Results 41 to 50 of about 63,105 (214)

Azithromycin inhibits the production of MUC5AC in the airway mucosa of patients with bronchiectasis induced by Pseudomonas aeruginosa

Pakistan Journal of Pharmaceutical Sciences, 2021
To explore the clinical benefits of azithromycin in the treatment of Pseudomonas aeruginosa induced bronchiectasis and to evaluate its effect on MUC5AC.
Junhui Wang, Lei Xu, Yanni Lv, Lingfang Sun   +3 more
doaj   +1 more source

Perigraftitis, an independent biologic complication associated with implants placed in grafted bone

Clinical Advances in Periodontics, EarlyView.
Abstract Background Perigraftitis is a recently introduced concept describing biologic complications specifically associated with implants placed in grafted bone. It is characterized by inflammation resulting from bacterial colonization of grafted bone and/or residual graft particulates.
Jonathan H. Do, Charles M. Cobb, John T. Shen   +2 more
wiley   +1 more source

Synthesis and Glycosidase Inhibition Studies of Novel Exoglycals Targeting GH3 Family Enzymes: Insights from Comparative Analysis with Macrolide Antibiotics

Chemistry – A European Journal, EarlyView.
A series of structurally diverse exoglycals was synthesized using a modified Julia‐olefination approach from sugar‐derived precursors. These glycosidase transition‐state mimics were further diversified via CuAAC chemistry to yield triazole‐conjugated analogues.
Elisa Ospanow, Oscar L. Alferez, David L. Jakeman   +2 more
wiley   +1 more source

Treatment of Mycoplasma genitalium. Observations from a Swedish STD clinic. [PDF]

PLoS ONE, 2013
ObjectivesTo evaluate therapy for Mycoplasma genitalium infection with doxycycline or azithromycin 1 g compared to five days of azithromycin (total dose 1.5 g).MethodsA retrospective case study was performed among patients attending the STD-clinic in ...
Carin Anagrius, Britta Loré, Jørgen Skov Jensen   +2 more
doaj   +1 more source

Cenobamate use in super‐refractory status epilepticus: A report of three cases

Epileptic Disorders, EarlyView.
Abstract Objectives Super‐refractory status epilepticus (SRSE) is a neurological emergency with high morbidity and mortality. Cenobamate, a novel antiseizure medication, may be helpful in managing SRSE, but evidence is limited. Methods This retrospective case series reports the use of cenobamate as add‐on therapy in the management of three cases of ...
Marina Romozzi, Juan Luis Alcala‐Zermeno, Antonio Funcis, Federico Tosto, Marta Piccioli, Luigi Francesco Iannone, Riccardo Maviglia, Masahito Katsuki, Yasuhiko Matsumori, Paolo Calabresi, Raffaele Iorio, Catello Vollono   +11 more
wiley   +1 more source

Tracheal wash culture is not associated with bronchial infection, remodelling or inflammation in horses with asthma

Equine Veterinary Journal, EarlyView.
Abstract Background Antimicrobials are commonly prescribed for the treatment of equine asthma, despite limited evidence supporting their use. Tracheal wash (TW) bacterial culture results are known to influence antimicrobial prescription decisions. Objectives To determine whether a positive TW bacterial culture in horses with asthma is associated with ...
Laurence Leduc, Guillaume St‐Jean, Jean‐Pierre Lavoie   +2 more
wiley   +1 more source

Interleukin-10 levels in azithromycin-induced cardiac damage and the protective role of combined selenium and vitamin E treatment

Toxicology Reports
Azithromycin is a broad-spectrum antibiotic commonly used to treat bacterial infections but is associated with adverse cardiac effects, including oxidative damage and myocardial inflammation.
Heba Hussein Rohym, Mohamed S. Hemeda, Almoatazbellah Mahmoud Elsayed, Mayada Saad Farrag, Heba A. Elsayed, Amgad A. Ezzat, Mohamed A. Ibrahim, Mohammed Makloph   +7 more
doaj   +1 more source

Azithromycin susceptibility testing of Salmonella enterica serovar Typhi: Impact on management of enteric fever

Clinical Infection in Practice, 2021
Background: Drug-resistant enteric fever is increasingly common in the Indian subcontinent. Correctly determining azithromycin resistance matters where drug-resistant enteric fever is common and oral therapy necessary.
Jordan P. Skittrall, David Levy, Christian Obichukwu, Amy Gentle, Marie A. Chattaway, David Hayns, Clare Etheridge, Christopher M. Parry, Vanessa Wong, James Whitehorn   +9 more
doaj   +1 more source

Genomic Insights Into Spatiotemporal Dynamics of Acquired Azithromycin Resistance Genes in Salmonella Strains Worldwide

Food Safety and Health, EarlyView.
ABSTRACT Azithromycin has been used for clinical invasive infections caused by fluoroquinolone‐ and third‐generation cephalosporin‐resistant Salmonella, and mass drug administration with azithromycin has been used to reduce under‐5 mortality in children in some countries.
Yuhang Pei, Mengqi Qu, Ziru Yang, Xuebin Xu, Yanan Wang   +4 more
wiley   +1 more source

Upregulation of outer membrane porin gene ompC contributed to enhancement of azithromycin susceptibility in multidrug-resistant Escherichia coli

Microbiology Spectrum
The outer membrane (OM) in gram-negative bacteria contains proteins that regulate the passive or active uptake of small molecules for growth and cell function, as well as mediate the emergence of antibiotic resistance.
Xing-Wei Luo, Peng-Liang Li, Ya-Jun Zhai, Yu-Shan Pan, Gong-Zheng Hu, Dan-Dan He   +5 more
doaj   +1 more source