Results 41 to 50 of about 868 (168)

Kinetic Resolution of Alkylidene Norcamphors via a Ligand-Controlled Umpolung-Type 1,3-Dipolar Cycloaddition

iScience, 2019
Summary: Development of a general catalytic and highly efficient method utilizing readily available precursors for the regio- and stereoselective construction of bioactive natural-product-inspired spiro architectures remains a formidable challenge in ...
Chong Shen, Yuhong Yang, Liang Wei, Wu-Wei Dong, Lung Wa Chung, Chun-Jiang Wang   +5 more
doaj   +1 more source

azomethine ylides

, 2008
Citation: 'azomethine ylides' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.A00565 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Alkoxyallenes in Modern Synthesis: Reactivity, Catalysis, and Complexity Generation

Advanced Synthesis &Catalysis, Volume 368, Issue 17, 1 September 2026.
The last decade has witnessed a remarkable transformation in alkoxyallene chemistry. Although historically employed as synthetic equivalents of acrolein or as versatile 3C synthons, alkoxyallenes are now increasingly recognized as highly adaptable platforms for synthetic design.
A. Lanfranco, M. Rusconi, J. Saglietto, P. Renzi, A. Deagostino, E. Azzi   +5 more
wiley   +1 more source

1,3-Dipolar Cycloaddition in the Preparation of New Fused Heterocyclic Compounds via Thermal Initiation

Molecules, 2016
This paper describes the synthesis of precursors with a benzo[b]furan skeleton for the intramolecular 1,3-dipolar cycloaddition of azomethine ylides prepared from N-substituted 3-allyl-aminobenzo[b]furan-2-aldehydes and secondary amines derived from α ...
Martin Porubský, Lukáš Tenora, Milan Potáček   +2 more
doaj   +1 more source

Stereoselective Synthesis of the Di-Spirooxindole Analogs Based Oxindole and Cyclohexanone Moieties as Potential Anticancer Agents

Molecules, 2021
A new series of di-spirooxindole analogs, engrafted with oxindole and cyclohexanone moieties, were synthesized. Initially, azomethine ylides were generated via reaction of the substituted isatins 3a–f (isatin, 3a, 6-chloroisatin, 3b, 5-fluoroisatin, 3c ...
Abdullah Mohammed Al-Majid, M. Ali, Mohammad Shahidul Islam, Saeed Alshahrani, Abdullah Saleh Alamary, Sammer Yousuf, M. Iqbal Choudhary, Assem Barakat   +7 more
doaj   +1 more source

Retro‐Hetero‐Michael Addition Strategies in Organic Synthesis

European Journal of Organic Chemistry, Volume 29, Issue 32, 24 August 2026.
In this review, synthetic approaches to carbo‐ and heterocyclic compounds, including natural products, published in the last 15 years (2011–2025) which have either relied upon or included a retro‐hetero‐Michael addition step at any stage are discussed.
Dina Scarpi, Ernesto G. Occhiato
wiley   +1 more source

Multicomponent synthesis of spiropyrrolidine analogues derived from vinylindole/indazole by a 1,3-dipolar cycloaddition reaction

Beilstein Journal of Organic Chemistry, 2016
A new series of spiropyrrolidine compounds containing indole/indazole moieties as side chains have been accomplished via a one-pot multicomponent synthesis.
Manjunatha Narayanarao, Lokesh Koodlur, Vijayakumar G. Revanasiddappa, Subramanya Gopal, Susmita Kamila   +4 more
doaj   +1 more source

Design, Synthesis, X‐Ray Crystallographic Characterization, Anticholinesterase and Antioxidant Evaluation, and Molecular Modeling of Novel Dispiroindene‐Pyrrolidine Derivatives as Multifunctional Anti‐Alzheimer Agents

Drug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT A novel series of 5‐chloro‐N‐alkyl‐1′,1″‐dimethyl‐4′‐aryldispiro[indene‐2,3′‐pyrrolidine‐2′,3″‐indoline]−1,2″(3H)‐diones (4a–r) was rationally designed and synthesized via a one‐pot multicomponent reaction of N‐alkylated 5‐chloroisatin derivatives, 2‐(arylmethylidene)−2,3‐dihydro‐1H‐inden‐1‐ones (2a–i), and sarcosine (3).
Aisha A. Alsfouk, Riham A. El‐Shiekh, Benson M. Kariuki, Eman Sabry, Mohamed G. Abouelenein, Asmaa Saleh, Mahmoud G. A. Saleh, Aladdin M. Srour   +7 more
wiley   +1 more source

Funktionalisierung von Peptiden auf der festen Phase im späten Synthesestadium

Angewandte Chemie, Volume 138, Issue 31, 27 July 2026.
Peptidmodifikationen sind für die Kontrolle der Eigenschaften von Peptidwirkstoffen von entscheidender Bedeutung. Daher sind Strategien, die einen effizienten und schnellen Einbau nicht‐kanonischer Modifikationen in Peptide in Parallelformaten ermöglichen, sehr gefragt.
Marius Werner, Truc Lam Pham, Franziska Thomas   +2 more
wiley   +1 more source

Copper–phenanthroline catalysts for regioselective synthesis of pyrrolo[3′,4′:3,4]pyrrolo[1,2-a]furoquinolines/phenanthrolines and of pyrrolo[1,2-a]phenanthrolines under mild conditions

Beilstein Journal of Organic Chemistry, 2014
A new series of pyrrolo[3′,4′:3,4]pyrrolo[1,2-a]furoquinolines/phenanthrolines and pyrrolo[1,2-a]phenanthrolines were efficiently built up from an 8-hydroxyquinoline derivative or phenanthroline via 1,3-dipolar cycloaddition reaction involving non ...
Rupankar Paira, Tarique Anwar, Maitreyee Banerjee, Yogesh P. Bharitkar, Shyamal Mondal, Sandip Kundu, Abhijit Hazra, Prakas R. Maulik, Nirup B. Mondal   +8 more
doaj   +1 more source