Results 111 to 120 of about 35,229 (220)
Genetic defects in human azoospermia
Basic and Clinical Andrology, 2019 As with many other diseases, genetic testing in human azoospermia was initially restricted to karyotype analyses (leading to diagnostic chromosome rearrangement tests for Klinefelter and other syndromes). With the advent of molecular biology in the 1980s,
F. Ghieh +3 more
semanticscholar +1 more source
Andrology, EarlyView.ABSTRACT Background Klinefelter syndrome (KS), typically characterized by a 47, XXY karyotype, is the most common sex chromosomal aneuploidy in males, with a prevalence of approximately one in 600–660 individuals. Despite its frequency, the syndrome remains significantly underdiagnosed, with 50%–75% of affected individuals never receiving a clinical ...
Francesca Allosso +2 more
wiley +1 more source
Systematic analysis of protein interaction network associated with azoospermia [PDF]
, 2016 Non-obstructive azoospermia is a severe infertility factor. Currently, the etiology of this condition remains elusive with several possible molecular pathway disruptions identified in the post-meiotic spermatozoa.
Soudabeh Sabetian +3 more
core +1 more source
Bi-allelic Recessive Loss-of-Function Variants in FANCM Cause Non-obstructive Azoospermia.
American Journal of Human Genetics, 2018 Infertility affects around 7% of men worldwide. Idiopathic non-obstructive azoospermia (NOA) is defined as the absence of spermatozoa in the ejaculate due to failed spermatogenesis.
L. Kasak +12 more
semanticscholar +1 more source
European Journal of Haematology, EarlyView.ABSTRACT Concerns about treatment‐related fertility impairment are common among young adult lymphoma survivors. Evidence on the impact of treatment for aggressive non‐Hodgkin lymphoma (NHL) on future childbearing is limited, although many individuals of reproductive age are affected.
Stefanie Antonilli +10 more
wiley +1 more source
Diagnosis and treatment of obstructive azoospermia
, 2004 There are two types of azoospermia, namely, obstructive and nonobstructive azoospermia. Urologists play a more important role in the former, because many patients of the former can expect spontaneous pregnancy after surgical reconstruction of the seminal
六車, 光英 +2 more
core
Reversibility of azoospermia induced by bacillus Calmette-Guerin
, 1986 A single intratesticular injection of bacillus Calmette-Guerin induces azoospermia within 3 to 6 weeks in a variety of animals without loss of androgens. After a period of azoospermia, the return of spermatogenesis was observed in dogs and monkeys. Seven
Talwar, G. P., Naz, R. K.
core +1 more source
The FEBS Journal, EarlyView.FTO regulates mRNA stability and translational efficiency through its m6A‐demethylation activity. GSK3 functions as an upstream regulator of FTO, leading to its inhibition via phosphorylation. In male germ cells, FTO activity is kept in check by GSK3α.
Neha Choudhari +7 more
wiley +1 more source
Clinicogenetic Characterization of H Syndrome in a South African Child
Pediatric Dermatology, EarlyView.ABSTRACT H syndrome is a rare autosomal recessive genodermatosis caused by loss‐of‐function SLC29A3 variants, combining hyperpigmented indurated plaques and hypertrichosis with life‐threatening autoinflammation. We report a 5‐year‐old South African girl of first‐cousin parents who presented with hyperinflammation mimicking macrophage activation ...
Tshimogo Tswelopele Sathekge +1 more
wiley +1 more source
Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.Long‐term repeated immunisation against GnRH resulted in the absence of active spermatogenesis and may lead to irreversible infertility in dwarf bucks and baboons. Histological examination revealed a marked reduction of the seminiferous tubular lumen, complete depletion of germ cells, germ cell vacuolization and tubular hyalinization.
Teresa Ferrín +8 more
wiley +1 more source