Results 11 to 20 of about 80,970 (245)

Impact of prophylactic oral azithromycin during labor on Azithromycin Resistance (AMR) in nasal Staphylococcus aureus and Streptococcus pneumoniae in women and infants in the multi-country Azithromycin Prevention in Labor Use Study (A-PLUS).

PLoS ONE
BackgroundProphylactic oral azithromycin vs. placebo reduced maternal, but not neonatal, mortality/sepsis in the A-PLUS Randomized Trial. While prophylactic intrapartum azithromycin reduces maternal mortality/sepsis, it may promote antimicrobial ...
Patricia L Hibberd, Jean H Kim, Marissa Trotta, Sixto M Leal, Anna Aceituno, Doyle V Ward, Archana Patel, Akila Subramaniam, Waldemar A Carlo, Imran Ahmed, Sarah Saleem, Sk Masum Billah, Rashidun Haque, Manolo Mazariegos, Fabian Esamai, Manjunath S Somannavar, Shivaprasad S Goudar, Elwyn Chomba, Muska Mwenchanya, Adrien Lokangaka, Antoinette Tshefu, Robert L Goldenberg, Melissa Bauserman, Nancy F Krebs, Sherri Bucher, Richard J Derman, William A Petri, Marion Koso-Thomas, Denise C Babineau, Elizabeth M McClure, Alan T N Tita   +30 more
doaj   +2 more sources

The use of Azithromycin and Hydroxychloroquine in the Treatment of Covid-19 [PDF]

SHS Web of Conferences, 2023
This paper mainly studies the therapeutic effect of azithromycin and hydroxychloroquine on COVID-19. Severe acute respiratory syndrome is one of the key clinical manifestations of COVID-19, and azithromycin is considered to be a feasible treatment.
Ma Yue, Lu Jiawei, Qin Si
doaj   +1 more source

Dry Powder Formulation of Azithromycin for COVID-19 Therapeutics [PDF]

, 2023
Aim: The aim of this study is to develop dry powder formulations of azithromycin-loaded poly(lactic-co-glycolic acid) (PLGA) nanocomposite microparticles for pulmonary delivery to improve the low bioavailability of azithromycin.
Somavarapu, Satyanarayana, Zariwala, Mohammed Gulrez, Chan, Stefanie Ho Yi, Sheikh, Khalid, Zariwala, M., Chan, S.H.Y., Sheikh, K., Somavarapu, S.   +7 more
core   +1 more source

Azithromycin and the microbiota of cystic fibrosis sputum

BMC Microbiology, 2021
Background Azithromycin is commonly prescribed drug for individuals with cystic fibrosis (CF), with demonstrated benefits in reducing lung function decline, exacerbation occurrence and improving nutrition.
Nicole Acosta, Christina S. Thornton, Michael G. Surette, Ranjani Somayaji, Laura Rossi, Harvey R. Rabin, Michael D. Parkins   +6 more
doaj   +1 more source

Sustained Transmission of Neisseria gonorrhoeae Strains with High-Level Azithromycin Resistance (MIC ≥ 256 μg/mL) in Argentina, 2018 to 2022

Microbiology Spectrum, 2023
Azithromycin combined with ceftriaxone is the recommended dual therapy for uncomplicated gonorrhea in many countries. Nevertheless, the increasing prevalence of azithromycin resistance compromises the effectiveness of this treatment strategy.
Ricardo Ariel Gianecini, Tomas Poklepovich, Daniel Golparian, Noelia Cuenca, Laura Scocozza, Silvina Bergese, Liliana Fernández Canigia, Viviana Vilches, María Julia Lazzarino Elgart, Magnus Unemo, Josefina Campos, Patricia Galarza   +11 more
doaj   +1 more source

The timing of azithromycin treatment is not associated with the clinical prognosis of childhood Mycoplasma pneumoniae pneumonia in high macrolide-resistant prevalence settings. [PDF]

PLoS ONE, 2018
Mycoplasma pneumoniae infection is a major cause of community-acquired pneumonia in children. We performed a retrospective study to evaluate the clinical impact of the timing of azithromycin treatment in children with Mycoplasma pneumoniae pneumonia in ...
Dehua Yang, Linghong Chen, Zhimin Chen
doaj   +1 more source

Baicalin acts as an adjuvant to potentiate the activity of azithromycin against Staphylococcus saprophyticus biofilm: an in vitro, in vivo, and molecular study

Veterinary Research, 2022
Staphylococcus saprophyticus is frequently involved in various difficult-to-treat infections due to the formation of biofilms. To identify useful antibiofilm strategies, this study explored the efficacy and mechanism of baicalin in enhancing the ability ...
Jinli Wang, Siya Li, Jinwu Meng, Jinyue Zhu, Tianxin Qiu, Wenjia Wang, Jinxue Ding, Zhenguang Liu, Kun Li, Mujahid lqbal, Deyun Wang, Yi Wu, Jiaguo Liu   +12 more
doaj   +1 more source

Azithromycin Reduction to Reach Elimination of Trachoma (ARRET): study protocol for a cluster randomized trial of stopping mass azithromycin distribution for trachoma

BMC Ophthalmology, 2021
Background The World Health Organization (WHO) recommends annual mass azithromycin distribution until districts drop below 5% prevalence of trachomatous inflammation—follicular (TF).
Abdou Amza, Boubacar Kadri, Beido Nassirou, Ahmed M. Arzika, Ariana Austin, Fanice Nyatigo, Elodie Lebas, Benjamin F. Arnold, Thomas M. Lietman, Catherine E. Oldenburg   +9 more
doaj   +1 more source

Formulation and Evaluation of Azithromycin Dihydrate Solid Dispersion with Esther of Polyethylene Glycol-6000 and Stearic Acid Using A Co-Grinding Technique

Science and Technology Indonesia, 2023
Azithromycin is a narrow-spectrum bacterial growth inhibitory antibiotic derived from macrolides with low dissolution in water. Several methods have been carried out to increase the dissolution of medicinal substances, one of which is solid dispersion ...
Mardiyanto, Budi Untari, Ady Mara, Nauval Hady Prasetyo   +3 more
doaj   +3 more sources

EFFICACY OF AZITHROMYCIN ON EXPERIMENTAL TOXOPLASMOSIS INFECTED MICE [PDF]

Journal of the Egyptian Society of Parasitology, 2020
Toxoplasma gondii is an opportunistic protozoan that causes a devastating disease in immunocompromisedindividuals and congenitally infected neonates or children.
GEHAN A. RASHED, SAFAA H. YOUSSIF, ASHRAF M. A. BARAKAT, GHADA H. OMAR, NAGWA S. M. ALY, ATEF H. ABD EL HAMID, MONA E. NASR, KAWKAB A. AHMED   +7 more
doaj   +1 more source