Results 21 to 30 of about 63,105 (214)

Mass drug administration of antibacterials: weighing the evidence regarding benefits and risks

Infectious Diseases of Poverty, 2022
Background Mass drug administration (MDA) is a strategy to improve health at the population level through widespread delivery of medicine in a community.
Robert J. Rolfe, Hassaan Shaikh, L. Gayani Tillekeratne   +2 more
doaj   +1 more source

In vitro efficacy of 21 dual antimicrobial combinations comprising novel and currently recommended combinations for treatment of drug resistant gonorrhoea in future era. [PDF]

PLoS ONE, 2018
Recent WHO guidelines recommend dual therapy with ceftriaxone or cefixime plus azithromycin for gonorrhea. Azithromycin in combination with gentamicin or spectinomycin has been recommended in treatment failure cases.
Vikram Singh, Manju Bala, Aradhana Bhargava, Monika Kakran, Ravi Bhatnagar   +4 more
doaj   +1 more source

Azithromycin (Zithromax ^®) [PDF]

Infectious Diseases in Obstetrics and Gynecology, 1996
Azithromycin (Zithromax ®, Pfizer, Inc., New York, NY) is a 15‐membered‐ring macrolide and the first azalide antibiotic. It is distinguished from other macrolides by its rapid and extensive penetration into intracellular and interstitial tissue compartments, accompanied by prolonged tissue and serum half‐lives.
openaire   +2 more sources

Minimum inhibitory concentrations of azithromycin in clinical isolates of Mycobacterium avium complex in Japan

Microbiology Spectrum
The latest guidelines include azithromycin as a preferred regimen for treating Mycobacterium avium complex (MAC) pulmonary disease. However, serially collected susceptibility data on clinical MAC isolates are limited, and no breakpoints have been ...
Yoshifumi Uwamino, Wataru Aoki, Rika Inose, Yuka Kamoshita, Kei Mikita, Ho Namkoong, Tomoyasu Nishimura, Hiromichi Matsushita, Naoki Hasegawa   +8 more
doaj   +1 more source

Effect of azithromycin-conjugated gold and silver nanoparticles on the cytotoxicity of hepatocellular cancer cells

Pakistan Journal of Pharmaceutical Sciences
Azithromycin is a member of macrolide antibiotics, and has been reported to inhibit the proliferation of cancer cells. Nanoparticles particularly nanometals have been recently investigated in cancer chemotherapy owing to their enhanced pharmacokinetic ...
Dabeeran Zehra, Shumaila Usman, Almas Jabeen, Kauser Ismail, Zahida Memon, Zara Aslam, Muhammad Raza Shah   +6 more
doaj   +1 more source

Creation of an assessment system for measuring the bitterness of azithromycin-containing reverse micelles

Asian Journal of Pharmaceutical Sciences, 2018
We aimed to develop a novel method for assessing the bitterness of azithromycin-containing reverse micelles (AM-containing RMs). Azithromycin-containing reverse micelles were prepared by processing Lipoid E80 and medium chain triglycerides via a freeze ...
Ri Huang, Yadan Zhang, Tao Wang, Liao Shen, Zhen Zhang, Yang Wang, Dongqin Quan   +6 more
doaj   +1 more source

Safety of azithromycin in infants under six months of age in Niger: A community randomized trial. [PDF]

PLoS Neglected Tropical Diseases, 2018
BACKGROUND:Mass azithromycin distribution reduces under-5 child mortality. Trachoma control programs currently treat infants aged 6 months and older. Here, we report findings from an infant adverse event survey in 1-5 month olds who received azithromycin
Catherine E Oldenburg, Ahmed M Arzika, Ramatou Maliki, Mohamed Salissou Kane, Elodie Lebas, Kathryn J Ray, Catherine Cook, Sun Y Cotter, Zhaoxia Zhou, Sheila K West, Robin Bailey, Travis C Porco, Jeremy D Keenan, Thomas M Lietman, MORDOR Study Group   +14 more
doaj   +1 more source

Azithromycin Prevents Pregnancy Loss: Reducing the Level of Tumor Necrosis Factor-Alpha and Raising the Level of Interleukin-10 in Rats

Mediators of Inflammation, 2013
The aim of this study was to determine the effect of azithromycin on LPS-induced pregnancy loss. Thirty-six pregnant female Wistar rats were divided into 4 equal groups as follows: control group, where 0.3 mL of normal saline solution was administered ...
Ayse Er
doaj   +1 more source

Age‐associated immune dysregulation links to disease severity in macrolide‐resistant Mycoplasma pneumoniae pneumonia: Insights from a comparative juvenile–adult mouse model

Animal Models and Experimental Medicine, EarlyView.
Macrolide‐resistant Mycoplasma pneumoniae (MRMP) infected both juvenile and adult mice, with results compared to normal juvenile mice. The findings revealed comparable bacterial loads between juvenile and adult mice, yet juvenile mice exhibited more severe lung damage and elevated levels of inflammatory cytokines.
Xuejun Li, Yudong Wang, Liyong Liu, Mengmeng Gong, Jinlong Wang, Yuqing Cao, Zhixin Sun, Fanliang Meng, Qiuyan Wang, Hongji Wu, Fei Zhao, Yan Ma, Yibai Xiong   +12 more
wiley   +1 more source

Nanomotion technology for testing azithromycin susceptibility of Salmonella enterica

Microbiology Spectrum
Invasive salmonellosis caused by Salmonella enterica subspecies affects millions of people every year, mostly children from low-income countries, and is associated with a high mortality rate. Azithromycin is used to treat invasive salmonellosis resistant
Mariliis Hinnu, Toomas Mets, Ivana Kerkez, Marta Putrinš, Niilo Kaldalu, Gino Cathomen, Marta Pla Verge, Danuta Cichocka, Alexander Sturm, Tanel Tenson   +9 more
doaj   +1 more source