Results 101 to 110 of about 1,612,284 (282)

Dosing PPARγ Activation With Light Using Fast Relaxing Photoswitches

Angewandte Chemie International Edition, EarlyView.
To achieve spatiotemporal control over PPARγ activity, we designed the fast‐relaxing photoswitchable agonist 6 that selectively activates PPARγ in its light‐induced Z‐state and relaxes within seconds (t1/2 47 s) to the inactive E‐state. This unique profile allowed light‐dosed receptor activation in in vitro settings, enabling biological studies on ...
Loris Knümann, Alba Rodriguez‐Paniagua, Martin Reynders, Silke Duensing‐Kropp, Oliver Thorn‐Seshold, Vasily Morozov, Julian A. Marschner, Daniel Merk   +7 more
wiley   +1 more source

Formal [3 + 2] Cycloaddition of α-Imino Esters with Azo Compounds: Facile Construction of Pentasubstituted 1,2,4-Triazoline Skeletons. [PDF]

Molecules, 2023
Yoshida Y, Ida H, Mino T, Sakamoto M.
europepmc   +1 more source

In Silico to In Cerebro—Development of the Orexin Receptor Antagonist “Photorexant” for Photomodulation In Vitro and in Mouse Brains

Angewandte Chemie International Edition, EarlyView.
Following a structure‐based design approach, photoswitchable derivatives of the FDA‐approved drug suvorexant were designed, docked, synthesized, and characterized pharmacologically at the orexin 1 and 2 receptors (OX1R and OX2R). Optimized “photorexant” showed up to an 11‐fold difference in IC50 between photoisomers, enabled dynamic and reversible ...
Marcus Angermann, Marie H. Deventer, Vicente Ledesma‐Martin, Nuno Martinho, Alix Flake, Silvia Mori, Angel Nuñez, Jaime Pignatelli, Rita C. Guedes, Christophe P. Stove, Michael Decker   +10 more
wiley   +1 more source

MEDICINAL INTEREST OF AZO-BASED ORGANIC COMPOUNDS: A REVIEW [PDF]

, 2016
The azo derived products are versatile building blocker organic compounds used in drug research. In this review, we include the synthetic strategyand medicinal utility of some new azo derived candidates in recent years, which must be a good source of ...
Sahoo, Jyotirmaya, Paidesetty, Sudhir Kumar   +1 more
core   +1 more source

Green Synthesis of Hollow Structures through the Decomposition of Azo Compounds Incorporated inside Polystyrene Particles. [PDF]

ACS Omega, 2022
Yamamoto T, Tsutsumi K, Maeda S.
europepmc   +1 more source

Plasma–Kinetic Coupling and Redox Mechanisms in the Degradation of Acid Red 51 by Atmospheric Corona Discharge

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This study investigates the degradation of the xanthene dye Acid Red 51 (ARE‐51) using atmospheric‐pressure corona discharge plasma, integrating electrical characterization, optical emission spectroscopy (OES), kinetic modeling, and physicochemical analysis to establish a unified plasma–liquid interaction framework. A degradation efficiency of
Cristian Mendoza Benítez, Horacio Martínez Valencia, María del Pilar Rodríguez‐Rojas, Pedro Guillermo Reyes Romero, Aaron Gómez Díaz, Josefina Vergara Sánchez, Dalila Martínez Molina, Fermín Castillo Mejía   +7 more
wiley   +1 more source

Preparation of MOEAMCl and MAAm Based Hydrogels and Effective Use in Anionic Dye Adsorption

Journal of Applied Polymer Science, Volume 142, Issue 16, April 20, 2025.
ABSTRACT In this study, hydrogels based on [2‐(Methacryloyloxy)ethyl]trimethylammonium chloride (MOEAMCl) and methacrylamide (MAAm) were synthesized for the removal of anionic dyes from aqueous solutions. Following detailed characterization, the use of hydrogels for methyl orange (MO) adsorption was investigated.
Hilal Nur Duykop Demir, Ali Delibaş, Ayşe Benk, Ramazan Coşkun   +3 more
wiley   +1 more source

Facile synthesis of azo compounds from aromatic nitro compounds using magnesium and triethylammonium formate

, 2004
Magnesium/triethylammonium formate is a convenient reagent for the reduction of aromatic nitro compounds to corresponding symmetrically substituted azo compounds.
Abiraj, K., Chenne Gowda, D., Srinivasa, G. R.   +2 more
core   +1 more source

Fundamentals, Advances, and Applications of Electrospun Nanofibrous 3D Materials

Journal of Applied Polymer Science, EarlyView.
Three‐dimensional electrospun nanofibrous systems offer unique properties and microenvironments. These properties are determined by the fabrication strategies employed and can be adjusted by the incorporation of functional additives to achieve multifunctionality for specific applications. The applications range from the biomedical to the environmental,
Rebecca Hengsbach, Viraj P. Nirwan, Altangerel Amarjargal, Zahra Asefi, Amir Fahmi   +4 more
wiley   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source