezo‐mediated heterogeneous catalysis is a promising technology for efficient removal of organic pollutants from wastewater. Nevertheless, it is challenging in real
Weiwei Wang, Chun Lu, Xiaoxiao Liu, Wenlong Yang, Jie Zhou, Chenyao Hu, Xin Li, Guangze Nie   +7 more
wiley   +1 more source

Impact of intra-partum azithromycin on carriage of group A streptococcus in the Gambia: a posthoc analysis of a double-blind randomized placebo-controlled trial

BMC Infectious Diseases, 2022
Background Group A Streptococcus (GAS) is a major human pathogen and an important cause of maternal and neonatal sepsis. Asymptomatic bacterial colonization is considered a necessary step towards sepsis. Intra-partum azithromycin may reduce GAS carriage.
Isatou Jagne, Alexander J. Keeley, Abdoulie Bojang, Bully Camara, Edrissa Jallow, Elina Senghore, Claire Oluwalana, Saikou Y. Bah, Claire E. Turner, Abdul Karim Sesay, Umberto D’Alessandro, Christian Bottomley, Thushan I. de Silva, Anna Roca   +13 more
doaj   +1 more source

Prevalence of malaria and sexually transmitted and reproductive tract infections in pregnancy in sub-Saharan Africa: a systematic review. [PDF]

, 2012
CONTEXT: Malaria and sexually transmitted infections/reproductive tract infections (STIs/RTIs) in pregnancy are direct and indirect causes of stillbirth, prematurity, low birth weight, and maternal and neonatal morbidity and mortality.
Mayaud, Philippe, Chandramohan, Daniel, Chico, R Matthew, Ronsmans, Carine, Mabey, David, Ariti, Cono   +5 more
core   +1 more source