Results 101 to 110 of about 923 (130)

Comparative Analysis of Viral Load Quantification Using Reverse Transcription Polymerase Chain Reaction and Digital Droplet Polymerase Chain Reaction. [PDF]

open access: yesInt J Mol Sci
Gebe Abreu Cabral P   +9 more
europepmc   +1 more source

Azvudine versus Paxlovid in COVID‐19: A systematic review and meta‐analysis

Reviews in Medical Virology
This systematic review and meta‐analysis aimed to compare the effectiveness and safety of azvudine versus nirmatrelvir/ritonavir (Paxlovid) in treating coronavirus disease 2019 (COVID‐19).
Behnam Amani, Bahman Amani
semanticscholar   +3 more sources

Azvudine Suppresses Epithelial–Mesenchymal Transition in Hepatocellular Carcinoma by Targeting the Notch–HEY Signalling Pathway

open access: yesInternational Journal of Molecular Sciences
Azvudine (FNC) is a novel cytidine analogue that is widely used in the treatment of infectious diseases such as AIDS and COVID-19. Previous studies have demonstrated its anticancer activity in various cancer cell lines, including non-Hodgkin’s lymphomas ...
Yao Meng   +10 more
semanticscholar   +2 more sources

Adsorption Potential of Ag Nanoparticles with Azvudine (FNC) Investigated by Density Functional Theory and Raman Spectroscopy.

Langmuir
Azvudine (FNC) is a dual-target inhibitor of HIV reverse transcriptase and accessory protein Vif, which can effectively inhibit the reverse transcription and replication of the HIV virus in vivo and can also be used for the treatment of novel coronavirus
Qi Wang   +5 more
semanticscholar   +3 more sources

Azvudine and mortality in patients with coronavirus disease 2019: A retrospective cohort study

International Immunopharmacology, 2023
Several studies have found that azvudine (FNC) can inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication both in vivo and in vitro. However, the effect of FNC on the risk of death in patients with coronavirus disease 2019 (COVID-19) is unclear.
Bin Liu   +7 more
openaire   +2 more sources

A Nearly 20‐Year Journey to Success of Azvudine for Antiviral Therapy

Chinese Journal of Chemistry, 2023
Comprehensive SummaryModified nucleosides, particularly those with 4'‐modifications, are significant nucleosides used in antiviral treatments. The drug discovery campaign of Azvudine starts from 2′‐deoxynucleoside, followed by extensive modifications, such as introducing the 4’‐position substitutions, a 2’‐β‐fluoro atom, and changing the nucleobases ...
Bin Yu, Junbiao Chang
openaire   +1 more source

Real‐world effectiveness of Azvudine versus nirmatrelvir–ritonavir in hospitalized patients with COVID‐19: A retrospective cohort study

Journal of Medical Virology, 2023
Chinese guidelines prioritize the use of Azvudine and nirmatrelvir–ritonavir in COVID‐19 patients. Nevertheless, the real‐world effectiveness of Azvudine versus nirmatrelvir–ritonavir is still lacking, despite clinical trials showing their effectiveness ...
Guangtong Deng   +11 more
semanticscholar   +1 more source

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