Results 111 to 120 of about 30,490 (251)

Structural Mechanism of an Efficacy Photoswitch Targeting the β2‐adrenergic Receptor

Angewandte Chemie International Edition, EarlyView.
Time‐resolved structures from x‐ray free‐electron laser measurements combined with cellular assays demonstrate how the photoswitchable β‐blocker photoazolol‐1 acts as an efficacy switch of β2‐adrenergic receptor function. Light‐induced ligand repositioning shifts activity from inverse agonism toward neutral antagonism by altering local helical ...
Robin Stipp, Quentin Bertrand, Matilde Trabuco, Anna Duran‐Corbera, Maria Tindara Ignazzitto, Hannah Glover, Fabienne Stierli, Juanlo Catena, Melissa Carrillo, Sina Hartmann, Hans‐Peter Seidel, Matthias Mulder, Thomas Mason, Yasushi Kondo, Maximillian Wranik, Martin Appleby, Christoph Sager, Raymond Sierra, Gregory Gate, Pamela Schleissner, Xinxin Cheng, Tobias Weinert, Robert Cheng, Sandra Mous, John H. Beale, Michal Kepa, Amadeu Llebaria, Michael Hennig, Xavier Rovira, Joerg Standfuss   +29 more
wiley   +1 more source

Synthesis and testing of the first azobenzene mannobioside as photoswitchable ligand for the bacterial lectin FimH

Beilstein Journal of Organic Chemistry, 2013
In order to allow spatial and temporal control of carbohydrate-specific bacterial adhesion, it has become our goal to synthesise azobenzene mannosides as photoswitchable inhibitors of type 1 fimbriae-mediated adhesion of E. coli.
Vijayanand Chandrasekaran, Katharina Kolbe, Femke Beiroth, Thisbe K. Lindhorst   +3 more
doaj   +1 more source

Photoplastic effects in chalcogenide glasses: A review

, 2009
A synopsis of the various photoinduced changes of rheological, mechanical and elastic properties is presented in the first part of the article. After a critical appraisal of a large body of experimental data it suggested that the photoviscous effect ...
Asahara, Berkes, Borisova, Busse, Carlsson, Carlsson, Deryagin, Emelianova, Fritzsche, Fritzsche, Gerasimov, Goryuonova, Grenet, Gump, Hari, Hisakuni, Igo, Ihm, Ikeda, Ikeda, Kastrissios, Kastrissios, Kastrissios, Kastrissios, Kolobov, Kolomiets, Kolomiets, Kolomiets, Koseki, Koseki, Krecmer, Kruglov, Kryshenik, Kuczynski, Kyriazis, Küsters, Larmagnac, Manika, Manika, Matsuda, Matsuda, Natansohn, Natansohn, Nemilov, Osipyan, Osipyan, Ossipyan, Ovshinsky, Poborschii, Repka, Rykov, Salminia, Shimakawa, Shimakawa, Tagantsev, Tagantsev, Tagantsev, Tanaka, Tanaka, Tanaka, Trunov, Trunov, Trunov, Trunov, Trunov, Trunov, Trunov, Trunov, Vonwiller, Wolf, Wolf, Yannopoulos, Yannopoulos, Yu, Ziman   +74 more
core   +1 more source

The Nonadiabatic Nature of the Substituent Effects in Azobenzene

Angewandte Chemie International Edition, EarlyView.
Unified nonadiabatic switching: thermal Z→E isomerization of para‐substituted azobenzenes proceeds through a single nonadiabatic rotational pathway. The iconic bell‐shaped Hammett plot is a σp artifact, not a reflection of a mechanistic change, exposing the limits of single‐reference density functional theory (DFT) and establishing activation entropy ...
Jacob Jan van der Wal, Roman Yu. Peshkov, Jorn D. Steen, Nadja A. Simeth, Stefano Crespi   +4 more
wiley   +1 more source

From nanoscopic to macroscopic photo-driven motion in azobenzene-containing materials

Nanophotonics, 2018
The illumination of azobenzene molecules with UV/visible light efficiently converts the molecules between trans and cis isomerization states. Isomerization is accompanied by a large photo-induced molecular motion, which is able to significantly affect ...
Oscurato Stefano L., Salvatore Marcella, Maddalena Pasqualino, Ambrosio Antonio   +3 more
doaj   +1 more source

Photomechanical Azobenzene Crystals

Nihon Kessho Gakkaishi, 2010
Molecular machines based on the conversion of changes in molecular geometry to mechanical motion in macroscale materials are interesting from the perspective of basic research and offer a wide range of potential applications. Such machines are amenable to remote operation with external stimuli such a photon impingement and do not require direct contact.
openaire   +2 more sources

Affinity Peptides With pH Sensitivity for the Enrichment of CD38+ Cells

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The selective enrichment of cell populations based on surface markers is critical for the advancement of gene and cell therapies. Current antibody‐based cell isolation methods, such as fluorescence‐ and magnetic‐activated cell sorting (FACS and MACS), offer high specificity but are limited by scalability, cost, and potential adverse effects on
Gabrielle Rusch, Mickael Meyer, I. Mohamed Irfan, Carson Huber, Joseph Burclaff, Scott T. Magness, Stefano Menegatti, Michael Daniele   +7 more
wiley   +1 more source

Strategies to control humidity sensitivity of azobenzene isomerisation kinetics in polymer thin films

Communications Materials
Azobenzenes are versatile photoswitches that garner interest in applications ranging from photobiology to energy storage. Despite their great potential, transforming azobenzene-based discoveries and proof-of-concept demonstrations from the lab to the ...
Sami Vesamäki, Henning Meteling, Roshan Nasare, Antti Siiskonen, Jani Patrakka, Nelmary Roas-Escalona, Markus Linder, Matti Virkki, Arri Priimagi   +8 more
doaj   +1 more source

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

BMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo, Nan Li, Daiwei Zhang, Jingya Gu, Zhihuan Liao, Zihao Teng, Xiangfu Du, Peter S. Timashev, Shipeng Chen, Shuaidong Huo   +9 more
wiley   +1 more source

Supramolecular azobenzene polyurethanes

Materiali in tehnologije, 2006
Z diferenčno dinamično kalorimetrijo (DSC), polarizacijsko optično mikroskopijo (POM) in rentgensko difrakcijo (XRD) smo raziskali lastnosti supramolekularnih poliuretanov z azobenzenskimi skupinami, ki smo jih pripravili z molekularnim razpoznavanjem komplementarnih piridinskih skupin v glavni ali stranski verigi poliuretanov (PUPyA, PUPyB) in ...
Ambrožić, Gabriela, Žigon, Majda
openaire   +2 more sources