Results 171 to 180 of about 40,795 (299)

Molecular mechanisms of azole resistance in fungi [PDF]

, 1997
T Joseph-Horne
openalex   +1 more source

Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi

Advanced Science, Volume 12, Issue 37, October 6, 2025.
The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda, Kaila Petronila Medina‐Alarcón, João Paulo Soler Gonçalves Pereira, Thais Cristina dos Anjos Sevilhano, Brigitte Aguilar‐Morón, Fernando Díaz‐Cárdenas, Lucas Silva da Cruz, Francisco Humberto Xavier‐Júnior, Eduardo Festozo Vicente, João Perdigão, Beatriz G. de la Torre, Fernando Albericio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Real‐world population pharmacokinetics of tezacaftor‐ivacaftor in children with cystic fibrosis: The SYM‐CF study

British Journal of Clinical Pharmacology, Volume 91, Issue 10, Page 2969-2978, October 2025.
Aims The clinical effectiveness of tezacaftor‐ivacaftor in children with cystic fibrosis (cwCF) varies; some patients respond while others do not or have adverse effects. The pharmacokinetics (PK) of tezacaftor‐ivacaftor are inadequately published, especially in children.
Steffie E. M. Vonk, Suzanne W. J. Terheggen‐Lagro, Eric G. Haarman, Hettie M. Janssens, Anke‐Hilse Maitland–van der Zee, E. Marleen Kemper, Ron A. A. Mathôt, on behalf of the Amsterdam Mucociliary Clearance Disease (AMCD) research group   +7 more
wiley   +1 more source

Cross-resistance to polyene and azole drugs in Cryptococcus neoformans [PDF]

, 1995
Tim Joseph‐Horne, D. W. Hollomon, R. S. Thomas Loeffler, Steven L. Kelly   +3 more
openalex   +1 more source

The azole antifungal drugs [PDF]

Journal of Antimicrobial Chemotherapy, 1987
openaire   +3 more sources

A Rare Case of Blastomycosis in a Psoriasis Patient Treated With Ustekinumab (Stelara)

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Psoriasis is a chronic inflammatory skin condition mediated by T‐helper 1 (Th1) and T‐helper 17 (Th17) cytokines, including interleukin (IL)‐12, IL‐23, IL‐17, and tumor necrosis factor alpha (TNF‐α). Ustekinumab, a human monoclonal antibody against the p40 subunit of IL‐12/23, has revolutionized treatment of moderate to severe psoriasis but ...
Fatima Ghaffar, Ahmed Hassan, Masab Ali, Hafiz Noman Ijaz, Sajjad Jameel, Monika Kumari, Muhammad Husnain Ahmad   +6 more
wiley   +1 more source

Palladium-catalyzed reactions of terminal acetylenes and olefins with halo-1,3-azoles.

, 1987
Takao Sakamoto, Hideo Nagata, Yoshinori Kondo, Masafumi Shiraiwa, Hiroshi Yamanaka   +4 more
openalex   +2 more sources

Oxidant‐Free Amidation of Aldehydes Enabled by Electrophotocatalysis

Chemistry – A European Journal, Volume 31, Issue 55, October 1, 2025.
An electrophotocatalytic method for C(sp2)–N bond formation via radical‐polar crossover (RPC)‐HAT catalysis is presented. The mild operating conditions enable functionalization of a wide range of compounds, with electricity as the sole oxidant. Abstract Electrophotocatalysis (EPC) is emerging as a powerful tool in organic synthesis, offering unique ...
Dimitris I. Ioannou, Elena Bombonato, Jiri Sanramat, Joost N. H. Reek, Timothy Noël   +4 more
wiley   +1 more source

Pre-emptive therapy with azoles in lung transplant patients [PDF]

, 1999
Jürg Hamacher, Anastase Spiliopoulos, A-M Kurt, Laurent Nicod, and the Geneva Lung Transplantation Group   +4 more
openalex   +1 more source

The serine palmitoyl transferase of plant pathogenic fungi: a promising new target for the development of novel crop protection solutions†

Pest Management Science, Volume 81, Issue 10, Page 6567-6578, October 2025.
High biological activity of pyridazine carboxamides against a wide range of Ascomycetes led to identification of a new biochemical target for agrochemical fungicides – serine palmitoyl transferase. Abstract BACKGROUND Plant pathogens pose a significant threat to global agriculture and, thus to world food supplies, requiring the development of ...
Lionel Nicolas, Emilia Hilz, Stephanie Gamet, Vincent Thomas, Stephane Peyrard, Luigi Di Vietro, Benedicte Cirer, Julie Geist, Bernd Essigmann, Anne Ferry, Angeline Chanel, Frédéric Berniaud, Dominik Schwarz, Virginie Lempereur   +13 more
wiley   +1 more source