Results 51 to 60 of about 15,577 (237)

Ocrelizumab‐induced colitis: VigiBase disproportionality analysis, case reports and literature review

British Journal of Clinical Pharmacology, EarlyView.
Aims Ocrelizumab is a humanized anti‐CD20 monoclonal antibody used in multiple sclerosis. Since its commercialization, several cases of ocrelizumab‐induced colitis have been reported in the scientific literature. Methods To explore the potential association of ocrelizumab with colitis as an adverse drug reaction (ADR), we conducted a descriptive and ...
Audrey Fresse, Christophe Hommel, Nadine Petitpain, Philippe Kerschen   +3 more
wiley   +1 more source

Interleukin-10 levels in azithromycin-induced cardiac damage and the protective role of combined selenium and vitamin E treatment

Toxicology Reports
Azithromycin is a broad-spectrum antibiotic commonly used to treat bacterial infections but is associated with adverse cardiac effects, including oxidative damage and myocardial inflammation.
Heba Hussein Rohym, Mohamed S. Hemeda, Almoatazbellah Mahmoud Elsayed, Mayada Saad Farrag, Heba A. Elsayed, Amgad A. Ezzat, Mohamed A. Ibrahim, Mohammed Makloph   +7 more
doaj   +1 more source

Early clinical pharmacology evaluation of the novel anti‐inflammatory macrolide, glasmacinal (EP395): tolerability, pharmacokinetics and drug interactions

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims This work assessed the pharmacokinetics (PK), safety and tolerability of glasmacinal (EP395, an oral anti‐inflammatory macrolide with negligible antimicrobial activity in development for COPD treatment) in two healthy participant trials: ‘first‐in‐human’ (FIH) and ‘drug–drug‐interaction’ (DDI).
Dave Singh, Kate Hanrott, Olof Breuer, Johan Bylund, Björn Schultze, Virginia Norris   +5 more
wiley   +1 more source

Sub-MICs of Azithromycin Decrease Biofilm Formation of S. suis and Increase Capsular Polysaccharide Content of S. suis

Frontiers in Microbiology, 2016
S. suis (Streptococcus suis) caused serious disease symptoms in humans and pigs. S. suis is able to form thick biofilms and this increases the difficulty of treatment.
Yanbei Yang, Jianqing Chen, Yulin Zhao, Jing-Wen Bai, Wen-Ya Ding, Yonghui Zhou, Xue-Ying Chen, Di Liu, YanHua Li   +8 more
doaj   +1 more source

Should azithromycin be used to treat COVID-19? A rapid review

BJGP Open, 2020
Background: There are no established effective treatments for COVID-19. While novel drugs are being developed, azithromycin has been identified as a candidate treatment in the interim.
Kome Gbinigie, Kerstin Frie
doaj   +1 more source

Azithromycin susceptibility testing of Salmonella enterica serovar Typhi: Impact on management of enteric fever

Clinical Infection in Practice, 2021
Background: Drug-resistant enteric fever is increasingly common in the Indian subcontinent. Correctly determining azithromycin resistance matters where drug-resistant enteric fever is common and oral therapy necessary.
Jordan P. Skittrall, David Levy, Christian Obichukwu, Amy Gentle, Marie A. Chattaway, David Hayns, Clare Etheridge, Christopher M. Parry, Vanessa Wong, James Whitehorn   +9 more
doaj   +1 more source

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source

Intermittent preventive treatment of malaria in pregnancy: at the crossroads of public health policy.

, 2011
The intermittent preventive treatment of malaria in pregnancy (IPTp) with sulphadoxine-pyrimethamine (SP) has been a key component of the focused antenatal care package for nearly a decade, reducing the burden of low birthweight attributable to malaria ...
Chandramohan, Daniel, Chico, R Matthew, Daniel Chandramohan, R. Matthew Chico   +3 more
core   +1 more source

Root coverage using a microsurfaced acellular dermal matrix: A retrospective case series

Clinical Advances in Periodontics, EarlyView.
Abstract Background Acellular dermal matrices (ADMs) have been used for root coverage for over 25 years, yet few advancements have improved clinical outcomes or reduced complications. This case series evaluated the use of a novel microsurfaced ADM (mADM), which features a microtextured surface designed intended to promote healing and improve graft ...
Yu‐Chang Wu, Guo‐Liang Cheng, Shaun Rotenberg   +2 more
wiley   +1 more source

Perigraftitis, an independent biologic complication associated with implants placed in grafted bone

Clinical Advances in Periodontics, EarlyView.
Abstract Background Perigraftitis is a recently introduced concept describing biologic complications specifically associated with implants placed in grafted bone. It is characterized by inflammation resulting from bacterial colonization of grafted bone and/or residual graft particulates.
Jonathan H. Do, Charles M. Cobb, John T. Shen   +2 more
wiley   +1 more source