Results 11 to 20 of about 428 (148)

Reagentless photochemical transformations of dihydrofuropyridinones to azocines

, 2021
Herein, the thermal and photochemical reactions of dihydrofuropyridinones will be described. Thermal rearrangements of alkynylcyclobutenones are well established routes to benzoquinones, cyclopentediones and furanones; all of which are found in several natural products.
Manning, Morgan Ann
core   +3 more sources

Highlighting the Rich Chemistry of the Allenone Moiety

Advanced Synthesis &Catalysis, Volume 365, Issue 9, Page 1332-1384, May 12, 2023., 2023
Abstract Conjugated and non‐conjugated allenones appear as recurring motifs in organic synthesis, natural products and mechanistic investigations showing unique properties and applications. The ability of allenones to build cycles has provided a direct access to strained systems, medium‐sized rings, arenes, heterocycles and complex polycycles.
José M. Alonso, Pedro Almendros
wiley   +1 more source

The Oxford Catalogue of Opioids: A systematic synthesis of opioid drug names and their pharmacology

British Journal of Clinical Pharmacology, Volume 87, Issue 10, Page 3790-3812, October 2021., 2021
Aim The growing demand for analgesia, coupled with an increasing need to treat opioid dependence and overdose, has escalated the development of novel opioids. We aimed to quantify the number of opioid drugs developed and to catalogue them based on their pharmacology.
Georgia C. Richards, Konrad Sitkowski, Carl Heneghan, Jeffrey K. Aronson   +3 more
wiley   +1 more source

Nature‐Inspired Functional Chromophores from Biomimetic o‐Quinone Chemistry

European Journal of Organic Chemistry, Volume 2021, Issue 21, Page 2982-2989, June 7, 2021., 2021
Bioinspired manipulation of o‐quinones generated from natural catechols represents a straightforward strategy to access the diverse molecular scaffolds endowed with peculiar functional chromophores, which offers a finely tunable palette of colors, emissions and input/output opportunities in response to pH, light, oxidant species and other external ...
Maria Laura Alfieri, Lucia Panzella, Orlando Crescenzi, Alessandra Napolitano, Marco d'Ischia   +4 more
wiley   +1 more source

Synthesis of 4-amino-substituted tetrahydropyrimido[4,5-d]azocines

, 2020
A method for the preparation of 4-amino-substituted tetrahydropyrimido[4,5- d]azocines containing an aromatic pyrimidine fragment has been developed.
Sorokina E.A., Ovcharov M.V., Kulikova L.N., Borisova T.N., Varlamov A.V., Voskressensky L.G., Listratova A.V., Gromov S.P.   +7 more
core   +2 more sources

The reaction of tetrahydrochromeno[3,4-c]pyridines with activated alkynes. the first synthesis of tetrahydrochromeno[4,3-d]azocines

, 2020
The first synthesis of tetrahydrochromeno[4,3-d]azocines via an alkyne-induced expansion reaction is described. © 2011 Elsevier Ltd.
Khrustalev V.N., Ovcharov M.V., Gozun S.V., Kulikova L.N., Borisova T.N., Varlamov A.V., Voskressensky L.G., Listratova A.V.   +7 more
core   +2 more sources

An Isosteric Triaza Analogue of a Polycyclic Aromatic Hydrocarbon Monkey Saddle

Chemistry – A European Journal, Volume 26, Issue 64, Page 14560-14564, November 17, 2020., 2020
Monkey business: Isosteric exchange of CH↔N in a chiral monkey saddle makes the difference, N is increasing the conformational stability and significantly reduces the frequency of the bowl‐to‐bowl‐inversion. Abstract Since a few years, the interest in negatively‐curved fused polycyclic aromatic hydrocarbons (PAHs) has significantly increased. Recently,
Tobias Kirschbaum, Frank Rominger, Michael Mastalerz   +2 more
wiley   +1 more source

First efficient one-pot synthesis of tetrahydropyrrolo[2,3-d]azocines and tetrahydroazocino[4,5-b]indoles

, 2020
A new efficient one-pot protocol for the synthesis of tetrahydropyrrolo[2,3-d]azocines and tetrahydroazocino[4,5-b]indoles starting from ready-available tetrahydropyrrolo[3,2-c]pyridines and tetrahydropyrido[4,3-b]indoles correspondingly and ...
Soklakova T.A., Kulikova L.N., Borisov R.S., Borisova T.N., Varlamov A.V., Voskressensky L.G.   +5 more
core   +2 more sources

Reactions of tetrahydropyrido[4,5-d][1,2,4]triazolo[1,5-a]-pyrimidin-4-ones with activated alkynes. Synthesis of [1,2,4]triazolo[1′,5′:1,2] pyrimido[4,5-d]azocines

, 2020
Triazolo[1′,5′:1,2]pyrimido[4,5-d]azocines were synthesized by the tandem expansion of the tetrahydropyridine ring in tetrahydropyridotriazolopyrimidines by the action of activated alkynes.
Sorokina E.A., Khrustalev V.N., Ovcharov M.V., Borisova T.N., Varlamov A.V., Voskressensky L.G.   +5 more
core   +2 more sources

Non‐Alternant Nanographenes Bearing N‐Doped Non‐Hexagonal Pairs: Synthesis, Structural Analysis and Photophysical Properties

Angewandte Chemie, Volume 136, Issue 42, October 14, 2024.
Progress in the development of non‐alternant nanographenes containing N‐doped non‐hexagonal pairs, including N‐doped pentagon‐heptagon (5–7) pairs, N‐doped pentagon‐octagon (5–8) pairs and N‐doped heptagon‐heptagon (7–7) pairs, is comprehensively covered in this review.
Huan Luo, Junzhi Liu
wiley   +2 more sources