Results 91 to 100 of about 7,788 (240)

From nanoscopic to macroscopic photo-driven motion in azobenzene-containing materials

Nanophotonics, 2018
The illumination of azobenzene molecules with UV/visible light efficiently converts the molecules between trans and cis isomerization states. Isomerization is accompanied by a large photo-induced molecular motion, which is able to significantly affect ...
Oscurato Stefano L., Salvatore Marcella, Maddalena Pasqualino, Ambrosio Antonio   +3 more
doaj   +1 more source

Strategies to control humidity sensitivity of azobenzene isomerisation kinetics in polymer thin films

Communications Materials
Azobenzenes are versatile photoswitches that garner interest in applications ranging from photobiology to energy storage. Despite their great potential, transforming azobenzene-based discoveries and proof-of-concept demonstrations from the lab to the ...
Sami Vesamäki, Henning Meteling, Roshan Nasare, Antti Siiskonen, Jani Patrakka, Nelmary Roas-Escalona, Markus Linder, Matti Virkki, Arri Priimagi   +8 more
doaj   +1 more source

In Silico to In Cerebro—Development of the Orexin Receptor Antagonist “Photorexant” for Photomodulation In Vitro and in Mouse Brains

Angewandte Chemie International Edition, EarlyView.
Following a structure‐based design approach, photoswitchable derivatives of the FDA‐approved drug suvorexant were designed, docked, synthesized, and characterized pharmacologically at the orexin 1 and 2 receptors (OX1R and OX2R). Optimized “photorexant” showed up to an 11‐fold difference in IC50 between photoisomers, enabled dynamic and reversible ...
Marcus Angermann, Marie H. Deventer, Vicente Ledesma‐Martin, Nuno Martinho, Alix Flake, Silvia Mori, Angel Nuñez, Jaime Pignatelli, Rita C. Guedes, Christophe P. Stove, Michael Decker   +10 more
wiley   +1 more source

Affinity Peptides With pH Sensitivity for the Enrichment of CD38+ Cells

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The selective enrichment of cell populations based on surface markers is critical for the advancement of gene and cell therapies. Current antibody‐based cell isolation methods, such as fluorescence‐ and magnetic‐activated cell sorting (FACS and MACS), offer high specificity but are limited by scalability, cost, and potential adverse effects on
Gabrielle Rusch, Mickael Meyer, I. Mohamed Irfan, Carson Huber, Joseph Burclaff, Scott T. Magness, Stefano Menegatti, Michael Daniele   +7 more
wiley   +1 more source

Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers

Chemistry – A European Journal, EarlyView.
ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda, Alan Pham, SreeNidhi Karnati, Natalia Soto Rodriguez, Alyssa Toner, Wenshe Ray Liu   +5 more
wiley   +1 more source

Dynamic Control of Nucleic Acids Self‐Assembly and Expression Using Photoswitches

Chemistry – A European Journal, EarlyView.
We review here the recent progress made in the design of molecular photoswitches, and highlight their implementation for the dynamic control over nucleic acids self‐assembly and expression. ABSTRACT Synthetic nucleic acids have become readily available and now constitute versatile building blocks in materials science—where they can be used to engineer ...
Noemí Nogal, Hugo Laigle, Maxime Mansy, Sébastien Ulrich, Mathieu Surin   +4 more
wiley   +1 more source

Solvent Effects on the Conformational Preferences of 2,6‐Pyridylcarboxamide Foldamers

Chemistry – A European Journal, EarlyView.
The marked effect of organic solvents and water/methanol mixtures on the conformational preferences of a soluble chiral foldamer has been established in a diverse array of seventeen distinct environments. ABSTRACT The marked influence of organic solvents and water on the conformational preferences of a chiral, soluble 2,6‐pyridylcarboxamide foldamer ...
Alexander R. Davis, Sena Öztürk, Kushal Samanta, Louise Male, Adam A. L. Michalchuk, Sarah J. Pike   +5 more
wiley   +1 more source

Azobenzene as an Effective Ligand in Europium Chemistry—A Synthetic and Theoretical Study

Molecules
The preparation and characterization of two novel europium–azobenzene complexes that demonstrate the effectiveness of this ligand for stabilizing reactive, redox-active metals are reported.
Damian G. Allis, Ana Torvisco, Cody C. Webb, Miriam M. Gillett-Kunnath, Karin Ruhlandt-Senge   +4 more
doaj   +1 more source

Fully Reversible Regulation of 8‐17 DNAzyme Activity Using Nucleoside‐Based Diarylethenes

Chemistry – A European Journal, EarlyView.
The site‐specific incorporation of nucleosidic diarylethenes into the 8–17 deoxyribozyme (DNAzyme) identified position 2.1 as optimal. Compound dU‐PhtBu enabled efficient light‐dependent control of catalytic activity, while maintaining thermal stability and reversibility.
Jörn Bargstedt, Simon M. Büllmann, Sophia Conwell, Andres Jäschke   +3 more
wiley   +1 more source

Metal‐Ion Regulated Light‐Free Z→E Isomerization of Azobenzene Glycomacrocycle

Chemistry – A European Journal, EarlyView.
Metal ion‐catalyzed Z→E isomerization of photoswitchable azobenzene glycomacrocycle: A new azobenzene‐based glycomacrocycle is capable of forming a 1:1 complex with divalent metal ions in both E‐ and Z‐isomers. The complexes undergo light‐free Z→E isomerization in a timescale spanning from seconds to weeks.
Yang Zhou, Jinbiao Jiao, Mathieu Lordez, Jean‐Yves Salpin, Juan Xie   +4 more
wiley   +1 more source