Results 21 to 30 of about 96,342 (294)

Mechanism of action, resistance, synergism, and clinical implications of azithromycin

Journal of clinical laboratory analysis (Print), 2022
Azithromycin (AZM), sold under the name Zithromax, is classified as a macrolide. It has many benefits due to its immunomodulatory, anti‐inflammatory, and antibacterial effects.
Mohsen Heidary, Ahmad Ebrahimi Samangani, Abolfazl Kargari, Aliakbar Kiani Nejad, Ilya Yashmi, Moloudsadat Motahar, E. Taki, S. Khoshnood   +7 more
semanticscholar   +1 more source

A Conjugative IncI1 Plasmid Carrying erm(B) and blaCTX-M-104 That Mediates Resistance to Azithromycin and Cephalosporins

Microbiology Spectrum, 2021
In this study, an IncI1 plasmid encoding resistance to both cefotaxime and azithromycin was recovered from a clinical Klebsiella pneumoniae strain. The azithromycin resistance was confirmed to be mediated by the erm(B) gene. This plasmid could be readily
Xuemei Yang, Xiaoxuan Liu, Chen Yang, Edward Wai-Chi Chan, Rong Zhang, Sheng Chen   +5 more
doaj   +1 more source

Effect of Oral Azithromycin vs Placebo on COVID-19 Symptoms in Outpatients With SARS-CoV-2 Infection: A Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2021
Importance Azithromycin has been hypothesized to have activity against SARS-CoV-2. Objective To determine whether oral azithromycin in outpatients with SARS-CoV-2 infection leads to absence of self-reported COVID-19 symptoms at day 14.
C. Oldenburg, B. Pinsky, Jessica M. Brogdon, Cindi Chen, Kevin Ruder, Lina Zhong, Fanice Nyatigo, Catherine A. Cook, Armin Hinterwirth, E. Lebas, Travis K. Redd, T. Porco, T. Lietman, B. Arnold, T. Doan   +14 more
semanticscholar   +1 more source

Evaluation of Effect of Azithromycin on The Heart of Adult Male Albino Rats and The Possible Protective role of VIT.C (Histological and Immune-histochemical Study)

SVU - International Journal of Medical Sciences, 2022
Background: Azithromycin is one of the most common drugs used in the protocol of treatment of pneumonia caused by COVID-19. But many researchers approved its toxicity on heart tissue.
Abeer F. Abd El-Naeem , Azza M.A. Abouelella, Asmaa S. Baset *   +2 more
doaj   +1 more source

Longitudinal evaluation of azithromycin and cytokine concentrations in amniotic fluid following one‐time oral dosing in pregnancy

Clinical and Translational Science, 2021
To utilize noninvasive collection of amniotic fluid in the setting of preterm premature rupture of membranes (PPROMs) to report the time concentration profile of azithromycin in amniotic fluid over 7 days from a single dose, and evaluate the correlation ...
Rupsa C. Boelig, Edwin Lam, Ankit Rochani, Gagan Kaushal, Amanda Roman, Walter K. Kraft   +5 more
doaj   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Synthesis of CoFe2O4 magnetic nanoparticles for application in photocatalytic removal of azithromycin from wastewater

Scientific Reports, 2022
Azithromycin is one of the most widely used antibiotics in medicine prescribed for various infectious diseases such as COVID-19. A significant amount of this drug is always disposed of in hospital effluents.
Ali Modabberasl, T. Pirhoushyaran, S. H. Esmaeili-Faraj   +2 more
semanticscholar   +1 more source

Azithromycin (Zithromax ^®) [PDF]

Infectious Diseases in Obstetrics and Gynecology, 1996
Azithromycin (Zithromax ®, Pfizer, Inc., New York, NY) is a 15‐membered‐ring macrolide and the first azalide antibiotic. It is distinguished from other macrolides by its rapid and extensive penetration into intracellular and interstitial tissue compartments, accompanied by prolonged tissue and serum half‐lives.
openaire   +2 more sources

Assessment of QT Intervals in a Case Series of Patients With Coronavirus Disease 2019 (COVID-19) Infection Treated With Hydroxychloroquine Alone or in Combination With Azithromycin in an Intensive Care Unit.

JAMA cardiology, 2020
This case series assesses QT intervals for French patients with coronavirus disease 2019 (COVID-19) treated with hydroxychloroquine alone or in combination with azithromycin.
Francis Bessière, Hugo Roccia, A. Delinière, Rome Charrière, P. Chevalier, L. Argaud, M. Cour   +6 more
semanticscholar   +1 more source

Azithromycin in the treatment of COVID-19: a review

Expert Review of Anti-Infective Therapy, 2020
Introduction SARS-CoV-2 is a novel virus that causes coronavirus disease-19 (COVID-19). Antiviral and immunomodulatory agents have been proposed as potential treatments. Azithromycin exhibits both properties and therefore may play a role.
D. Echeverría-Esnal, C. Martín-Ontiyuelo, M. E. Navarrete-Rouco, Marta De-Antonio Cuscó, O. Ferrández, J. Horcajada, S. Grau   +6 more
semanticscholar   +1 more source