Results 51 to 60 of about 2,475 (111)

Loss of ADAP1/CentA1 Protects Against Autoimmune Demyelination

open access: yesThe FASEB Journal, Volume 39, Issue 9, 15 May 2025.
ADAP1/CentA1 is an actin‐binding protein highly expressed in neurons. Our study describes a novel immunomodulatory function for ADAP1/CentA1 in the context of autoimmune demyelination. Mice lacking ADAP1/CentA1 were found partially resistant to the multiple sclerosis (MS) model experimental autoimmune encephalomyelitis (EAE) due to an altered ...
Jonathan J. Carver   +6 more
wiley   +1 more source

Plasminogen Activator Inhibitor 1 Controls Abdominal Aortic Aneurism Formation via the Modulation of TGF‐β/Smad2/3 Signaling in Mice

open access: yesThe FASEB Journal, Volume 39, Issue 9, 15 May 2025.
Graphical illustration of the mechanism underlying the acceleration of plasminogen activator inhibitor1 deletion‐mediated abdominal aneurysm formation in mice undergoing calcium chloride2 induction surgery. Genetic intervention targeted toward plasminogen activator inhibitor1 accelerated AAA formation via the modulation of TGF‐β/Smad2/3 signaling in ...
Mantong Zhao   +10 more
wiley   +1 more source

Human immunodeficiency virus infection of the human thymus and disruption of the thymic microenvironment in the SCID-hu mouse. [PDF]

open access: yes, 1993
Infection with the human immunodeficiency virus (HIV) results in immunosuppression and depletion of circulating CD4+ T cells. Since the thymus is the primary organ in which T cells mature it is of interest to examine the effects of HIV infection in this ...
Adelsberger, J   +9 more
core  

Studies in malaria chemotherapy [PDF]

open access: yes, 1946
This thesis is an account of the study of some aspects of experimental malaria therapy carried out in an Army Research Team during the period July 1944 to January 1946.
Innes, James
core  

The structure and function of sponge cells: New criteria for the taxonomy of poecilosclerid sponges (Demospongiae) [PDF]

open access: yes, 1968
The skeletal morphology, histology, cytology, and cytochemistry of fifteen species of marine poecilosclerid sponges have been investigated….https://elischolar.library.yale.edu/peabody_museum_natural_history_bulletin/1024/thumbnail ...
Simpson, Tracy L.
core   +1 more source

METHYLENE BLUE-AZURE B-EOSIN STAINING METHOD FOR THIN METHACRYLATE SECTIONS OF BONE MARROW

open access: yesACTA HISTOCHEMICA ET CYTOCHEMICA, 1978
Bone marrow specimens were removed from the femurs of gerbils perfused with 10% buffered formalin. They were embedded in methacrylate and sectioned on a Sorvall JB-4 microtome at 1 to 3μm at 0.5μm intervals. Staining was accomplished with methylene blue-azure B-eosin as follows: Slides were immersed in the methylene blue-azure B mixture for 1min ...
openaire   +3 more sources

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